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Joseph Derosa Profile
Joseph Derosa

@JDerosaChem

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1K
Following
2K
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69
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954

Assistant Professor @BUChemistry | Member of @derosalab | transition metal and (electro)catalysis enthusiast | NYC born and raised | (he/him)

Boston, MA
Joined August 2012
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@JDerosaChem
Joseph Derosa
6 months
Congrats to Brett and Jillian on this incredibly powerful e-SNAr strategy! Synthetically enabling, extremely robust, and highly energy-efficient with as low as 20 mW of power at 50 mmol scale with a proposed uphill ET-promoted redox chain mechanism. Dump, stir, ⚡️ #chemtwitter
@derosalab
Derosa Lab
6 months
SNAr powers the engine of drug discovery and production, but electronic demands restrict access to important chemical space. We describe an e-SNAr strategy to bridge this gap that operates under air at RT with catalytic charge, simplifying scalability. https://t.co/Sk8uDTyN7x
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@reggiemills28
Reggie Mills
25 days
Metal–aryls are crucial productive intermediates in cross-coupling, though for cobalt they have rarely been observed during catalysis. Congrats to Kavita, Bhaswati on a landmark study of isolable, active cobalt–aryl catalysts for sulfone cross-coupling https://t.co/jS5uJ2gT9B
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@scrippsresearch
Scripps Research
2 months
Across two studies in @ScienceMagazine and @Nature, Phil Baran’s lab (@BaranLabReads) reveals a practical radical cross-coupling platform for constructing complex molecules using sulfonyl hydrazides—cleanly releasing nitrogen like a “rocket boost” for molecular complexity. With
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@JDerosaChem
Joseph Derosa
3 months
Fantastic visit at @UniofNottingham School of Chemistry today sharing some of our recent work in @derosalab using voltage control to enable selective electrosynthesis and catalysis. Thanks to @miriamoduill for the gracious hosting and organizing great discussions with faculty!
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@pchirik
Paul Chirik
4 months
Great work from @ChirikGroup’s Adam and POP as well as our collaborators @bmsnews @ChicagOChemO @stevewiz06, Heejun Lee and Eric Simmons.
@J_A_C_S
J. Am. Chem. Soc.
4 months
Phenoxyimine Iron Aryl and Alkoxide Complexes as Reactive Intermediates in Iron-Catalyzed C(sp2)–C(sp3) Suzuki-Miyaura Cross-Coupling | Journal of the American Chemical Society @PrincetonChem @Princeton @pchirik
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@JDerosaChem
Joseph Derosa
4 months
Bit late, but congrats to Zi, Ethan, and Bryan on an insightful study highlighting the impact of redox mediators on electroreductive Fe catalysis! We anticipate that this approach to access low-valent Fe will expand the electrocatalytic toolkit for organic synthesis. Stay tuned!
@derosalab
Derosa Lab
4 months
Congrats to Zi and team on the publication of our study on a redox mediator strategy to electroreductively harness Fe(I) in alkyne semi-hydrogenation! This work is now published in @ACSCatalysis - stay tuned for more from #TeamFe. #chemtwitter #newPI https://t.co/ovKaz3k28s
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@derosalab
Derosa Lab
4 months
Congrats to Zi and team on the publication of our study on a redox mediator strategy to electroreductively harness Fe(I) in alkyne semi-hydrogenation! This work is now published in @ACSCatalysis - stay tuned for more from #TeamFe. #chemtwitter #newPI https://t.co/ovKaz3k28s
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pubs.acs.org
The development of electroreductive Fe-catalyzed processes for organic synthesis has remained scarce compared to other earth-abundant metals despite inherent advantages such as cost, low-toxicity,...
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@EngleLab
Engle Lab
4 months
One week to go! 2025 OM Bootcamp @scrippsresearch kicks off on Aug 4th, 8 am PT. Welcoming participants in-person or over zoom, synchronous or asynchronous, low-spin or high-spin. Register👇 https://t.co/wXAQxOsan2
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@mx_million
