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HIRN Profile
HIRN

@HIRN_CC

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Human Islet Research Network (HIRN) is a network of research consortia, each focused on a specific T1D biological challenge. A NIH NIDDK Funded Initiative.

Joined January 2016
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@HIRN_CC
HIRN
2 months
We are excited to share the results of the HIRN Data Scholars Leveraging Multi-Modal Human Islet Research Network Knowledge (LINK) competition. Please join us in congratulating Dr. Matthew Ishahak and Dr. Liu Wang on their selection as awardees.
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@HIRN_CC
HIRN
3 months
Click link below for direct access to all study resources https://t.co/rSuLE6EgJ9
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@HIRN_CC
HIRN
3 months
Recently Curated #HIRN Resources Patch-Seq datasets (GSE270484 and more) produced in a study revealing a novel pathway by which TMEM55A regulates α-cell exocytosis by manipulating intracellular PI5P level and the F-actin network. PMID39763967.
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@HIRN_CC
HIRN
3 months
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@HIRN_CC
HIRN
3 months
Recently Curated #HIRN Resources Antibodies targeting MX1 and more used to provide the first evidence that the m6A epigenetic modification machinery controls CVB amplification in human pancreatic beta cells. Click link in comments below for direct access to all study resources
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@HIRN_CC
HIRN
3 months
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@HIRN_CC
HIRN
3 months
Recently Curated #HIRN Resources New datasets (GSE24317, GSE228087, and more) produced in a study showing that LRH-1/NR5A2 activation induced a genetic and immuno-metabolic reprogramming of T1D immune cells. Click link in comments below for direct access to all study resources
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@HIRN_CC
HIRN
4 months
Applications due October 15 (5pm Pacific) No additional funding is provided, but members gain access to a vibrant research network and professional development opportunities. For details or to apply visit our website:
hirnetwork.org
The Human Islet Research Network (HIRN) is now accepting applications for its Associate Membership Program, designed to welcome investigators with active, peer-reviewed funding who are conducting...
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@HIRN_CC
HIRN
4 months
This program offers opportunities to collaborate with HIRN consortia, present research at annual meetings, and engage in interdisciplinary discussions that advance the field of islet biology and diabetes research.
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@HIRN_CC
HIRN
4 months
HIRN Associate Membership   Now accepting applications for its Associate Membership Program, designed to welcome investigators with active, peer-reviewed funding who are conducting research aligned with HIRN’s mission to understand and restore islet function in type 1 diabetes.
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@HIRN_CC
HIRN
5 months
Recently Curated #HIRN Resources Human insulin and somatostatin antibodies used in a study to show a SARS-CoV-2 spike S1 recombinant protein activates pericytes and induces capillary constriction. PMID39715591. Click link in comments below for direct access to resources
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@HIRN_CC
HIRN
8 months
Recently Curated #HIRN Resources Dataset (GSE252614) produced in a study showing that NKX2-2 based nuclei sorting on frozen human archival pancreas enables the enrichment of islet endocrine populations for single-nucleus RNA sequencing Click link in comments for all resources
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@HIRN_CC
HIRN
8 months
HIRN Funding Announcement: Data Scholars Awards A new funding initiative to support the use of existing HIRN datasets and resources to explore unique and innovative hypotheses designed to accelerate breakthroughs & advances in T1D research. https://t.co/8G1Gptx0iB
hirnetwork.org
The Human Islet Research Network (HIRN) announces a new funding initiative to support the use of existing HIRN datasets and resources to explore unique and innovative hypotheses designed to acceler...
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@HIRN_CC
HIRN
9 months
Recently Curated #HIRN Resources Antibodies targeting CD44, CD99, and more used to show that the IsletTester mouse will enable the study of human islet biology over time and under different physiological conditions @KaestnerKlaus Click link in comments for access to resources
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@HIRN_CC
HIRN
9 months
Recently Curated #HIRN Resources Datasets (GSE266291 & GSE266405) produced in a study that identified that differentially accessible regions overlap with T2D-associated variants in a sex- and cell type-specific manner Click link in comments below for direct access to resources
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