Samantha Morris
@morris_lab
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Reprogramming and single cell biology @BrighamWomens @harvardmed. Robertson Investigator @NYSCF. Associate Ed @Dev_journal. Co-founder - CapyBio
Boston, MA
Joined May 2015
At last! Happy to share our paper on CellOracle – a computational method for dissecting cell identity via network inference and in silico gene perturbation, led by the amazing @kenjikamimoto68:
nature.com
Nature - A machine-learning-based strategy called CellOracle combines computational perturbation with modelling of gene-regulatory networks to analyse how cell identity is regulated by...
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Stop guessing Incoterms. Grab our free quick-reference sheets and know exactly who owns cost + risk on every move. → Click for free download
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3 weeks to go until registration closes for our Single-Cell Technologies Conference! Join leading experts to discuss dynamic technological developments, emerging technologies & their potential for catalyzing future biomedical breakthroughs & precision medicine strategies!
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New “discrete state” model of hematopoiesis published in Nature Immunology. https://t.co/E1bSt1cGN7 We propose a hierarchical model of hematopoiesis where stable “discrete states” serve as key regulatory nodes. With @nsalomonis @morris_lab @BioLegend @CytekBio @NIH @NIDDKgov and
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New in Nature Reviews Genetics: my Review on how advanced genomic technologies are redefining cellular reprogramming: mapping trajectories, dissecting chromatin dynamics, + lineage tracing & synthetic circuits to push the boundaries of cell identity. https://t.co/8NBM5ohxkJ
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Morris Lab vs @FD_Camargo Lab ⚽️ match for the glory of CellTag vs LARRY. This one was a 'friendly'… next time, reagents are at stake.
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How I’ll always remember him... full of humour, curiosity, and kindness. Cambridge party, many years ago.
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Saddened to hear of John Gurdon’s passing. A brilliant scientist, generous mentor, and endlessly curious. When he examined my PhD viva in 2006, he’d just come from doing experiments at his bench - at 73. He shaped so many careers, including mine:
cam.ac.uk
Sir John was a visionary in the field of developmental biology, whose pioneering work on nuclear transfer in frogs addressed one of the most fundamental questions in biology: whether genetic
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Thank you @IdoAmitLab, @AlejoFraticelli , @leilaperie for putting such a fantastic conference together! Can't wait for the next #EMBO Lineage Tracing Workshop
What an incredible #LineageTracing meeting! Huge thanks to all participants and speakers for creating such an inspiring environment. Looking forward to seeing you next year in San Sebastián- more details coming soon!
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🧬 Data: GEO GSE241627 📦 Code: https://t.co/pcs7Gjq7qr 👏 Huge shoutout to @RivGuillermo and @mle_butka for leading this project.
github.com
Relevant data and code for reproducing analysis of in vivo lineage tracing adipocyte precursors in skin - morris-lab/adipogenesis-reproducibility-repo
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We identify a previously unrecognized immature preadipocyte population and show that Sox9 links proliferation with fate commitment. Cross-depot transplants reveal how both niche and intrinsic identity shape adipogenesis.
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Skin fat plays by its own rules. We trace lineages (CellTagging), classify cell identity (Capybara), and model fate decisions (CellOracle) in our new Cell Stem Cell paper. It’s not a linear path. 🔗 https://t.co/8MJXU7Vd0Q
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Time to mark our calendars moving for our 3rd "Probing Human Disease using Single-Cell Technologies" @Fusion_Conf taking place March 1-4, 2026 in beautiful Playa Mujeres, Mexico!! Our first 15 speakers are already on board and Early Bird and Talk submissions on Sept 3rd! Dont
Amy is looking forward to reuniting with familar faces, and welcoming new ones to the upcoming Single-Cell Technologies conference next year! A reminder that this meeting has sold out BOTH times, so do not delay getting registered and joining @iannisaifantis1 @satijalab and
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Absolutely thrilled to share with you the final version of EPIclone, out now (open access) in @Nature. This has been an amazing collaboration with the lab of Lars Velten (@larsplus) at @CRGenomica
https://t.co/BI12Ir7fyz
nature.com
Nature - The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell...
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📢 WEBSITE LIVE! Very excited to announce the date for the 3rd Probing Human Disease using Single-Cell Technologies Conference! Chaired by the fantastic @iannisaifantis1 , @morris_lab & @satijalab🌞The 3rd meeting in this wonderful series will be hosted in Playa Mujeres, Mexico
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Had a great conversation with Craig and Thomas on Discover Your Star! We discussed how cells adopt and change identity, the challenges of reprogramming, and the twists and turns of scientific discovery that shape new ideas.
Persistence is an extremely valuable skill. Never taking no for an answer.“ – Dr. Samantha Morris @morris_lab
https://t.co/SSmfy7Wyuo
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🚨 We're hiring! 🚨 The Morris Lab @BrighamWomens & @harvardmed is looking for a Research Technician to join our team! 🔬 Focus: Lineage reprogramming & genomic tech development 🧫 Skills: Molecular biology, cell culture, mouse work 📍 Boston, MA https://t.co/I1APZMfP8l
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If this were easy, it wouldn't be worth doing. – Sam Morris @morris_lab on the Night Science Podcast now also on YouTube. https://t.co/yl7RU52APJ
@nightsciencepod
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I’m beyond thrilled to share that I successfully defended my thesis last Wed! Heartfelt thanks to my incredible mentor @morris_lab , beloved Morris Lab members, and everyone who cheered me on throughout this journey. It still feels like a dream, but I’m officially Dr. Yang! 🎓🥳
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Congratulations Dr. Yang @bioyangxue and Dr. VanHorn @SadieVanHorn1 🎓🍾💐. I’m so proud of you both!
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