Scott Eggener
@uroegg
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Truth and science matter. Support both.
Professor of Surgery and Radiology (Urologic Oncology), University of Chicago
Joined February 2013
Yet another thought-provoking piece by Dr Welch . Would be great to see contemporary RCT's in this space (challenges galore). Routine Surveillance for Cancer Metastases — Does It Help or Harm Patients? | New England Journal of Medicine
nejm.org
Research generally suggests that routine surveillance after cancer treatment finds more recurrences — leading to more surgery, chemotherapy, and radiation — without affecting the risk of death.
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Wide variety of opinions, specialties, patient perspectives, policy makers contributing discussion to a public health conundrum: save lives from PrCa while minimizing overDxRx.
academic.oup.com
Abstract. Prostate cancer (PC) is a major cause of cancer-related deaths worldwide, with far more diagnoses than deaths annually. Recent discussions have c
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'Cancer' labeling: article largely about DCIS, but endless analogies to Gleason 6/Grade Group 1 prostate cancer . Hopefully, tides are a turning.
nytimes.com
Some oncologists suggest that, for certain early cancers not at risk of spreading, the term “cancer” should be avoided.
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Experts Are Debating Whether Some Cancers Shouldn’t Be Called That.
jamanetwork.com
This Medical News article discusses the ongoing debate about whether the word cancer should be dropped from the names of indolent tumors of the prostate and breast.
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We asked three big-brained superstars to share thoughts on a very important topic. My $0.02: "potentially clinically significant" far more accurate than "clinically significant".
auajournals.org
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Powerful data, we can/should do better . Similar/better benefit than many extraordinarily expensive drugs . Right up alley of @RichMatulewicz, Andrea King UofC.
jamanetwork.com
This cohort study evaluates the survival outcomes of currently smoking patients with cancer who entered into a smoking cessation treatment program based on the time between diagnosis and program...
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World champ??. Ronald Weiss was known to perform 14 vasectomies in a day and was done by lunch via @WSJ.
wsj.com
In a career that spanned three decades, he performed the procedure nearly 60,000 times and helped make male birth control palatable to men.
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Déjà vu. both the excellent early results and the predictable blowback.
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G-Minor-ambitious, exciting, and a clinically relevant question: Kudos to MUSIC patients/investigators: Editorial by @oncostan and me: Plz discuss. @wandering_gu @DrSpratticus @peepeeDoctor @KBGinsburg @redunndant @hollenbeck1971.
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More data/modeling to inform the GG1/Gleason 6 relabeling debate. Projected Outcomes of Reduced-Biopsy Management of Grade Group 1 Prostate Cancer: Implications for Relabeling
academic.oup.com
AbstractBackground. Implications of relabeling Grade Group 1 prostate cancer as noncancer will depend on the recommended active surveillance strategy. Whet
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Powerful essay by co fellow and close friend Joe Pettus. Some new twist and insights into the age-old “when the doctor becomes patient”. When One Day Becomes Today
jamanetwork.com
After he learned that his congenital bicuspid aortic valve needed replacement, a urologic oncologist describes, in this narrative medicine essay, the pain and helplessness he felt while recovering...
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Data suggesting more people with PrCa (current or treated) should be getting timely organ transplants. Zero evidence (to my knowledge) immunosuppression alters natural history of PrCa. @twattskristof @AaronDahmen @wandering_gu .
bjui-journals.onlinelibrary.wiley.com
Objective To analyse the management and outcomes of individuals diagnosed with prostate cancer either before or after organ transplantation, as the impact of organ transplantation and associated...
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Whether you are an advocate of thoughtful PSA screening and treatment of localized disease OR argue vociferously against it, please digest this 30 year data (and remember it was largely palpable disease).
nejm.org
In this randomized trial, conducted between 1989 and 2022 to compare radical prostatectomy with watchful waiting, radical prostatectomy led to a 48% lower risk of death from prostate cancer and to ...
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Is there reliable randomized data in any solid organ cancer that a more extended LND improves survival??
nejm.org
Whether extended lymphadenectomy is associated with improved disease-free and overall survival, as compared with standard lymphadenectomy, among patients with localized muscle-invasive bladder canc...
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Summary of “CAncer or Not Cancer?: Evaluating and Reconsidering GG1 prostate cancer (CANCER-GG1?)” symposium with ~50 folks from @ancan501c3 , @ASPI_INTL, @PCFnews, @Movember, CDC/NCI, thyroid/breast cancer experts, and all sorts of PrCa disciplines.
academic.oup.com
Abstract. Prostate cancer (PC) is a major cause of cancer-related deaths worldwide, with far more diagnoses than deaths annually. Recent discussions have c
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RT @chadinabhan: You have to hear this "brilliant" idea from @CanesDavid who formed @WellPrept to "personalize" educating patients while re….
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A lot to unpack but intriguing; more work to be done. West African Genetic Ancestry, Neighborhood Deprivation, and Prostate Cancer
jamanetwork.com
This case-control study examines the interactions between West African genetic ancestry and neighborhood deprivation in association with modifying prostate cancer risk and mortality among Black and...
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Nonsensical Interstate Telehealth Laws are Perplexing and Frustrating. None other than @seanmmcbride is a plaintiff in an important lawsuit to potentially improve the landscape. State Medical Boards and Interstate Telemedicine in the Courtroom
jamanetwork.com
This Viewpoint examines physician licensure requirements administered by state medical boards and 2 lawsuits challenging the restrictions placed on interstate telemedicine.
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Potential game-changer, impressive long-term work by scientists and trialists. Will likely be approved soon and become common. Reminder: ain't perfect, don't assume 100% accuracy, know the sens/spec/PPV/NPV.
thelancet.com
Our results suggest that [89Zr]Zr-girentuximab PET–CT has a favourable safety profile and is a highly accurate, non-invasive imaging modality for the detection and characterisation of clear-cell...
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