Johannes Backs
@JohannesBacks
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Professor of Experimental Cardiology at Heidelberg University, Fan of Healthy Hearts, HDACs and Borussia Dortmund
Heidelberg, Deutschland
Joined December 2017
Congrats, Doris! And thank you that we could contribute to this. The heart undergoes wasting as skeletal muscle and fat do.
Amazed to share our new study published in @CellCellPress revealing how the liver contributes to weight loss in cancer via disruption of a circadian regulator and secretion of catabolic factors. Big thanks to @FiskerSchmidt, S. Herzig, @BerrielDiaz 🧵👇 https://t.co/2fvK9ExTMO
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@MarkEPepin et al show that genetically disrupting a single mitochondrial enzyme #NNT lowers cardiometabolic #HF & reduces oxidative stress in the heart. Learn about a therapy for #HFpEF at https://t.co/qLCbgvmQZl
@JohannesBacks @hohl_mathias @AnjaKarlstaedt @ChristophMaack
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Maarten van den Hoogenhof found a specific way to improve cardiac function in RBM20 cardiomyopathy. CAMK2 inhibition might become the first tailored therapy for a Dilated Cardiomyopathy (after mavacamten for Hypertrophic Cardiomyopathy):
biorxiv.org
Although heart disease can arise from different etiologies, current treatment is not tailored to the different underlying causes but is rather a one-size-fits-all approach. Importantly, not all...
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Glad this out. Congrats to Mark Pepin. He found that mitochondrial NNT drives diastolic dysfunction in cardiometabolic HFpEF. This directed us to ROS-dependent mechanisms underlying HFpEF. More to come … https://t.co/MsofXcOVBr
ahajournals.org
BACKGROUND: Clinical management of heart failure with preserved ejection fraction (HFpEF) is hindered by a lack of disease-modifying therapies capable of altering its distinct pathophysiology....
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The newly established Helmholtz Institute for Translational AngioCardioScience (HI-TAC) is looking for two Junior Research Group Leaders in the field of AngioCardioScience! Please feel free to reach out and help spread the word! Apply now: https://t.co/bT5LwagcVo
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The newly established Helmholtz Institute for Translational AngioCardioScience (HI-TAC) is looking for a Scientific Coordinator! Please feel free to reach out and help spread the word! Apply now: https://t.co/CzT3vKfb1d
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Repost and spread the word
We recruit Junior Group Leaders at the new Helmholtz-Institute for Translational AngioCardioscience (HI-TAC): 5+4 years. Work in the Heidelberg-Mannheim area in collaboration with the MDC Berlin! Apply now or latest Jan 6!
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We recruit Junior Group Leaders at the new Helmholtz-Institute for Translational AngioCardioscience (HI-TAC): 5+4 years. Work in the Heidelberg-Mannheim area in collaboration with the MDC Berlin! Apply now or latest Jan 6!
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Congratulations, Matthias Hentze! EMBL Director Matthias Hentze is the 2025 recipient of the Otto Warburg Medal, regarded as Germany’s highest award for biochemists and molecular biologists. https://t.co/C1jXD0K4uj
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Two days left to apply as HI-TAC Science manager. Coordinate exciting science in the field of AngioCardioScience at Heidelberg University (Mannheim/Heidelberg) in partnership with MDC Berlin:
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I am thrilled to announce the release of our initial preprint showcasing the involvement of resident macrophages and cardiomyocytes in ECM remodeling, facilitating cardiomyocyte migration, and promoting heart regeneration. https://t.co/PUyrv0XrHd
biorxiv.org
Despite numerous advances in our understanding of zebrafish cardiac regeneration, an aspect that remains less studied is how regenerating cardiomyocytes invade, and eventually replace, the collagen...
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Impressions of Day 4 of #EMBOCardioBiology 📸 The conference ended with keynote speaker Eric N. Olson @Transactivator on genetic correction of heart and muscle disease and @JohannesBacks awarded the prizes for best posters 🎉🏆
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Spectacular turnout and discussion @EMBLEvents #EMBOCardiobiology, @JohannesBacks! Such a privilege learning and presenting to this interactive group (and also seeing old friends). I’ll keep coming back to this one!
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My mind is racing with excitement. We had the inaugural ‘The new Cardiobiology meeting’ at EMBL Heidelberg. Thanks to EMBO for support. Thanks to all participants onsite and virtually for making this possible. #EMBOCardioBiology
We just wrapped up an incredible journey at #EMBOCardioBiology and are full of appreciation 🙏🤩 A big thanks to everybody for a great conference programme and establishing such a vibrant community ✨ Looking forward to more opportunities to learn, grow, and collaborate.
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I am humbled and so pleased that cardiovascular world experts came to Heidelberg this week to the 1st International CRC1550 Meeting to discuss science with our trainees. High quality meeting which needs to be repeated in 2026. #CRC1550
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Welcome to #EMBOCardioBiology 🙌🎉 Hope you will enjoy the next 4 days packed with brilliant sessions about cardiovascular research. The conference was opened by @JohannesBacks followed by the keynote from Christine Mummery about hiPSC models.
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Do you want to confess with myocardial macrophage monks? Come to this conference in a Bavarian monastery! All religions welcome. 👇 II. Cardioimmunology congress from June 26th, 2024 to June 28th, 2024 ⛪️🔥❤️🔥⛪️ https://t.co/8fuEdThfzu
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