Graham Coop
@Graham_Coop
Followers
20,478
Following
2,913
Media
1,881
Statuses
35,608
Popgen @UCDavis . @gcbias @ecoevo .social . Tweets, grammar, & spelling are my views only.He/him. #OA popgen book
Joined July 2012
Don't wanna be here?
Send us removal request.
Explore trending content on Musk Viewer
Drake
• 2101858 Tweets
Kendrick
• 1804834 Tweets
LISA TEAM REDBULL
• 517781 Tweets
Lando
• 483538 Tweets
#GranHermano
• 304800 Tweets
GW最終日
• 232984 Tweets
Furia
• 223612 Tweets
Stars
• 144213 Tweets
Mauro
• 114621 Tweets
The Heart Part 6
• 107213 Tweets
Drizzy
• 103952 Tweets
Kabir Is God
• 100874 Tweets
連休最終日
• 76609 Tweets
Panamá
• 74059 Tweets
Santiago
• 70788 Tweets
Mulino
• 63124 Tweets
#LaCasaDeLosFamososCol
• 48694 Tweets
FEDERICO
• 48104 Tweets
ゴールデンウィーク最終日
• 46039 Tweets
REJECT
• 45036 Tweets
Juliana
• 41703 Tweets
Tom Brady
• 35494 Tweets
Millie Bobby Brown
• 30516 Tweets
Whitney
• 29977 Tweets
Manzana
• 27327 Tweets
Del Moro
• 21161 Tweets
Larson
• 16525 Tweets
ゴムの日
• 13824 Tweets
Mother I Sober
• 12940 Tweets
Belichick
• 11262 Tweets
Rial
• 10090 Tweets
Pinned Tweet
Your ancestors lived all over the world, but relatively few of them were your genetic ancestors (does that matter?)
31
343
789
You and I are related to each other, but the question of how closely we are related has two very different answers. One genealogical, one genetic. 1/n
11
453
1K
New release (v1.1) of Population & Quantitative Genetics book. Fully open access (CC-by). All code for figures provided.
15
409
911
Insulting people who are doing the right thing and correcting or retracting a paper is a really bad look. We need to be accepting of errors, and be kind to our colleagues, to make it easier to admit when things have gone wrong.
7
114
877
Welcoming our baby daughter to the world. Mum and baby doing well, & our son is excited about his new sister.
76
3
825
I just took a DNA test turns out I'm 100% sure that they mislead many people into an overly typological view of human variation.
8
158
733
A new (3rd) release of the "Population and Quantitative Genetics" book. As usual, the book is completely open access as are all of the underlying source code, figures, illustrations.
13
342
652
First full release of population & quantitative genetics notes. Now with R code links for all the figures and attribution for images
10
258
626
6
55
601
A hundred years of artificial selection (red & blue indicating up & down selection respectively).
23
179
585
Thrilled to be the new director of the Center for Population Biology
@ucdavis
, a wonderful community researchers spanning the breadth of evolution & ecology!
28
24
570
4 y.o. has invented the morning game of "giant ground sloth" where we lie under his duvet quietly, pretending that we're in our burrows. He might be a genius!
16
21
551
Piece of population genetics history: postcard from Motoo Kimura to Lewontin asking for reprint of Hubby and Lewontin 1966. Thanks to Steven Orzack for permission to post this.
6
156
545
Here's a set of R shinys for teaching my population & quantitative genetics class. I'm posting the code here
10
150
515
Maybe the real GWAS was the coauthors we made along the way.
9
77
463
Just released version 1.0 of Open Access Population & Quantitative Genetics book on GitHub. Suggestions of how other places to deposit it?
18
195
454
Excited to see this preprint out "A geographic history of human genetic ancestry" by Michael Grundler, Jonathan Terhorst &
@gbradburd
5
145
440
Complete set of pdf slides from undergrad population genetic class (EVE102).
9
109
413
.
