Alessandro Gozzi (@gozziale.bsky.social)
@Gozzi_Ale
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Senior scientist @IITalk 🧠 🐁 Neuroimaging, brain (dys)connectivity and autism @ERCGrantees
Rovereto, Italy
Joined July 2016
How do cortical perturbations affect fMRI connectivity? Not necessarily as one would expect! Our new work @NatureComms shows that cortical inactivation may unexpectedly INCREASE fMRI connectivity! 🧵below explains how. Spoiler: δ oscillations are key! 1/n
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RT @PsyPost: Scientists have uncovered how puberty reshapes brain connectivity in 22q11.2 deletion syndrome, a genetic condition linked to….
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RT @TaylorBolt8: First tweet on an exciting new manuscript online @NatureNeuro - in collab with @LucinaUddin and Catie Chang. We take a fre….
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RT @Kangjoo_Lee_: 🚀 I will be presenting about our 🧠 🧲 BrainCAP toolbox at #OHBM in two weeks! 🎉 I'm on the job ⚡ market this year for a t….
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RT @misicbata: Benchmarking methods for mapping functional connectivity in the brain | What is the best FC metric?….
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RT @cimec_unitrento: Study how local brain manipulations impact whole-brain connectivity. 🔬 1 Fully funded PhD at @cimec_unitrento, superv….
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RT @cimec_unitrento: 🧠 Use functional ultrasound imaging #fUSI to map brain networks mice - Fully funded PhD opportunity at @cimec_unitrent….
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RT @MeyerBaese: 🚨 #OHBM2025 attendees, the Keilholz MIND lab (specifically me, Lauren and @ShellaKeilholz ) are organizing a symposium! . C….
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RT @medical_xpress: #Puberty may alter #BrainConnectivity in chromosome 22q11.2 #DeletionSyndrome, increasing autism and schizophrenia risk….
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RT @GRabuffo: After a long journey, our paper is officially out in PNAS! 🚀 Huge thanks to the team — excited to finally share it with the w….
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Nice to see our preprint featured! .Thanks @callimcflurry and @_TheTransmitter for the excellent coverage!🐭🧠.👇 #neuroscience #autism.
An analysis of 20 autism mouse models point to two subtypes: One displaying out-of-sync brain activity and impaired synaptic pathways, the other with too much synchrony and dysregulated immune pathways. By @callimcflurry .
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Breathing isn’t just for life—it’s a brain pacemaker!.This excellent review reveals how each breath sends sensory waves that globally synchronize neural networks - with implications for "functional connectivity". Congrats to the authors!. 👉
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RT @AndrewZalesky: Outcomes for the first 60 MDD patients treated at our clinic @QLDNeurostimCen with robotically delivered & fMRI-personal….
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RT @ShihYYI: 1/ Six years in the making! Our preprint on SORDINO fMRI is out. We're sharing the raw data and sequence to facilitate brain-w….
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RT @Hiraselab_KU: Vittani, Lee, Wang, Hiraoka, et al. KI mouse expressing red fluorescent blood.In situ SpyTag/Catcher attachment of biose….
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RT @NTFabiano: There are two subtypes of autism: brain hypoconnectivity & hyperconnectivity. 🧵1/9
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Our latest work is online today @ScienceAdvances . ➡️Brain connectivity in carriers of high risk mutations for #autism and #schizophrenia U-turns across adolescence (hyper -> hypo). ➡️This switch is driven by synaptic remodeling. Full explainer below 👇.
➡️What's the significance of brain dysconnectivity in developmental disorders? .➡️And what are its underpinnings? .To address these questions we mapped connectivity in carriers of high-risk mutations for autism and schizophrenia➡️Here's what we found🧵.1/n
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RT @CarlosEAlvare17: Report: fMRI of 20 mouse models of autism (n=549 mice) clustered as hypo- & hyper-connectivity subtypes. In human auti….
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RT @Valerio_Zerbi: Proud of this work led by @Gozzi_Ale and Marco Pagani following 10y or r&d, massive multi-labs collaborations and lots,….
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I'd like to thank here all the collaborators involved in this 10-year effort, including lead authors @MarcoPagani1985 , @Valerio_Zerbi Adriana_Di_Martino & folks at @childmindinstitute @MilhamMichael plus @SFARIorg @ERC_Research for generous funding! Comments are welcome!.
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In summary, our results link phenotypic heterogeneity to biological variability in autism, highlighting synaptic & immune-realted syfunction as key drivers of brain dysconnectivity. Our findings also pave the way for a biologically grounded stratification of autism . 16/n.
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