Florian Constanty
@FlorianConst
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Yesterday we wrapped up a workshop "Genome editing in zebrafish: knock-ins and their applications". A huge THANK YOU to EVERYONE who joined us for very rigorous and stimulating scientific discussion throughout the workshop! (1/5)
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Maarten van den Hoogenhof found a specific way to improve cardiac function in RBM20 cardiomyopathy. CAMK2 inhibition might become the first tailored therapy for a Dilated Cardiomyopathy (after mavacamten for Hypertrophic Cardiomyopathy):
biorxiv.org
Although heart disease can arise from different etiologies, current treatment is not tailored to the different underlying causes but is rather a one-size-fits-all approach. Importantly, not all...
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Dive into our latest review, with @BailinW40848 and @ABeisaw, and explore the fascinating ways cell-cell interactions power heart regeneration! https://t.co/kcl6Iboa74
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Check out the latest issue of @CircRes with our Echo-Guided IR Method on the cover ♥️ 🥢
@CircRes May 9th Issue is Out! https://t.co/IiX6g6rOKd Cover: Representative IF staining of endothelial cells (magenta), inflammation (yellow), & WGA (green) in a 4-chamber view of a heart 7 days after Echocardiography-Guided Induction of I/R;nuclei-blue.
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New research from Dr. Arica Beisaw (@ABeisaw) and team! 👏 Dr. Florian Constanty, Bailin Wu, and colleagues provide insight into the mechanisms underlying #cardiomyocyte invasion of the #collagen-containing injured tissue during cardiac regeneration. https://t.co/HfoI9os7s3
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I am excited to share my first author paper published in Nature Communication ! I am thankful to @ABeisaw for giving me the chance to work in her lab and believe in me. https://t.co/NZrWYDNDMv
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Interested in #cardiac_regeneration, #zebrafish, #aging, and the #immune_response? We are looking for a candidate to apply for a PhD opportunity from the CARe graduate school @CareGraduate in Toulouse!
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Super excited to share that our manuscript is finally OUT @CellSystems!!🚨 Cold and hot fibrosis define clinically distinct cardiac pathologies. https://t.co/pZhWBCyPtG🧵(1/)
cell.com
Miyara et al. identify two types of fibrosis in cardiac pathologies: “hot fibrosis,” involving macrophage-myofibroblast interactions in chronic injuries, and acute-injury-driven “cold fibrosis,”...
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We recruit Junior Group Leaders at the new Helmholtz-Institute for Translational AngioCardioscience (HI-TAC): 5+4 years. Work in the Heidelberg-Mannheim area in collaboration with the MDC Berlin! Apply now or latest Jan 6!
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Inflammation droves a pro-fibrotic state in heart failure via chromatin remodeling. Another masterpiece by @m_alexanian and friends @GladstoneInst
nature.com
Nature - Conditional deletion of the transcriptional co-activator Brd4 in infiltrating Cx3cr1+ mouse macrophages ameliorates heart failure and substantially reduces fibroblast activation.
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P-bodies; sites of excess RNA accumulation, or actors in gene regulation? We tackle this long-held question by looking at the RNA content in p-bodies across the cell cycle. Feedback much appreciated. https://t.co/E7bCrLjmz6
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Congratulations to the best rapid fire presenters Celine Müller and Mike Morneweg. Thank you for sharing your interesting data 👏. @dzhk_germany @YoungDZHK @MichaelMolitor6 @SoniaSingh0105 @SFG_Ffm
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Master's, PhD, etc: Don't miss this opportunity to sign up for our (free) developmental biology course in Paris!!! All are welcome. As usual, we have an amazing speaker lineup for you! @DoetschLab @PavelTomancak @CorderoLab @Epi_Nath @MarieBreau1 @dudin_o @stemdevevo...
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📢Join us @institut_curie! Listen to outstanding scientists working on developmental biology and stem cells. Send your students and postdocs, it's free! @DoetschLab @PavelTomancak @Epi_Nath @CRougeulle @dudin_o @_CellySally_ @MeilhacSigolene @VallierLab @NVastenhouw @jvveenvliet
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Dear Young DZHK members: a few days left to submit your abstract & to join the 10th DZHK Retreat in Frankfurt in September! 👉 https://t.co/c5waq2SeqZ Meet your Young DZHK peers, present your own research, learn about newest findings & celebrate with us! @dzhk_germany
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DZHK-researchers @Ralf_Gilsbach @Patrick_lrt from Heidelberg @uniklinik_hd are investigating how well epigenetic silencing with the AAV-CRISPRi system works in heart cells. It could become a standard method for research into cardiovascular diseases.
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Our #SpotlightZebrafish this week is a special 🌟double feature🌟highlighting Dr. Florian Constanty (@FlorianConst) and Bailin Wu (@BailinW40848) of the @ABeisaw Lab @UniHeidelberg. They investigate the molecular and cellular mechanisms regulating cardiomyocyte invasion of
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🚀Interested in applying for a #MarieSkłodowskaCurie #Postdoctoral Fellowship? Join our lab at the intersection of developmental biology and immunology at @institut_curie! Explore how microbes and the immune system interact to shape gut development and physiology!🧬🔬 Please RT!
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I have a funded postdoc position to work on the #immune response during #zebrafish #regeneration. If interested, please contact me through the provided email address. Those interested in doing a PhD are welcome to contact me as well. Please share and RT.
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