@molly_przew
and I wrote a review of
@kph3k
’s book, The Genetic Lottery: Why DNA matters for social equality, for
@journal_evo
: [pdf: ] 1/6
12
179
405
A new paper claiming a simple model of genetics fit a range of social traits. It’s interesting data, but it’s a massive reach to say the model fit reflects genetic effects, as there’s no control for environment here. 1/n
9
107
386
Used this graph from Donovan et al […] in my Evolution lecture on human variation yesterday (data from Rosenberg 2011 …). Found it useful for teaching so posting it here.
14
87
352
Have bleeding and bruised lip from being headbutt during a four-year-old's temper tantrum. How's everyone else's working from home going? Anyone discovered the theory of gravity yet?
21
10
339
Tired of prominent evolutionary biologists & population geneticists feeling the need to defend the founders of our field from historical analysis. Darwin doesn't need you to rescue him.
6
36
330
The All of Us paper is rightly being criticized for its UMAP figure, which suggests an overly discrete view of human variation—a problem that is compounded by colouring the plot with self-identified race and then omitting the “self-identified” from the title & legend. 1/n
11
97
328
I love tea. I love genetics. But we're a long way from using polygenic scores to understand differences among groups in tea drinking & other behaviours. [Preprint version]
14
129
308
No. Beauty isn't making scientists rethink evolution. It's great to see more public discussion of sexual selection, but can we stop w. the iconoclasm. Fisher's runaway theory is literally textbook stuff
5
72
305
If we're going back to early pandemic twitter, can we go back to the phase of everyone posting their bread pictures instead of all the amateur epidemiology?
18
15
302
We're all closely related to each other. A blog post on our vastly complicated, overlapping family trees.
15
170
282
If I'm descended from my grandparents why do I have cousins?
2
103
288
Congrats to
@vsbuffalo
on the publication of his paper estimating the genome-wide contribution of selection to temporal allele frequency change
3
80
287
A blog post by
@kitchensjn
and me on visualizations of the sharing of human genetic variation 1/n
9
104
282
I want to take a moment to talk about a Motte and Bailey tactic that often gets disingenuously used to frame and restrict conversations around human differences among groups. 1/n
14
77
271
I dont have a PhD from Harvard, but I'm going to say the skincare based on your DNA is BS.
21
50
272
Will be updating population genetics notes for a class this fall. Slowly working towards an open book on topic.
6
72
267
The use of the phrase “ancestry-specific variant” is increasing, particularly to describe rare Single-nucleotide variants (SNVs). But these alleles are not ancestry-specific. They have not yet been found elsewhere, but they will be. 1/n
10
75
266
Family-based GWAS have become the gold standard for assessing causal genetic effects. They’re often said to offer an unbiased estimate of the average causal effect (ATE) of an allele or PGS. Here, we (
@carl_veller
@molly_przew
) evaluate such statements.
1
7
99
261
Just cancelled a class for the fall quarter. The university is completely inflexible on its in-person requirement, even for small graduate reading group classes. I'm teaching another class already, and as a parent of young, unvaccinated children I don't want the additional risk.
13
19
254
Having a cry in my office, wondering how long I can wait till I go pick up our kids.
8
3
251
I listened to an interview with the CEO of this new polygenic score & IVF embryo selection company (Orchid Health). It was not reassuring. 1/
5
87
243
@pastramimachine
@kanderson
@CT_Bergstrom
@KjblackJohn
A number of your peers have reviewed your tweet. We are afraid we cannot publish this tweet at this time, and ask that you withdraw it from consideration. We can transfer the reviews to our sister journal, which will consider it for $$$.
2
36
246
Interesting,
@ucdavis
has just introduced preprints category on the faculty merits/promotion file system. Nice way of moving things forward.
5
77
243
Some thoughts on genetic ancestry groups and genetic similarity
14
61
236
Sad to hear about Luca Cavalli-Sforza. What an amazing life
4
127
228
As a geneticist feel quite sad that Warren gave into demands to do this. I think it sets a very worrying precedence for people to expect genetic demonstrations regarding questions of identity (when they are not the same thing).
10
51
228
A really daft paragraph. Imagine society discriminates against (say) short people. Then as height has a genetic basis, so will discrimination, and so discrimination will built into PGS of traits affected by discrimination.
