📢PROGRxN-BCa, our #AI tool to predict NMIBC progression, is now out in @EUplatinum! Paper: https://t.co/qLjhdtGt32 Code: https://t.co/cYfZzvsZV7 App: https://t.co/63VkFcKzdP @UofTUrology @UofTSurgery @UofT_TCAIREM @CanUrolAssoc @BladderCancerUS @IBCN1997 @IBCG_BladderCA

Adjuvant RT reduces 2-yr locoregional recurrence to 8% vs 26% with observation (p=0.006) in locally advanced patients post-RC + chemo, with the strongest benefit in T3, T4, and N+ disease. Another piece adding to the discordance: as modern peri-operative NAT drives higher pCR

👏 Big congrats to @uroegg! New chair of urology at @UclaUrology

@kellygrant1 @globeandmail @LancetRH_Americ @UHN @UofTUrology @GSK_UofT @FleshnerNeil Link to post with full manuscript link: https://t.co/AvxgrsLHzX @ihpmeuoft @UofTSurgery

Gem/cis/durvalumab is approved in the EU for muscle invasive bladder cancer (NIAGARA study). It’s the only immune therapy study in the adjuvant or neoadjuvant setting with significant OS. ⬆️ pCR and EFS support this appr @OncoAlert @Annals_Oncology https://t.co/EfftVBphaF

@DavidDan_Ngn @GSK_UofT @UofTUrology @UofTSurgery @CanUrolAssoc Congrats @GSK_UofT and @DavidDan_Ngn!!! @UofTUrology

Looking forward to a great ride for a great cause!! @theRide2Conquer @RHamiltonUrol @thePMCF

PROGRxN-BCa, an #ArtificialIntelligence-based model to predict progression risk in #NMIBC and improve substratification of intermediate-risk disease: an international evaluation of 12659 patients. Presentation by @GSK_UofT @UofT. #EAU25 written coverage by @RKSayyid @USC >

This landed late in my inbox, but fantastic news from @ImmunityBio regarding their expanded access protocol for BCG! Hoping this moves forward smoothly - a much-needed win for our patients. #BladderCancer #BCGShortage @IBCG_BladderCA @BladderCancerUS @DrPatSoonShiong

We had the honor of meeting Dr. Girish Kulkarni, a leading expert in bladder cancer (@GSK_UofT), for an insightful discussion on BCG failure and trimodal therapy (TMT).

Enjoyed learning about the excellent AI work done by: - @liaojoe1 (CystoNet) - Dr. David Berman (AI-enabled tumour grading) - @VigneshPackiam @SWilliams_MD @ylotan @anirrjoshi @valarlabs (VESTA) ...and many more!

Thank you @IBCN1997 @LDyrskjot @mouwlab for inviting me to talk about #AI in bladder cancer at #IBCN24! Honoured to share the stage with @liaojoe1 @AndreaNecchi! Enjoyed learning from thought leaders around the 🌎! Proud to represent @UofTUrology @UofTSurgery @UofT_TCAIREM !

Great podium by @wettsteinms using @ICESOntario administrative data to suggest retrograde tumor cell seeding in urothelial CA. Decompression of upper tract ideally with nephrostomy (over stent) in patients with bladder CA. @GSK_UofT @UofT #CUA24

This work would not have been possible without the mentorship of @GSK_UofT @alistairewj, and support from CBCIS @UofTUrology @UofT_TCAIREM @CanUrolAssoc and @BladderCancerCA. Special thanks to all our 🇨🇦 collaborators @WesKassouf, @pcvblack, @RodBreau and many others not on X!

JUST IN: Durvalumab extends EFS and OS In muscle-invasive bladder cancer —major news with IO moving earlier stages in balder cancer ! @OncoAlert @OncologyTimes @OncBrothers @tompowles1 @TargetedOnc @OncLive https://t.co/YohdHPLptX

#ride2conquer starting now. Go Team ProActives! Thanks to all for the generous donations. See you at the finish. Riding with @GSK_UofT. @thePMCF @UofTUrology

Final results of #CORE001 trial out now @NatureMedicine (1/14) 35 pts with BCG-UR CIS treated w/ Creto + pembro 👉12mo CR (per RBB) = 57.1% (ITT) 👉24mo CR = 54% *(Auth Corr) 👉No patient progressed to MIBC 👉No synergistic toxicity @garysteinbergmd https://t.co/zo8VHxmYol

A serious question for adjuvant papillary only trials is what the role.of turbt is vs the therapy. This is why especially for papillary disease the future is neoadjuvant (ie ablative) or randomized.

KN057 - papillary only BCGu #bladdercancer cohort. 12 mo DFS =43.5%, median DFS = 7.7 mo, 14% grade 3+ AEs. In ballpark of other drugs (standard caveats apply): 803 = 55% Nado = 44% Atezo = 49% (18 mo) Congrats @AndreaNecchi @GSK_UofT @Merck https://t.co/3CfTj03JFW

Spread the word - details finalized for a Sunday, post-dinner gathering at #CUA24 @CanUrolAssoc. Band will hit the stage at 930pm. All funds to @PROCUREqc Space is limited at the venue so don’t delay. Hope to see you there!