
IOTN Moonshot
@IOTNmoonshot
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Official X account of the NCI Immuno-Oncology Translational Network (IOTN).
Joined October 2018
The Immuno-Oncology Translational Network (IOTN) of @theNCI is a Cancer Moonshot Initiative to improve immunotherapy outcomes for both “hot” and “cold” cancers - and to prevent cancers before they occur. Read more at and
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RT @Cancer_Cell: Online Now: Myeloid cell networks govern re-establishment of original immune landscapes in recurrent ovarian cancer https:….
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RT @CellReports: Neuroimmune axis in gastrointestinal cancers: From mechanisms to therapeutic breakthrough
cell.com
Zhang et al. have comprehensively summarized how the neuroimmune axis regulates cancer progression through modulating the tumor microenvironment in gastrointestinal cancers. The authors highlight...
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RT @scisignal: This week’s new issue of #ScienceSignaling has arrived! A new study defines the regulation of a receptor that’s central to a….
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RT @CellCellPress: Now online! Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures ht….
cell.com
A 50-year multi-tissue proteomic atlas reveals transcriptome-proteome decoupling, proteostasis decline with amyloid accumulation, and asynchronous aging clocks, identifying circulating senoproteins...
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RT @jitcancer: New #JITC article: Therapeutic potential of T-cell receptor targeting the HLA-A*11:01-restricted KRASG12V neoantigen without….
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RT @NatureCancer: 🌟Another timely Review @NatureCancer, by G. Dotti and collaborators 👇.
nature.com
Nature Cancer - Dotti and colleagues review chimeric antigen receptor (CAR)-engineered cell-based cancer therapy and overview its transition for solid tumors from CAR T to CAR-engineered innate...
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RT @Cancer_Cell: The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeu….
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RT @SciImmunology: Scientists show that paired analysis of #CD69 mRNA and protein levels can help identify potent CD8 T cells with enhanced….
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RT @NCICAPIT: Don't wait-register now for the CAP-IT Virtual Annual Summit on July 24, 2025! .Open to the public with exciting talks on can….
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RT @sitcancer: Attend tomorrow's webinar on Predicting Patients' Response to Immunotherapy from Tumor Histopathology and Blood! This webina….
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RT @NatureRevCancer: Perspective 🚨.Orsolya Vincze @OVincze, Thomas Pradeu &Co discuss how cancer research can be advanced using comparative….
nature.com
Nature Reviews Cancer - Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular...
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RT @NatureCancer: 📢Another REVIEW now ONLINE @Naturecancer 'Advancing therapeutics in small-cell lung cancer'. ✒️By Anish Thomas, Chirayu M….
nature.com
Nature Cancer - Thomas and colleagues review the latest preclinical and clinical studies on small-cell lung cancer and outline future directions on therapeutic strategies highlighting a role for...
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RT @NatureCancer: 🚨Read this REVIEW published @NatureCancer !.'The tumor microenvironment’s role in the response to immune checkpoint block….
nature.com
Nature Cancer - Boussiotis and colleagues provide an overview of the features of the tumor microenvironment, with emphasis on myeloid cells and non-immune cells such as fibroblasts and endothelial...
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RT @NatureCancer: 📢New Article published @NatureCancer !. 'Innate immunity and the NF-κB pathway control prostate stem cell plasticity, rep….
nature.com
Nature Cancer - Blanpain and colleagues delineate lineage reprogramming following PTEN deletion in different prostate cancer-originating cells, demonstrating that in basal cells the NF-κB...
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RT @Cancer_Cell: Online Now: A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven gr….
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RT @NatureRevCancer: Our July issue is LIVE! 🌞🥵🏖️ . It features articles on:.- Targeted protein degradation for cancer therapy.- Advances….
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If you use Spearman (or Pearson) correlation p-values from standard software… there's a 99.9% chance they’re wrong. Drs. Han Yu and Alan Hutson @Amherst73 of @RoswellPark reveal why in "A robust Spearman correlation coefficient permutation test" , the top-cited article of the.
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RT @ImmunityCP: Online now: Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells https:….
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