9
50
221
Gil Mcvean on the interpretation of PCA applied to population genetics data
4
60
220
Crept into 4 y.o. son's bedroom last night to drop off his water bottle. Stared in wonder at how small he seemed in the dark, pondered the fragility of children. Then realized I was looking at his teddy bear propped on his pillow, while and he was asleep under his covers.
7
0
215
.
@molly_przew
and I reviewed Harden’s book “The Genetic Lottery” earlier this year:
@kph3k
has provided a reply, to which we responded. See here for the exchange:
&
[to appear shortly]
6
65
210
The genetic ancestry labels that the NIH “All of Us” biobank genetic data returns seem likely to add to general confusion about genetics and race/ethnicity [see appendix A here: ] 1/n
3
75
210
Update to undergrad popgen notes. Quantitative genetics and response to selection pgs 87-113
2
53
209
I like tea & genetics, but will genetics tell us why tea consumption differs among countries? Some thoughts on polygenic scores & phenotypic differences among populations
7
107
199
We have posted a final notice about our failure to replicate the findings of our 2017 polygenic selection
@biorxivpreprint
.
@JeremyJBerg
@Xinjun90
4
49
203
The one good thing about this whole debate is that it again squashes the idea that geneticists are covering up some secret truth. Honestly we cannot agree on anything, other than the fact that racists are arseholes.
2
35
191
6 y.o insisted on taking a picture of me on his first day of first grade. Turned out surprisingly well
9
1
193
New preprint by
@carl_veller
and myself on the interpretation of population and family-based genome-wide association studies in the presence of confounding
3
67
190
One of the many issues raised here is that an ancestors this far back have an appreciable prob. of not transmitting any genetic material to you (eg 8 generations back ~13% prob), but they're still very much your ancestor. We shouldn't equate genetics with genealogy.
5
52
192
Head of the department told me that they awarded salary increases based on who'd got nature/science papers that year. I told him that I thought that was a terrible system. I didn't get the job.
What was your worst experience while on a job interview?
1K
60
498
3
6
190
Matt Osmond's preprint on estimating dispersal rates and locating genetic ancestors with genome-wide genealogies
5
81
183
Re. Elizabeth Warren. A plot of the probability of inheriting exactly 5 blocks of your genome from a specific ancestor (as a function of # generations back to that ancestor). Details here:
4
63
179
Interested in doing a postdoc in the Coop lab? Feel free to DM or email gmcoop @ ucdavis edu. This would be funded off my NIH MIRA so I'm excited to talk broadly about ideas and systems across popgen, evolgen, and statgen. Please RT.
6
233
180
Over the moon about this. The collaborations I have with folks in the lab is definitely the highpoint of my career, & so this award means a huge amount to me
Excited for
@Graham_Coop
's efforts being recognized with the
@ucdavis
Distinguished Postdoctoral Mentoring Award. SO deserving.
0
7
72
8
9
179
If you've found my open-access population genetics book useful, please consider donating to
@ucdavis
Ecology and Evolution undergrad summer research program. Every small donation helps!
4
65
177
I'm excited to see the impressive new height GWAS out. But I'm concerned with the continuing pattern of a big chunk of the sample size coming from 23&me. with the 23&me data not being included in the summary data released. 1/n
3
35
177
The UC Davis Center for Population Biology postdoctoral fellowship is now being advertised. This is a great opportunity to come join our wonderful community of Evolution & Ecology here at Davis.
Please RT
2
201
173
.
@vsbuffalo
preprint on the shortfall in genetic diversity in large populations (Lewontin's Paradox). "Why do species get a thin slice of π?"
3
62
177
2020 really just keeps on getting worse and worse, but the sheer delight of our 10-month-old squealing with delight as she learns to walk is bringing a lot of joy.
2
2
177
Our 2-month-old just got her first round of vaccines. Feels like a big weight lifted off us. Vaccinate your kids.
4
3
173
A reminder that eugenics in California alone led to the forced sterilization of tens of thousands of people, disproportionality targeting Hispanic people.
