Matthew Moll, MD, MPH
@MattMollpulmccm
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#pulmccm,#COPD,#jazz,#underservedmedicine,#genomics,#foodie. He/him/his. @BWHPulmCCM via @BMCIMres @HarvardChanSPH @PennState @michiganstateu
Boston, MA
Joined July 2015
1/2 New pub in @ATSBlueEditor We challenge the paradigm that all emphysema results from small airway disease. We show that most new emphysema arises from areas of high Mechanically Affected Lung (MAL) and in substantially higher proportion than areas of small airways disease.
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Thanks Helio for highlighting our work!
Published in @JAMA_current📣: The ability to predict #spirometry-defined #COPD was significantly better when a modified #lung function questionnaire score was used in combination with a COPD #polygenic #risk score. @MattMollpulmccm Read more⬇️
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Excellent course. Still remember taking it and was glad I did!
The Fellows Track Symposium is a two-day course held prior to the ATS International Conference and will allow adult and pediatric fellows to attend a special course covering cutting edge topics in the field of respiratory medicine! #ATS2025 Apply here: https://t.co/lfgB1qWcdc
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Happy #ManuscriptMonday! Check out this freshly published paper from @zhangjz07 and team (including Dr. Victor Ortega and senior author @MattMollpulmccm - hint for an upcoming CP Webinar 👀) https://t.co/XtfEXGtSJq
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Link to article: https://t.co/AmVdk186TL
@JAMA_current
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A chronic obstructive pulmonary disease (COPD) polygenic risk score enhances the identification of undiagnosed COPD beyond a conventional case-finding approach in the general population. https://t.co/6BGxeyrtYG
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Very excited to see our work using genetics for COPD case finding, an important step towards using genetic risk measures clinically. So proud of @zhangjz07 @BUPulmonary. Many thx @mikecho95 George O’Connor and coauthors. @BWHPulmCCM @ATS_GG
I’m excited to share this work hot off the press - genetic risk in case-finding for undiagnosed COPD. Grateful to my mentors @mikecho95 @MattMollpulmccm George O’Connor for the guidance! Many thanks to co-authors, @JAMA_current editors, and @BUPulmonary
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I feel very grateful and lucky to be recognized with this Young Physician-Scientist Award. Many thanks to @mikecho95 and Russ Bowler for the nomination as well as so many collaborators and mentors. Congrats to my colleagues too, jeong yun, nick bosch!
The ASCI is proud to announce our 2025 Early-Career Awardees! Click here for the complete list of awardees: YPSA: https://t.co/8JNkOWcdq5 E-Gen: https://t.co/oga7coPcTM Congratulations to our awardees and to the institutions they represent!
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Some very good news for people with asthma and COPD. The first new treatment for acute attacks in over 50 years—a monoclonal antibody vs interleukin-5 receptor-α—with efficacy in a randomized trial https://t.co/YW3PbKz0DF
@LancetRespirMed @SanjayResp @MonaBafadhel @kingsmedicine
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It’s really a privilege to mentor residents and fellows like Kevin Tong @BMCimRES who wrote this interesting review on PRISm with us. https://t.co/Dr47hvbc98 Check put the Table 1 he made summarizing the literature. Very helpful!
pubmed.ncbi.nlm.nih.gov
PRISm is a common spirometric abnormality which is robustly associated with negative outcomes. However, current knowledge gaps with respect to heterogeneity, specific etiologies, and longitudinal...
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Great talk @divayc
Glad to share our latest data on lithium as a disease modifying therapy for emphysema at the COPDGene meeting in Denver. @m_konigshoff @FrankS1956 @COPDFoundation @copd_inet @GOLD_COPD @COPD_research @PACCSM @PACCSM_fellows
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Lung Tissue Multilayer Network Analysis Uncovers the Molecular Heterogeneity of Chronic Obstructive Pulmonary Disease @atscommunity 🔗 https://t.co/c0V9N62NIp
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We also found in drug repurposing analyses that many agents previously implicated may only work in people with specific omics profiles, suggesting we can use omics to select patients for trials. A lot of help from coauthors @craig_hersh @peter4244 @mikecho95 @IainKon @zhangjz07
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Happy to share our work using genetics and transcriptomics together for subtyping COPD patients. We found heterogeneity within high risk groups, showing a group with greater lung function decline and another more severe group. Many thanks @eBioMedicine
https://t.co/lyrCygjsuG
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Our @AnnalsATS paper is in press examining rheumatoid arthritis risk factors with ILA in MESA & COPDGene. https://t.co/z0MxjNYuQ0
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Great talk on COPD and SDOH in genetically resilient individuals @accpchest 2024 meeting by @ajghosh @craig_hersh @mikecho95
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Thanks @pnatarajanmd
Very nice profile of physician-scientsts @KrishnaAragam @MGHHeartHealth & @MattMollpulmccm @BWHPulmCCM spanning specialized clinical programs & innovative research programs
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Excited for our protein risk score and mortality in individuals who smoke paper to come out: https://t.co/rloDkFovLZ Fun collaboration and interesting findings with respect to respiratory vs cardiovascular mortality. @mikecho95 @ytesfaig @manichaiku3044 @IainKon
nature.com
Scientific Reports - A protein risk score for all-cause and respiratory-specific mortality in non-Hispanic white and African American individuals who smoke
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Thank you for the invitation @AmyAttaway3. It was an honor to speak to this amazing group of physician-scientists!
What a great talk from @MattMollpulmccm on 'omics and precision medicine in #COPD research! Thanks so much for speaking at our COPD center meeting!! @CCF_PCCM @ClevelandClinic @CleClinicMD @atscommunity @ATS_GG #COPDGene
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