Orchard Lab
@OrchardLab_Rob
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The Orchard lab at UTSW! Host-pathogen interactions using functional genomics, mouse models, and whatever it takes.
Joined June 2018
Incredibly proud of my former @UTSWGradSchool student Christina Zarek and her paper in @PLOSPathogens!!! There is still so much to learn about the biology of #coinfection with #herpesvirus and #parasites!
Helminth infections exacerbate chronic herpesvirus infection. Importantly, the mechanism by which this occurs is dependent on the order of coinfection. Learn more in this recent study 🔎 https://t.co/g0itrcii8Y
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A postdoc position in my lab @utswimmuno is still available. This is for a joint project with Dr. Shin Yamazaki @UTSWNeurosci. We are in the UT Southwestern Circadian Clock research community led by Dr. Joseph Takahashi (@CircadianClocks). #GutClock.
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I am honored to join the Pew community @pewtrusts @pewhealth as a 2023 Biomedical Scholar! Thank you to my team and mentors @LHooperLab, @CircadianClocks, @BillDauerNeuro, and Vassilis Pachnis @TheCrick
https://t.co/e3pepxHt6e
@UTSWNews @UTSWBrain
pew.org
Pew has a decades-long commitment to support groundbreaking research by promising early-career biomedical scientists in the United States and Latin America. Our multiyear grants encourage informed...
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Happening today at noon!!
If you haven't seen the email, we will be co-hosting Dr. Johnathon Abrahams with the #Immunology department THIS WEDS, May 3rd! Information about his talk is attached. Please attend the talk if you can!
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Congratulations to Drs. Russell DeBose-Boyd and Duojia Pan on their selection to the @theNASciences @UTSWGradSchool @UTSWNews
nasonline.org
Featured News View All News News from the National Academies News and features from the National Academies of Sciences, Engineering, and Medicine (NASEM). Learn More
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Check out this cool paper from @TiffanyReeseLab and @HancksLab ! Fun to see the story develop over time and glad to play a small part in it!
#viruses are the best cell biologists! We discover a new viral mimic of a host cell death protein required for #norovirus egress! @wang_guoxun @HancksLab @OrchardLab_Rob @utswimmuno @utswnews 🧵 1/ https://t.co/Lh6j1d2Oqc
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Beth Levine, MD was an internationally renowned pioneer in autophagy. To continue her legacy; UT Southwestern has introduced the Beth Levine, M.D Prize in Autophagy to be awarded to exceptional researchers and scientists who have made significant contributions to the field of
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Congratulations to Emily on her manuscript describing a new antiviral pathway and its antagonism by poxvirus A51R proteins! Check out the preprint on biorxiv: https://t.co/mlVfeNfj5m
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How is norovirus infection in tuft cells controlled? A collaboration work with @WilenLab shows short-lived tuft cells are the reservoir. Tuft-cell-intrinsic + extrinsic IFN-I & -III control norovirus in the gut. Now published in @CellReports
Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity: Cell Reports
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Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity: Cell Reports
cell.com
Strine et al. interrogate the determinants and consequences of tuft cell tropism on murine norovirus infection. Using enteroid and mouse models, they show that tuft cells are required for persistent...
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Please RT. We are recruiting at the PI level. The department is in the process of being renamed Lab of Neurological Infections & Immunity. All CNS pathologic insult (virus, prion, bacteria) of interest!
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Congratulations to our Immunology Department Chair @LHooperLab for election to National Academy of Medicine! @theNAMedicine @UTSWNews @utswimmuno 🎉🎊🍾🥂
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For anyone interested in #norovirus or biology of the murine norovirus receptor CD300lf, we deposited our CD300lf F/F mice @jacksonlab
https://t.co/1SpdQZOVhU They are available on live repository until 10/27 and then get frozen and $.@OrchardLab_Rob
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TRIM7 Act 2: Last year, postdoc @Wenchun_Fan published that TRIM7 is an antiviral protein that inhibits human enterviruses (PMID: 34062120). In an interesting twist, he now shows that that 3C protease from certain enteroviruses can cleave TRIM7. (1/4) https://t.co/soWOMp2Dqs
journals.asm.org
Enteroviruses are significant human pathogens that cause viral myocarditis, pancreatitis, and meningitis. Knowing how the host controls these viruses and how the viruses may evade host restriction is...
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New faculty position opportunity for the Division of Laboratory and Genomic Medicine in the Department of Pathology and Immunology at Washington University School of Medicine! @wusm_pathology
https://t.co/t7NIrhMcy6
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✨Speaker Announcement!!✨ The Department of Immunology at #UTSW will be hosting Dr. Elizabeth Johnson, PhD., Assistant Professor, Division of Nutritional Sciences, Cornell University , TOMORROW as part of their Excellence in Immunology Seminar Series.
Elizabeth Johnson, Microbiologist/Nutritional Sciences, https://t.co/0hrPBIkfp7
@CornellOFDD @CornellNutri @CornellCALS @Cornell @CornellResearch #cornellfaculty
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I’m looking for a PhD-level scientist to join my research group @Vir_Biotech. We work on exploratory projects in molecular virology and virus-host interactions across multiple viral pathogens with the goal to uncover new therapeutic approaches.
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Looking forward to our follow up studies on Trim7 in vivo and more collaborations with the awesome @baldridge_lab on viral evolution and screening with @JohnDoench
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