2
78
167
Human genetics should move away from using genetic ancestry group labels as sample descriptors (e.g. "European ancestry"), and towards using more readily interpretable statements about genetic similarity (and relatedness) 1/n
Some thoughts on genetic ancestry groups and genetic similarity
14
61
236
2
61
171
Just want to say how much I enjoy the machine learning in popgen work of
@SamurSciCop
&
@pastramimachine
(along with others like
@sarakmathieson
). Honestly, it took me a while to catch on to how important & powerful this work was. But it's completely changing field.
3
24
169
Much of past 2 decades has been spent moving away from simply declaring neutral theory dead, to actually quantifying the contribution of drift & linked selection to patterns of variation. Feel like this perspective is somewhat missing from recent twitter discussion of topic.
2
36
168
Ladies, if he:
Starts a conversation about the heritability of IQ on a dating app.
He's not your man, he's yet another evopsych prof desperately trying to launch themselves as an alt-right/IDW personality.
8
26
168
The endless set of press articles about the "extended synthesis" continues, yet they always seem to be a series of gripes about what are already well-established ideas presented at an intro level in many textbooks.
13
25
164
In honour of Mary Anning's birthday. One of my all-time favourite "Hark a vagrant" cartoons.
2
30
162
Congrats to
@vsbuffalo
on his preprint estimating the genome-wide contribution of selection to allele frequency change
2
51
165
Small children are quite capable of reaching their noses and yet choose not to blow them. Why? 1/n
5
29
165
I usually just delete the racist comments I get on my genetics & genealogy blog posts, but the one explaining at length how Eurasians evolved from an inbreeding event between an ALBINO pair of siblings followed by 1000 years of isolation was impressively unhinged.
6
7
162
Me seeing this video used to illustrate some aspect of academia for the 100th time today
@_Quazi_
@anorangeduck
(3/5) After a day of training, he can withstand significant perturbations (but sometimes you just get too many cubes in the face…):
17
99
553
4
19
160
As a British person in the states, I find it truly depressing that major US news sources are focused on the queen's funeral and not Puerto Rico.
8
11
158
Henry Joseph Coop was born on Aug. 26th. Henry & Susan are healthy & doing great. We're over the moon.
http://t.co/lMMIWHiuoQ
34
1
155
Teaching undergrad population & quantitative genetics this quarter, will be updating notes over the next ten weeks. First up HWE, relatives, and inbreeding. Draft relatively complete up to ~pg 26
3
39
155
While many of them are quite funny, I'd perhaps stop and think about junior coauthors before posting jokes about retractions. It's quite a stressful situation for them.
1
15
156
Matt Osmond has publicly posted his beautifully hand-animated talk on reconstructing spatial genealogies
12
55
156
The UC Davis Center for Population Biology postdoctoral fellowship is now being advertised. This is a great opportunity to come join our wonderful community of Evolution & Ecology here at Davis. Please RT.
1
173
155
You and I are related to each other. Genealogically we're closely related, cousins many times over just a few centuries into the past. But in any region of our genome we're only very distant genetic cousins. 9/n
6
12
150
JFC it's the holidays, I'm blocking anyone who responds to my post about genealogy with racist crap. Seriously get a f*cking life.
2
3
151
Well that's nice news for Friday, I just got my new green card.
6
1
151
Your recent ancestors lived all over the world
7
92
149
#Istudyevolution
using genomics & mathematical models to understand how humans spread across the world & adapted to the many environs they encountered
#DarwinDay2018
@sse_evolution
2
40
146
An argument with my 5 y.o. American son.
Him: A big tomayto
Me: No tomahto.
Him: No, tomayo!
Me: No, tomahto.
Him: NO! Daddy, tomayto! The big spinning thing that sucks up houses.
Me: Oh...tornado?
Him: Yeah tomayo
6
4
148
Congratulations to
@ErinCalfee
on the publication of her paper: Selection and hybridization shaped the rapid spread of African honey bee ancestry in the Americas
@PLOSGenetics
1
47
146
Allowing people & companies to upload data to genetic genealogy databases potentially allows attacks on the genetic privacy of many users
5
93
144