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Juan Alvarez Profile
Juan Alvarez

@JuanAlvarezDom

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Assistant Professor @PennCDB @IRM_UPenn @PennIDOM @chronosleepinst, asking How circadian rhythms shape islet development and diabetes

Philadelphia, PA
Joined June 2019
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@JuanAlvarezDom
Juan Alvarez
3 months
What if the AI could write the paper for you? 🚨Spoiler alert: it does! We've designed a spatial transcriptomics AI agent to chart hPSC-pancreas maturation in vivo, and report on interesting biology, autonomously
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@JuanAlvarezDom
Juan Alvarez
23 hours
Today @ 1pm EST - spatial transcriptomics AI agent for the non-CS expert, looking forward!.
@JuanAlvarezDom
Juan Alvarez
11 days
Democratizing Spatial Tx-omics webinar, with @ganoopyliujia @WangXiaoLab's @wenbowang11 @ZuwanLin - Looking forward this July 17!
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@JuanAlvarezDom
Juan Alvarez
11 days
Democratizing Spatial Tx-omics webinar, with @ganoopyliujia @WangXiaoLab's @wenbowang11 @ZuwanLin - Looking forward this July 17!
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@JuanAlvarezDom
Juan Alvarez
14 days
RT @TheModzLab: Hey everyone! Come join me in Mexico to hear about retrotransposons like Endogenous Retro Viruses that have switched sides….
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@JuanAlvarezDom
Juan Alvarez
22 days
RT @ganoopyliujia: Our latest work is on the cover of @Nature (June 26, 2025)! Even more special: the stunning illustration was hand-drawn….
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@JuanAlvarezDom
Juan Alvarez
23 days
RT @ChenShuibing: Happy to share the exciting news that Jeya’s paper on ChemPerturb-Seq is online @JeyaVandana @TPCB_NYC @WCMSurgery @WCMCG….
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@JuanAlvarezDom
Juan Alvarez
23 days
RT @JeffreyRMillman: Big #T1D news! Vertex has published their phase 1–2 trial of stem cell-derived islets (VX880, now called zimislecel).….
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@JuanAlvarezDom
Juan Alvarez
1 month
RT @isletbiologylab: Ives et al. applied top-down proteomics to evaluate proteoforms from human islets treated with cytokines. They identif….
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@JuanAlvarezDom
Juan Alvarez
1 month
RT @isletbiologylab: Swensen et al. aimed to identify in situ proteome alterations of the human islets during stage 1 #type1diabetes throug….
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@JuanAlvarezDom
Juan Alvarez
1 month
RT @LabZhu: This is a very good review on ~12h biological rhythms. Biological rhythms: Living your life, one half-day at a time | npj Biolo….
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@JuanAlvarezDom
Juan Alvarez
1 month
Good things come in two's: celebrating couple graduates, grants, preprints. Couldn't have imagined a better team of mavericks!
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@JuanAlvarezDom
Juan Alvarez
1 month
RT @UMassDiabetes: The @BreakthroughT1D Barbara Dewey Cammett Center of Excellence, led by Dr. David Harlan, consists of scientists from @U….
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@JuanAlvarezDom
Juan Alvarez
2 months
RT @IsletSeries: Don't miss the last talk of the year! Yuval Dor on RNA editing
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@JuanAlvarezDom
Juan Alvarez
2 months
RT @WeitzmanLab: Listen to @davidrliu explain why it is so important to support basic science.
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@JuanAlvarezDom
Juan Alvarez
2 months
RT @UPENN_ITMAT: Tissue-specific loss of #Tregs and rise of stem-like CD8+ T cells prior to the onset of #TypeIDiabetes may offer promising….
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@JuanAlvarezDom
Juan Alvarez
2 months
RT @DanielKessler10: Pride Month Celebration - June 9.@LTBGS_Penn @PennCDB @CAMBUpenn @pennbgs @RTAatPennMed
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@JuanAlvarezDom
Juan Alvarez
2 months
EDN3 expression preserves stem cell-derived β cell identity and function in hypoxia, offering a path to improve transplant outcomes.
@isletbiologylab
Islet Biology Lab - UMH
2 months
Wang et al. show that, unlike other stem cell-derived endocrine cells, there is a progressive loss of cell identity and metabolic function in stem cell-derived β cells when exposed to hypoxia.
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@JuanAlvarezDom
Juan Alvarez
2 months
RT @NIHFunding: Notice of Short-Term Extension to Early-Stage Investigator (ESI) Eligibility Period
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@JuanAlvarezDom
Juan Alvarez
2 months
RT @PennMedCSO: .@kiranmusunuru (@PennGenetics/ @PennCardiology), @AhrensNicklas (@CHOP_Research) & colleagues raced against time to delive….
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@JuanAlvarezDom
Juan Alvarez
2 months
RT @LabZhu: Interesting work. 12h rhythms of lipid metabolism in the Drosophila fat body, independent of the circadian clock. Circadian cl….
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@JuanAlvarezDom
Juan Alvarez
2 months
RT @HHMINEWS: A baby named KJ, who was born with a rare genetic disorder – CPS1 deficiency – is healed thanks to doctors at the @ChildrensP….
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