Max Palkowitz
5 months
This is how you enable uptake of a new method! Hats off to the Knight Chemicals team for making a hydrazides coupling starter kit tailor made for medicinal chemists! Obviously I’m biased since I adore @BaranLabReads chemistry and the folks that develop it but dang what a product.
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@drdre4000
André K Isaacs
5 months
Calling all organic chemists! Come present in Worcester, MA! https://t.co/qiqOGONWAb
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acs.org
Call for Abstracts: Northeast Regional Meeting (NERM) 2025
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@marcuswdrover
Marcus Drover
5 months
**US-CAN Doctoral Excellence Award @WesternU -$160,000 to 25 PhD students for up to 4 years. - Must've had offer rescinded/cancelled from US school. -Expedited admission process. -Feel free to reach out, if interested in a PhD in inorganic chem! https://t.co/OejGUFExKE
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forbes.com
Western University, one of Canada’s leading public research universities, is launching an initiative aimed at luring away PhD students from premier U.S. institutions.
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@drughunter_com
drug hunter
5 months
Simplifying Synthesis with Radical Cross-Coupling | https://t.co/gX8xFaWYZj The recording of Phil Baran's (@BaranLabReads) Flash Talk, "Simplifying Synthesis with Radical Cross-Coupling" is now available on our YouTube Channel. Phil highlights how his group combines
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@derosalab
Derosa Lab
5 months
We are grateful to the @acsprf for funding our proposal on arene functionalization strategies for upconversion of aromatic feedstocks! Congrats to all the awardees this cycle:
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cen.acs.org
The spring 2025 grants total $8,630,000 in researcher investments
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@KLchemistry
Kevin Lam
6 months
We say: time to spiro! A fantastic work from Marylise Triacca in collaboration with @AstraZeneca: Out in Green Chem: #eSpiro – a metal-free, scalable electrosynthetic route to spiroketals via anodic oxidation. https://t.co/K1fk10AUeG #OrganoEchem #GreenChem #RealTimeChem
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@EngleLab
Engle Lab
6 months
atropisomers? positional isomers? both? We present beautiful and curious class of molecules today in @ChemRxiv. 🧐🪞 https://t.co/76QEU36cr3 @ASimlandy @0iTurki @pengliu_group
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@derosalab
Derosa Lab
6 months
SNAr powers the engine of drug discovery and production, but electronic demands restrict access to important chemical space. We describe an e-SNAr strategy to bridge this gap that operates under air at RT with catalytic charge, simplifying scalability. https://t.co/Sk8uDTyN7x
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@derosalab
Derosa Lab
6 months
Harnessing reduced Fe in electrocatalysis faces many challenges with respect over-reduction and catalyst instability. In this preprint, we describe a redox mediator strategy to tame a (P3P)Fe(I) species for semi-hydrogenation of alkynes as a model study: https://t.co/DPw0qpcxr2
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@JDerosaChem
Joseph Derosa
6 months
Standing on the shoulders of giants, we venture into reduced Fe electrocatalysis enabled by a redox mediator strategy. We are excited to use the lessons learned from this study to develop new forms of reductive Fe electrocatalysis! #chemtwitter #teamFe
@derosalab
Derosa Lab
6 months
Harnessing reduced Fe in electrocatalysis faces many challenges with respect over-reduction and catalyst instability. In this preprint, we describe a redox mediator strategy to tame a (P3P)Fe(I) species for semi-hydrogenation of alkynes as a model study: https://t.co/DPw0qpcxr2
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@OhmiyaLab
Ohmiya Lab
6 months
Just out on ChemRxiv! We report a carbonylative ring expansion of cyclic carboxylic acids via a spin-center shift mechanism. This strategy provides modular access to valuable sp³-rich cyclic scaffolds from readily available carboxylic acids. https://t.co/OG4DtJPDJw
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