Wonderful meeting you, @Dr_ASingh ! It was fascinating to learn about your recent work on human immune organoids to decode B cell responses in healthy donors and patients with lymphoma. Truly inspiring research!

New in #ComputationalBiology from the September issue—Intrinsic Epigenetic State of Primary #Osteosarcoma Drives #Metastasis. https://t.co/vQHyzt6xap @Irtisha_Singh @YusteinLab @TAMUmedicine @TAMUEngineering @WinshipAtEmory

Check out recent work from @satijalab on Multiplexed single-cell characterization of alternative polyadenylation regulators, published in @CellCellPress

Really enjoyed a thorough dissection of factors influencing APA using Perturb-seq presented by @satijalab! This research highlights the key proteins that regulate tandem 3'UTR APA and IPA. A key revelation of this study is that an independent set of factors influence APA and IPA.

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

Excited to share our recent work on "Recharging Mitochondria", published in @NatureComms. This work introduces a unique concept of "atomic vacancies" in nanoparticles, to boost mitochondrial biogenesis and bioenergetics. #Mitochondria #AgeRelatedDisorders https://t.co/PCFBTC0M1O

when the authors write “significantly increased” without a statistical test

We (Biology, Statistics and Health Science Center of Texas A&M University)are hosting 6th Annual symposium on ‘Cancer: Basic Science to Bioinformatics’. Date: September, 29th Venue: Rudder Tower, 5th Floor, 501 Registration deadline: Sept 18th @TAMU_Biology @TAMUstats

Meet the leaders of @CPRITTexas Center for Excellence in Cancer Research (TREC) @TAMU Directors Ken Ramos and Robb Chapkin Project Leaders: @LabRaghavan @Irtisha_Singh @ChakrabortySLab @s8shogo Mission: linking gene-environment-lifestyle interactions in cancer #AggiesEndCancer

Danish Saleheen stunned the audience with his story of building the world's largest cohort of human knockouts in Pakistan, which is the world's 5th most populous country with highest level of consanguinity ever known. #ASHG22 #DRIFT22

If a reporter is driven by a promoter of a single-UTR gene, addition of an enhancer increases transcript production. If the reporter is driven by a multi-UTR gene promoter, the enhancer does not affect transcript production, but instead increases poly(A) site cleavage activity.

We are very excited to share our collaborative work with @Irtisha_Singh published in @ScienceAdvances on understanding the role of nanosilicates in inducing downstream endochondral differentiation. Big shout-out to @AnnaBrokesh @Lauren_M_Cross for leading https://t.co/tqAq8gzo2u

Congratulations dear @AKGaharwar of @TAMUEngineering for your induction to @aimbe Great honor!

A reviewer is born

Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing

Online Now: The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation

Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day next Friday (3/4). All talks will be live-streamed (no registration required) at https://t.co/vKIvFdsWzs

The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation - ScienceDirect

Bioinformatics twitter: NCBI SRA released v3.0.0 with improved fasterq-dump (unsorted fasta mode(!)). It has potential to improve the data download experience. https://t.co/UvKWaWTFfx

A comparison of experimental assays and analytical methods for genome-wide identification of active enhancers https://t.co/ro3SQ1XdVX