Alex Khromykh
@KhromykhAlex
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University of Queensland
Brisbane, Australia
Joined October 2013
Hydroxychloroquine did not have any effect on viral clearance in a RCT. High proportion with adverse events in HCQ arm but most mild.
medrxiv.org
Objectives To assess the efficacy and safety of hydroxychloroquine (HCQ) plus standard-of-care (SOC) compared with SOC alone in adult patients with COVID-19. Design Multicenter, open-label, randomi...
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It’s great to see that our paper on reverse genetics system for SARS-Cov-2 and other positive strand RNA viruses has been selected as Editor’s Highlights in “Microbiology and infectious diseases” web page of Nature Communications https://t.co/j0Z1VPyg9y.
nature.com
This page highlights recent articles on all aspects of bacteriology, mycology, parasitology and virology, covering the biology of pathogens, host-pathogen ...
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Amazing case report. The medicine of tomorrow. 5 week old boy admitted to NICU. Within 37 hours he had his whole genome sequenced, gene defect identified, treatment ordered and received by patient. Within 6 hr symptoms resolved. https://t.co/UYSJSURQHW
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Our paper on CPER-based reverse genetics system for SARS-COV-2 and other positive strand RNA is finally out in Nature Communications https://t.co/bkuKx5pwL6 big thanks to our collaborators at UQ, Uni Melb, Monash, and Queensland Health.
nature.com
Nature Communications - Here the authors describe a simple reverse genetics method that relies on overlapping cDNA fragments for generation of positive-strand viruses including SARS-CoV-2 and...
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Our complete mapping of mutations to #SARSCoV2 RBD that reduce binding by convalescent human plasma is out in @cellhostmicrobe ( https://t.co/F2sz3HL9tE). Right now E484K getting lot of attention, but I want to emphasize what our results suggest to keep eyes on in *future* (1/n)
cell.com
Greaney et al. map all mutations to the SARS-CoV-2 spike receptor-binding domain that reduce binding of longitudinally sampled polyclonal convalescent plasma. Despite heterogeneity within and between...
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More details now available for South African trial w/ Astra Zeneca vaccine, regarding B.1.351 variant. Table updated, data here: https://t.co/NekZxSDiL7 by @gksteinhauser
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This is now the third paper to find a very very good immune response after one shot of mRNA vaccine in people who had a previous SARS-CoV-2 infection. Time to discuss policy changes, @DrNancyM_CDC @CDCDirector!
medrxiv.org
The emergence of SARS-CoV-2 variants raises concerns about their resistance to neutralizing antibodies elicited from previous infection, or from vaccination. Here we examined whether sera and...
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The emergence of SARS-CoV-2 variants serve as a powerful reminder that viruses by their very nature mutate, and that science may need to adapt if they are to remain effective against them🔬 Statement from CEPI and our COVAX partners @gavi @WHO⏬ https://t.co/VkkEPbRlQL
cepi.net
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Great interview with Russell Basser from @CSL walking through the update on our @UQ_News #COVID19 #vaccine. While not the outcome we wanted, big shoutout to the Australian media for the accurate and balanced coverage, it means a lot to whole team who worked so hard this year! 🙏
The once-promising University of QLD COVID-19 vaccine has been scrapped after some trial patients returned false-positive test results for HIV. It’s forced the government to drop a billion-dollar commitment & seek millions more doses of other potential vaccines. #TheProjectTV
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It has been a real inspiration to see how much can be achieved with a great team of likeminded and highly motivated researchers. You guys gave it your best shot and I am sure you will rebounce back stronger than before.
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Thank you to our absolutely incredible team of scientists for their work on the #UQ/@CSLBehring COVID-19 vaccine, as well as our generous supporters and donors. While the vaccine will not be progressing, we're extremely proud of their hard work. Read more: https://t.co/GASLW4Z7go
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this makes sense, athough vaccinated people can do it themselves with other available antibody tests if they really want to know whether they are vaccinated with vaccine or with placebo
Roche is partnering with Moderna to include a COVID-19 antibody test in the mRNA specialist's ongoing vaccine trials, the Swiss drugmaker said on Wednesday, potentially demonstrating if the vaccine is working.
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We established work with SARS-CoV-2 virus and developed a simple and rapid way to manipulate viral genome. With #nhmrc funding we could apply this to figure out how the virus causes disease and develop new antiviral drugs #advanceaustraliacare #auspol #SaveOzScience @GregHuntMP
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We’ve had many years of successive @nhmrc funding for our research on medically important viruses which led to multiple reserch discoveries and development of vaccine candidates. Continuing @nhmrc funding is absolutely vital! #advanceaustraliacare #auspol #SaveOzScience
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1/ I am thrilled to share my first first author paper with #sciencetwitter! In our paper @cellhostmicrobe, we characterize mammalian RTP4 as a species-specific inhibitor of #flaviviruses. Some highlights:
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Research from the tenOever lab on #SARSCoV2 is showcased in this week’s @NewYorker. I could not be more proud of them. Shoutout to @daisyhoagz @rsmsllr @DBM003 @skyleruhl @BenjaminNilsson & all those not on Twitter
newyorker.com
At a laboratory in Manhattan, researchers have discovered how SARS-CoV-2 uses our defenses against us.
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Proud to have contributed @AnnikaKratzel It‘s amazing what structural biology can achieve @The_Ban_Lab @bode_lab
Structural basis of ribosomal frameshifting in SARS-CoV-2. Stimulatory viral RNA pseudoknot lodges at mRNA entrance channel, priming the ribosome to change the reading frame. Collaboration with @bode_lab, @ProfVolkerThiel, and Atkins labs. https://t.co/YeQtpzf9Vw
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Excited to share our latest work just published in @PNAS elucidating the molecular mechanism by which SARS-CoV-2 Orf6 inhibits Interferon signaling!
pnas.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic tha...
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The main hope is that antibody therapies could stop mild COVID-19 from becoming severe.
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Researchers at the Gobal Virus Network have been doing great work on COVID-19 response. This is one of the Spoltlights ( https://t.co/uefUfgqjPb) but there is a lot more, chek it out at https://t.co/wIxlFi6BJA.
gvn.org
International Science Innovation Week 2026 Registration Now Open Register Global Virus Network Welcomes New Centers of Excellence Across the Americas READ MORE Global Virus Network Launches Multi-C...
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