Jonathan Bayerl
@JonathanBayerl
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EMBO/Sandler PBBR/BARI postdoc at @UCSF. Stem cell biologist interested in early development/heterochrony/longevity using eusocial super agers (naked mole-rats)
San Francisco, CA
Joined September 2023
I am honored to express my opinion on this new approach in fertility and reprogramming -exciting times ahead!
Funktionsfähige Eizellen aus menschlichen Hautzellen erzeugt: Portland – Ein Forschungsteam aus den USA hat in einer Proof-of-Concept-Studie erstmals gezeigt, dass sich aus menschlichen Hautzellen befruchtbare Eizellen erzeugen lassen. Die in Nature… https://t.co/x3I0dieOIG
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Finally .. incredible much awaited wok on deriving avian naive ESCs “Derivation of embryonic stem cells across avian species” https://t.co/aDMKPB6ORv
nature.com
Nature Biotechnology - Embryonic stem cells for chicken and seven other avian species are derived.
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Scholarship, abstract and early registration deadlines: 1. Scholarship/Short Talk Abstract Deadline: October 21, 2025 (11:59pm MST) 2. Early Registration: December 18, 2025 (Save $200 – 11:59pm MST) 3. Poster Abstract Deadline: January 27, 2026 (11:59 MST)
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Scientists have for the first time ever filmed a crucial step that leads to new human life – cracking open a 'black box' of early development. @ojosnegros_sam @IBECBarcelona
https://t.co/k1cJGVgx5R
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A time-lapse film offers a glimpse of a hidden milestone of human development: the moment when the newly formed embryo latches onto the uterine lining. Watch a human embryo implant itself — with brute force https://t.co/dkXCZsV10B
nature.com
Nature - Video provides an up-close look at a human embryo plunging into tissue that simulates the uterine lining.
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Just mind-blowing in every way!
A time-lapse film offers a glimpse of a hidden milestone of human development: the moment when the newly formed embryo latches onto the uterine lining. Watch a human embryo implant itself — with brute force
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1/n Fun journey continues: Our new @CellStemCell paper out on how the Inherent & Dormant Plasticity of mouse naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells".
cell.com
Hanna and colleagues show that signaling pathway modulation amplifies the inherent flexibility of genetically unmodified mouse naive PSCs to adopt extra-embryonic cell fate potential. This endows...
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Now online! Unraveling mitochondrial influence on mammalian pluripotency via enforced mitophagy
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Excited to share our new study in Cell—congrats to Daniel, co-authors, and our collaborators in the @PeterLyLab What began as pure curiosity led to a tool for modulating mitochondrial abundance in vitro and in vivo. A new direction for the Wu lab begins!
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Stem cell-based models of early human development Read this Development at a Glance Article by Lizhong Liu @LLizhong and Jun Wu @leo_jwu: https://t.co/4HTZchxQtZ
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The renowned Weizmann Institute of Science in Israel is touring through USA looking for outstanding postdocs and PhD students! As one of their PhD alumni I can only highly recommend this center of innovation, groundbreaking discoveries and bad-ass science!
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The ISSCR remembers Roger Arnold Pedersen, PhD, a pioneering figure in stem cell biology and developmental genetics whose groundbreaking work has significantly shaped the understanding of early mammalian development and regenerative medicine. https://t.co/kyaZ1QwxPT
isscr.org
The ISSCR is saddened to learn of the death of Roger Arnold Pedersen, PhD, a pioneering figure in stem cell biology and developmental genetics whose groundbreaking work has significantly shaped the...
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Truly one of the most exceptional scientists I've ever had the pleasure of meeting. Congratulations @JonathanBayerl on your O-1A! You're saving our declining fertility, one stem cell at a time. Proud to support you @lighthousehq_ 🇺🇸
O-1A visa approved! I am humble to be holder of the U.S. visa for people with extraordinary abilities in science😇😇 Thanks to @minney_cat @lighthousehq_ for their outstanding support and guidance in handling my application super swiftly and efficiently! I highly recommend them!
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O-1A visa approved! I am humble to be holder of the U.S. visa for people with extraordinary abilities in science😇😇 Thanks to @minney_cat @lighthousehq_ for their outstanding support and guidance in handling my application super swiftly and efficiently! I highly recommend them!
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A new Naked Mole-Rat reference genome by @DSokolowski95 @wilson_md and co. I am glad to have contributed with @DJ_Laird to this wonderful piece of science of the unique NMR biology. This is just the start of an upcoming wave of NMR landmark papers including my own so stay tuned!
Definitely an exercise in delayed gratification. Naked mole-rats have emerged as a model organism due to their suite of unique traits. We built a reference-grade genome assembly and annotation for the NMR by integrating long-read genomics, epigenetics, and evolutionary genomics.
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Axolotls stop aging after four years—could studying them help humans live longer? https://t.co/JJRj4JlXCh via @NatGeo
nationalgeographic.com
The feathery gilled pink salamanders stop aging early and can regenerate their limbs. Studying them could be the next step in the journey to unlocking effective anti-aging treatments in humans.
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Our latest out today @Nature! We revisit a century-old theory and show that metabolic gradients work hand-in-hand with genetic&signalling instructions to shape the embryo. Glucose isn't just an energy source, it acts as a major conductor of the body plan🍬 https://t.co/mfx6Hk7nma
nature.com
Nature - Two waves of glucose metabolism provide distinct ERK-mediated cellular signals during gastrulation, which regulate cell fate and specialized cellular functions that are necessary for...
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Cool work by @bulutkarslioglu & @NRivron showing diapuse like state can be induced in naive & intermediate naive-like (RseT), but not primed, human PSCs & in blastoids @CellCellPress mTOR activity paces human blastocyst stage developmental progression
cell.com
The timing of human blastoid post-implantation development can be paced down by inhibition of mTOR, which elicits a tissue-specific response similar to mouse in vivo diapause.
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We are excited to share our work on characterizing and overcoming interspecies PSC adhesion incompatibility to improve interspecies chimerism, published in @CellStemCell today. (1/10) @edbinshtok @leo_jwu @LLizhong @SeiyaO1224 @leqianyu
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DNA methylation in mammalian development and disease https://t.co/XShWAoBisC
#Review by Zachary D. Smith @YaleMed, Sara Hetzel (@hetzel_s) & Alexander Meissner @MPI_MolGen Free to read here: https://t.co/MJWXDPXcyQ
@maxplanckpress
nature.com
Nature Reviews Genetics - In this Review, Smith et al. describe DNA methylation landscapes that emerge over mammalian development and within key disease states, as well as how different...
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