Steve Wisniewski
@stevewiz06
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Process Chemist at Bristol-Myers Squibb by day. Springsteen fan by night.
New Jersey, USA
Joined January 2017
RT @pchirik: Great work from @ChirikGroup’s Adam and POP as well as our collaborators @bmsnews @ChicagOChemO @stevewiz06, Heejun Lee and Er….
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RT @ACSorganic: The 2025 Division of Organic Chemistry Executive Committee (minus a few members who joined via Zoom)
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We started working on this a few years and were able to go in and run it in our kilo lab. Watching the product crystallize was a great day showing we had the tools to develop base metal catalysis directly to our projects #BMSChemistry #ProudToBeBMS.
I see a pattern here. happy to share another story about advancing Base Metal Catalysis on scale! This time, a Ni-Borylation followed by a Pd-Suzuki coupling, Ni and Pd can definitely be friends 😊 Congrats to all the co-authors! #BMSChemistry
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RT @asymtmm: Just one more week to submit nominations for the 2025 Industrial Early and Mid-Career Investigator Awards, so nominate a colle….
organicdivision.org
The Early Career Investigator Award Symposium is for investigators who are in a non-academic setting and are no more than 10 years into their career.
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Our next step in developing nickel catalyzed borylations is to incorporate data science into our ways of working. Check out the latest from #BMSChemistry! #ProudtobeBMS
pubs.acs.org
Herein, we describe the optimization of reaction conditions for a nickel-catalyzed borylation using a combination of machine learning, high-throughput experimentation, and Bayesian optimization. A...
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Great to see the final version online! Awesome collaboration diving into catalyst activation pathways #BMSChemistry #ProudtobeBMS.
Happy to share the final version of our study on Pd bisphosphine mono-oxides complexes, appearing online this week in @J_A_C_S. Congrats to Shenghua and the entire team, and thanks to @DonnaBlackmond & #BMSChemistry for a wonderful collaboration! .
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Great day visiting the University of Houston to meet with faculty and students and chat about #BMSChemistry Thanks for the invite @reggiemills28 - looking forward to see your lab get started! #ProudtobeBMS
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One of our initial goals when we first wanted to develop base metals back in 2017 was to develop this kind of telescope. Awesome work by the whole team to see this become reality! #BMSChemistry #ProudToBeBMS
pubs.acs.org
The development of an efficient and general telescoped nickel-catalyzed Suzuki–Miyaura coupling (SMC) process from a nickel-catalyzed borylation reaction to form Csp2–Csp2 bonds without isolation of...
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RT @rebeccois: TCFH-NMI isn’t just for amide synthesis anymore! Check out this ketone synthesis from #BMSChemistry Greg Beutner and @Harvey….
pubs.acs.org
N,N,N′,N′-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) and N-methylimidazole (NMI) enable the facile and practical reaction of carboxylic acids with amines, alcohols, and thiols to form...
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Diving into some catalyst activation studies with the Engle and Blackmond groups! #BMSChemistry.
Is my bisphosphine ligand oxidizing? How is it happening? Does it matter? 🤔. If these questions keep you up at night 🛌, you're not alone!. Happy to share 3+ years of learnings, led by G4 student Shenghua together w/ @DonnaBlackmond #BMSChemistry.
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RT @ChicagOChemO: Congrats to my colleague Roger for this article on techniques for growing X-ray quality crystals!! Useful for new and ex….
journals.iucr.org
A catalog of techniques, tips, tricks, and encouragement for growing crystals suitable for X-ray crystallography.
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RT @rebeccois: Fun fact of the day: Suzuki reactions don’t have to be aqueous! Especially when it enables an efficient telescoped process!….
pubs.acs.org
The process optimization of a key step in the synthesis of NLRP3 (nucleotide-binding domain and leucine-rich repeat-containing protein 3) agonist BMS-986299 is reported. The step is a convergent...
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Check out the latest from #BMSChemistry! Congrats to the other authors!
pubs.acs.org
The development of a practical and scalable synthetic route to BMT-773752-02, a key starting material for repotrectinib, is described. The original sequence exhibited various limitations such as use...
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Today’s the day! Congrats to Keary on the Baekeland Award!.
Can't wait for this catalysis jam-session next week with a stellar lineup, put on by @AcsJersey: @stevewiz06 @diaogroupNYU @pengliu_group @MillerGroupYale
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Need to set some stereocenters? Check out the latest from #BMSChemistry on this Asymmetric Transfer Hydrogenation! Great work by Seung Wook and the rest of the team
pubs.acs.org
Here we present a novel strategy for the synthesis of enantiomerically enriched tetrahydronaphthalen-1-ols. The reaction proceeds via an alkylation (via hydrogen borrowing) and ammonium formate-med...
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Awesome work by Reggie to dive into this methodology and mechanistic study - elevating Ni catalysis to a new level! Great collaboration between @ChirikGroup and #BMSChemistry.
Activation of nickel(II) is often-ignored in nickel(I/III) cross-coupling. For (FI)nickel(II), we show that well defined organometallic steps form nickel(0), enabling catalyst “activation” that recovers catalysis when radical side-reactions go off-course.
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Starting in a few minutes in room 344!. Come for the talks, stay for the networking session! @ACSorganic.
Join us March 20th at 2PM in Room 340 for Biopharma 101: Transition to Industry (a collab with YCC + MEDI). Hear the work of early career professionals. A ticketed networking session will follow from 6:30-8:30 at Gordon Biersch Brewery Restaurant). Sign-up to secure your spot.
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RT @FloHetConf: The afternoon session begins with a lecture from Dr. David George from BMS! Thanks for the lecture and thanks to BMS for sp….
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