Narayan Lab @ UMich
@NarayanLab
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Biocatalysis and complex molecule synthesis at the University of Michigan. Go BLUE! Go Chemistry! Now on bluesky @narayanlab.bsky.social
Ann Arbor, MI
Joined February 2016
CATNIP for the win! Read our newest work with the Gomes group- https://t.co/lILWdTxbVR
@Apatoneh @gabepgomes @daniil_boiko @AlisonNarayanUM
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Read our newest collaboration with the Hartwig group: Site-, Stereo-, and Chemoselective Enzymatic Halogenation of Terpenoids by a Substrate Masquerade | Journal of the American Chemical Society
pubs.acs.org
Enzymatic halogenation of C–H bonds is a promising approach to synthesize chlorine-containing compounds. However, few halogenases chlorinate C(sp3)–H bonds of molecules lacking a carrier protein, and...
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Ancestral Sequence Reconstruction to Accelerate Non-heme Iron-dependent Biocatalyst Engineering | ACS Central Science
pubs.acs.org
Nature provides access to biological catalysts that can expand the chemical transformations accessible to synthetic chemists. Among these, α-ketoglutarate, non-heme iron-dependent (NHI) enzymes stand...
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Uncovering the Origins of Selectivity in Non-Heme Iron Dioxygenase-Catalyzed Tropolone Biosynthesis | The Journal of Physical Chemistry B
pubs.acs.org
Non-heme iron (NHI) enzymes perform diverse oxidative transformations with precise control, which can be challenging to achieve with small molecule catalysts, such as the biosynthesis of tropolone....
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Profiling of Diverse Pyridoxal-5′-Phosphate Dependent Enzymes Reveals Promiscuous Aldolase Activity with (2-Azaaryl)methanamines | Journal of the American Chemical Society
pubs.acs.org
The elaboration of amine substrates through C–C bond-forming reactions is important in the synthesis of bioactive small molecules. Pyridoxal-5′-phosphate (PLP)-dependent enzymes have emerged as...
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A team from @UMich and @CarnegieMellon has developed CATNIP for chemists — a data-driven platform that removes a major barrier to wider adoption of #biocatalysis, making greener chemistry more accessible. Read more: https://t.co/apnjjpLWNy
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I’m thrilled to share that I will be joining the Department of Chemistry at the University of Rochester as an Assistant Professor! So thankful for this opportunity and excited about expanding the field of biocatalytic synthesis!
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What Do You Collect? New Episode Some of the Biggest Brands in the Collectible Industry on this S2 Ep1 Podcast Mike Gio @SCN_Pod Billy Lesnak @SCCTradingCards & @BlockchainSteve of @NBATopShot Watch on: WhatDoYouCollectPodcast .com & @collctn_connctn YouTube Channel
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The application deadline has been extended to April 11th! For more information on the workshop look here - https://t.co/tTY95Pr2IY
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CATNIP – our collaboration with the @NarayanLab under the NSF Center for Chemoenzymatic Synthesis – was nicely covered on @cenmag! one of the coolest works we’ve been involved in, headed by the one and only @daniil_boiko on our side. https://t.co/H9uk056Hno
cen.acs.org
Machine learning model Catnip helps chemists find biocatalysts to try in synthesis
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Calling everyone interested in learning biocatalysis! Come to the Narayan lab to learn the biocat basics. Please apply here - https://t.co/U9YRcCyK0E
#Biocat #GoBlue
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Go Eunjae go!!
Check out our latest article by @EunjaeShim1 now published in @ChemicalScience on label ranking, introduced as an efficient #MachineLearning algorithm to predict high yielding and effective reaction conditions for a variety of substrates. https://t.co/8Ja4Qa5fyJ
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