Kyle F. Biegasiewicz
@KFBChem
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Assistant Professor August 2023-present @EmoryChem Assistant Professor 2020-2023 @ASU_SMS Postdoc 2016-2019 @PrincetonChem PhD 2016 @URochesterChem
Joined February 2019
KFB Lab Alert: Our general biocatalytic platform for the oxidative rearrangement of indoles is now online at @ChemRxiv! Congratulations to @HJLChem and @sp3intermediate for leading this work with Sergio, Raina, Ana, Sophie, and John! https://t.co/7PMBifdyjJ
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Huge congratulations to the Ackerman-Biegasiewicz team on their work entitled "Harnessing Spectral Fingerprints to Predict Nickel Catalyst Performance"! LETS GO! https://t.co/JzusnnQlQ4
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Congratulations to team Ackerman-Biegasiewicz on their awesome new study entitled "Elucidation of Mononuclear Fe Photocatalysts for Visible Light-Induced Bond Homolysis (VLIH)" now available @ChemRxiv! Super cool study! https://t.co/Giq7tAHP6K
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I am incredibly excited to finally share our work on oxidative rearrangement of indoles, which is now available as a preprint on ChemRxiv! This submission marks a major milestone for me: my first, first author paper. Thank you to everyone who made this work possible.
KFB Lab Alert: Our general biocatalytic platform for the oxidative rearrangement of indoles is now online at @ChemRxiv! Congratulations to @HJLChem and @sp3intermediate for leading this work with Sergio, Raina, Ana, Sophie, and John! https://t.co/7PMBifdyjJ
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Ancestral Sequence Reconstruction to Accelerate Non-heme Iron-dependent Biocatalyst Engineering | ACS Central Science
pubs.acs.org
Nature provides access to biological catalysts that can expand the chemical transformations accessible to synthetic chemists. Among these, α-ketoglutarate, non-heme iron-dependent (NHI) enzymes stand...
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Check out @HJLChem and I’s recent report on using VHPO enzymes to prepare oxindoles and spiro-oxindoles! Excited to see this work out and help eliminate the need for hazardous halogenating reagents and harsh oxidants. Go team VHPO!
KFB Lab Alert: Our general biocatalytic platform for the oxidative rearrangement of indoles is now online at @ChemRxiv! Congratulations to @HJLChem and @sp3intermediate for leading this work with Sergio, Raina, Ana, Sophie, and John! https://t.co/7PMBifdyjJ
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CATNIP for the win! Read our newest work with the Gomes group- https://t.co/lILWdTxbVR
@Apatoneh @gabepgomes @daniil_boiko @AlisonNarayanUM
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So happy for this productive, fruitful and quite enjoyable collaboration. Something else in between is underway. Thanks @BAFrontanaU for showing us the electrosynthetic pathway. We are on the way to...
Great collaboration with @lab_fsp, Electrosynthesis vs Photoredox catalysis to generate complex spirocycles present in natural compounds via an alkoxy radical. In this case the total synthesis of Cephalosporolide F. Available here: https://t.co/ueeEbyseKS
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Amazing hire alert! Go Leah!
📣We are thrilled to welcome Dr. Leah Bushin as Assistant Professor of Chemistry at Stanford University! 🎉 Dr. Bushin’s research focuses on discovering and engineering nature’s specialized chemistry. Welcome, Dr. Bushin! Learn more: https://t.co/d7yQImxR0l
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📣We are thrilled to welcome Dr. Leah Bushin as Assistant Professor of Chemistry at Stanford University! 🎉 Dr. Bushin’s research focuses on discovering and engineering nature’s specialized chemistry. Welcome, Dr. Bushin! Learn more: https://t.co/d7yQImxR0l
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Long overdue post, but easily one of the coolest gifts to receive at the ACS Conference was THE Organic Chemistry text from author @XUChemProf! Thanks so much, Rick! It gave @BagPhos and I the opportunity to brush up on some mechanisms later! :)
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Using protein native backbone as ligand for organometallic catalysts without attaching ligands to protein is long sought after. Our MPAA ligand provides a perfect avenue to achieve this, showing high mono-selectivity: Nature Catalysis: https://t.co/c6NFzx8rfa
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Super cool to have our VHPO-catalyzed thioketal cleavage highlighted in OPRD! Thanks so much for the highlight! https://t.co/AyrygF08cX
pubs.acs.org
KFB Lab Alert: Our latest work applying enzymatic halide recycling to thioketal cleavage is now available @ChemRxiv! Congratulations to @ManiksharmaASR and Yue Li on this work! https://t.co/RUIRpPXMkB
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KFB Lab Alert: Our first efforts in biocatalytic chlorination of amines is now online @ChemRxiv! Congratulations to @EJGChem for leading this work with Sophie Barthel! GO VHPOs! https://t.co/TNFejA2ZUg
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It’s been an awesome trip to Washington, DC with the crew! Very proud of this wonderful team of scientists!
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🚨NEW PAPER ALERT📷@jeflip and @LipshultzSBU out in ACS Catalysis, feat. my rockstar undergrad Celeste Barefoot who worked in this during her REU! She's applying for PhD programs this fall!! 🔗below
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@FasanLab @UT_Dallas develops a new powerful method for skeletal editing of complex natural products at aliphatic C-H sites by combining site-selective and tunable enzymatic hydroxylation with chemical oxidation/ring expansion. Read on: •
onlinelibrary.wiley.com
A chemoenzymatic strategy is reported for enabling skeletal editing of a target molecule via ring expansion at the level of one or more aliphatic C─H sites. By combining P450-mediated site-selective...
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KFB Lab Alert: Congratulations to @ManiksharmaASR and @sp3intermediate for receiving outstanding poster awards at the Natural Products GRC! #coolbiocats
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Absolutely beautiful work from @CptingLab! Congratulations, Chi and team!
Our latest in @J_A_C_S, we report a general strategy to access antimicrobial sactipeptides by Markovnikov hydrothiolation of dehydroamino acids. Congratulations to Yiwei, Shuvendu, Steven and Yannik for their hard work!
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