I am pleased to share our paper on axis formation in annual killifish, published in @sciencemagazine! See the thread below for a summary of the story.

New paper from my lab and @JShendure lab! Led by the brilliant @Zukailiu and @CXchengxiangQIU. We tackle a question: How do anterior and posterior progenitor cells cooperate to self-organize into an embryonic structure (termed AP-gastruloid)? (1/n) https://t.co/PjZ7ZpuhOV

Delighted to share the peer-reviewed version of our study now out in @GenomeBiology! We analyzed 64 chromosome-level genomes across 15 animal phyla and found that extensive genome rearrangements are the norm in bilaterians. https://t.co/09ZAyDMnzC

@UCBerkeley undergrads, there is still space in this course on the cellular, genetic, and developmental basis of evolution taught by Professor Nicole King and me this Fall. Find out why, as Dobzhansky, said "nothing in biology makes sense except in the light of evolution."

Some journals are claiming that you need to pay big $$ for gold open access to comply with NIH's new public access policy. FYI that is total bs. You can comply by depositing the Accepted Manuscript into PubMed Central on the Date of Publication without embargo. Pass it on.

Universities are not passive beneficiaries of government largesse. It is the federal government that depends on universities to conduct the research that keeps our nation healthy, safe and economically competitive.I discuss in the Washington Post. https://t.co/fQX5mwHu4f

Working on a gigantic gorgeous grant.

Molecular recording is an emerging field with exciting applications. In this review, @_Choi_Junhong and I outline major challenges that the community should address to fully realize the potential of this technology, and highlight promising directions that we are heading.

The more I look at this 3d rendering, the more it looks like an Ames window.

Bonus HCR 😛

Some B-roll from Eliza Barkan’s new preprint out of the Trapnell Lab. I think it will be a fin-tastic resource for the zebrafish community, especially for those trying to get a handle on the signaling pathways involved in specific cell types. https://t.co/mOYHVF0Hnh

I met a Searle Scholar who had done six rotations... talk about resilience.

This Is Just To Say I have used the CRISPR that was in the lab fridge and which you were probably saving for ethical purposes Forgive me I have edited a wolf into something more dire It now howls in fluent Latin and demands to be called Reginald

Is there any information on the details of gene editing used to make the “dire wolves?”

I’ve been preparing for their arrival

🚨ISRB Webinar - The Americas 🚨First one of the year! 🥳 Happening on January 17th, 12pm US East Coast Time, featuring Karen Echeverri from @MBLScience and Katy Loubnet-Senear from Phil Abitua's lab @Ohnolog @UW. Find all details at https://t.co/kfwpsG8XWZ

Opened a bottle of LB that no one in the lab could open. Good to know I’m still useful around the lab.

Ketamine Prevents Zebrafish from Giving Up by Acting on Non-neuronal Astrocytes @EngertLab @marcduque3 @alexbchen @MishaAhrens @BerglesDwi41784 @GesineSaher @HHMIJanelia @JohnsHopkins @harvardphysics @HarvardCCB @Caltech @ucdavis @HSCRB @harvardbrainsci https://t.co/9zLAbVJau1

Excited to host Nipam Patel this week—an OG of evo-devo!

But Why?

Very happy to share the first article from my postdoc work in the Tomancak lab! https://t.co/0gmwblw1Wb. We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)