Ruslan Dmitriev
@PhotoBioLab
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Associate Professor @ResearchUGent @UGent_HSR @microscopyUGent 'FLIM gypsy' and developer of #FLIM #PLIM bio-/nanosensors for #organoids #3D PI @FlImagin3_DN
Ghent University, Belgium
Joined January 2010
#PublicationAlert #FluorescenceTuesday Our paper (see the tweet below) has been published in @LightSciAppl ! Enjoy!
@photobiolab #PreprintAlert! We are excited to share our new preprint reporting how can #FLIM #organoids can help better understanding #MNP #nanoplastic #pollution effects! We developed #FLIMbarcoding with #NIR #azabodipy #pristinenanoparticles, optimised #polarityreversion 👇
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Happy to share the news that our collaboration with @bert_devriendt has resulted in a paper on #mRNAvaccine #LNP development, where we used #FLIM and #organoids with controlled polarity to trace & validate mRNA successful delivery! Long live #FLIM! @microscopyUGent @FlImagin3_DN
Super excited to share our latest publication in @JCRnEDITORS! We report on cell-specific mRNA delivery via nanobody-functionalized LNPs with applications in mRNA delivery to gut tissues. Big shout to Linglong Chen! https://t.co/2lyDGh8NZr
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Check out our new resource paper @CellStemCell, where we present a brain organoid atlas of human neurodevelopmental disorders. Surprising was that nearly all patients had abnormal organoids. The challenge was aligning defects to clinical. https://t.co/0YtGTd4Dwb
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Nature research paper: Spatial metabolic gradients in the liver and small intestine https://t.co/QwgPMepyTt
nature.com
Nature - Mapping of spatial metabolic gradients in the mouse liver and intestine identifies fructose-induced focal derangements in liver metabolism.
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The Lipid Brain Atlas is out now! If you think lipids are boring and membranes are all the same, prepare to be surprised. Led by Luca Fusar Bassini with Gioele La Manno's lab, we mapped membrane lipids in the mouse brain at high resolution. https://t.co/q3AeqGsIS1
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This #FluorescenceFriday we showcase live 3D #autofluorescence image of iPSC-derived human neural organoids, 21 'days old': multiple #neuralrosette presence &3D structures are evident in cyan (NADH) and pseudocolor #FLIM images. Taken together with @Norevanloon @microscopyUGent
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A #phasorplot is a graphical representation of #FLIM that makes FLIM data easier to interpret, compare, and communicate. Learn more on #FLIMphasors joining our free Webinar hosted by Alex Vallmitjana from #GSLab on October 15th at 4 PM CET – 7AM PST 👉 https://t.co/B9bGuyXaZU
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Connect with your global community at #bps2026! Only 3 days left until the abstract deadline on October 1 https://t.co/rOLkTWopk6
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#FluorescenceFriday today we have a snapshot of cell proliferation (S phase labelling by Hoechst, BrdU& #phasorFLIM) imaging in live mouse intestinal organoids. Different colour nuclei indicate different cell cycle stage with #NADH & lumen AF! #workinprogress @hang_zhouFLIM
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Press release @EurekAlert: a bit shorter read about our recent study on #FLIM #organoids #nanoplastics
eurekalert.org
Increased micro- and nanoplastic (MNP) pollution and its poorly understood biomedical impacts raise questions on their cell and tissue uptake mechanisms and effects on the absorptive tissues....
#PublicationAlert #FluorescenceTuesday Our paper (see the tweet below) has been published in @LightSciAppl ! Enjoy!
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Main highlights of our new study: #nanoplastics #FLIM #epithelialpolarity reversion and live microscopy of #gut_organoids #phasorFLIM quantification & 'barcoding' and very cool #mitochondria mobility and polarization @GgigGhent @FlImagin3_DN @organoidscience @napari_imaging
#LSA_Highlight: [Article] Visualizing the internalization and biological impact of nanoplastics in live intestinal organoids by Fluorescence Lifetime Imaging Microscopy (FLIM). @ugent @tugraz #Biophotonics #Imaging_and_sensing #Nanoparticles
https://t.co/sKxUTA8cgW
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Excited to share our latest preprint led by Kelli Johnson- Mapping mesenchymal diversity in the developing human intestine and organoids! We defined 5 mesenchymal populations occupying discrete anatomical locations within the human intestine. https://t.co/rzSfsdGhjO
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Congrats with another milestone @JalinkLab! Looking forward to read it @FlImagin3_DN
Super happy that we have finally put this work out!!! 4 years in the making: We present – DynaScreen: an imaging (FRET-FLIM) based pooled CRISPR screening platform for studying “dynamic” phenotypes. short🧵below (1/n)
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Cancer cells turbocharge themselves by stealing the energy-producing units from neurons in tumours https://t.co/j0nOSbwCzJ
nature.com
Nature - The theft probably helps the cells to spread around the body, and preventing it could provide a path to treatment, researchers say.
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#FluorescenceFriday an image from our project on #FLIM-based assessment of #nanoplastic pollution with polarity-reverted small #intestinal #organoids. Immunofluorescence of ZO-1 (cyan) together with F-actin (green) and NPs (magenta). With @hang_zhouFLIM @FlImagin3_DN Stay safe!
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#FluorescenceFriday the 3rd @FlImagin3_DN consortium in Milan! ~Halfway of PhD so many exciting directions in #FLIM #cancermechanics #diatoms #organoids #SPIM #FRET #heartrepair and more with @drmgmonaghan @Femtoscopist @MicroSensing @hang_zhouFLIM @melissa_skala @chiarellast ..
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Woah! Such an important study published in Nature today! Quick thread with some of their key figures! 🧵
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