Giacomo Calini
@GCalini
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Colorectal Surgeon/Assist.Prof. Surgery (RTDa) @UNIBO | #PhD student | #robotic #surgery | @REMINDERsurvey | #Research @MayoClinic | Curious | Husband/Dad
Italy
Joined May 2013
As #VisitingResearchFellow, I am deeply grateful for the support and the example of the greatest mentor @DrDavidLarson ! Truly #CRS @MayoClinicSurg is a extraordinary environment of brilliant and careful surgeons governed by practice, #education and #research
@MayoMrfa
Rising star @GCalini In #CRS from @MayoClinic @MayoClinicSurg teaching us about intracoporeal #Crohn’s #surgery western surgical
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Great! 🚽📱😩💩 Like we needed 1 more cause for hemorrhoids. 37% of smartphone users spending > 5 mins/visit on the toilet, compared to 7% of non-smartphone users (p=0.006). Smartphone use on the toilet associated with 46% ⬆️risk of hemorrhoids (p=0.044) https://t.co/LJFKzBx2Qe
journals.plos.org
Smartphones are ubiquitous in daily life, with many people now using them while sitting on the toilet. Despite anecdotal evidence that length of time spent on the toilet is a risk factor for hemorr...
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@Carste92 @alice_gori @ClaudioIsopi @DFerrariMD @DrEmanueleRausa @GianlucaPellino @AntoninoSpin #ColorectalSurgery #RectalCancer #TME #SurgicalOncology #NeoadjuvantTherapy #NAT #EvidenceBasedMedicine #CollaborativeResearch #SoMe #SoMe4Surgery #SurgEd #Education #SurgicalResearch #AnswerYourQuestions
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Thanks to the COVID-CRC Collaborative Group 🇮🇹and to the authors @ MatteoRottoli @Carste92 @alice_gori @ClaudioIsopi @DFerrariMD @DrEmanueleRausa @GianlucaPellino @AntoninoSpin and all the authors
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What should change: - No RCT explored pCR and surgical outcomes with a timing >12 weeks! An exception (almost) is the ongoing RCT TiMiSNAR comparing 8w and 12w (min) https://t.co/4kOzn4ugWR
@IgorMonsellato Our TIMING study justify the equipoise of a >12w timeframe after SCRT !!
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What was new: - >12 w between SCRT and surgery showed significantly improved pCR rates (OR 4.99 !!!) with similar surgical outcomes.
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We found out that: - Delaying surgery (>12weeks) did not increase surgical complications after NAT differing from the recently published CRONOS Study (10.1001/jamasurg.2023.2521) - An optimal time to surgery after nCRT was not associated with pCR or any surgical outcomes.
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We compared time from Neoadjuvant therapy (NAT) to surgery stratified for - timing (<8w; 8-12w; >12w) - different NAT protocols: Chemoradiotherapy (nCRT), Short-course radiotherapy only (SCRT) Long-course radiotherapy only (LCRT) and Total Neoadjuvant Therapy (TNT)
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This new study explores the optimal timing of rectal cancer resection after neoadjuvant therapy (NAT) to maximize oncological benefits while minimizing perioperative risks. Data comes from the largest national cohort for colorectal cancer in Italy (81 centers; >18000 pts).
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🚨🚨🚨 New study alert "Rectal cancer surgery TIMING after neoadjuvant therapy: balancing downstaging and perioperative outcomes" just published in Surgical Oncology https://t.co/uBlKzgxJqC
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To my friends and amazing research fellows. Thank you for sharing your brilliant minds with me. I am grateful and proud of all your accomplishments @escp_tweets #tripartite @MayoClinic
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⏳ Have you filled out the GRIFF Collaborative survey yet? We’re building global consensus on intestinal failure & fistula care—and your input is key. 📝 It only takes 4 minutes: https://t.co/3RPHYaO4iu 🔁 RT to help us reach more voices! #GRIFFcollab #ECF #MedTwitter
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#INTESTINE study results are out https://t.co/RKrOtPk4BX
academic.oup.com
This trainee-led, international, multicentre, retrospective study includes patients with Crohn’s disease performing a temporary stoma during surgery. The s
🚨 New data on #temporarystomas in #Crohnsdisease: 🔹 Reversal @ 6mo: 30.2% 🔹 Reversal @ 18mo: 56.9% 🔹 Non-reversal: med therapy (39%), unfit (17%), patient's choice (20%) 🔹 Stoma morbidity: 29.4% "Temporary" often isn’t. #IBDsurgery @BjsOpen @GCalini @ZGaroufalia @SWexner
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🚨 New data on #temporarystomas in #Crohnsdisease: 🔹 Reversal @ 6mo: 30.2% 🔹 Reversal @ 18mo: 56.9% 🔹 Non-reversal: med therapy (39%), unfit (17%), patient's choice (20%) 🔹 Stoma morbidity: 29.4% "Temporary" often isn’t. #IBDsurgery @BjsOpen @GCalini @ZGaroufalia @SWexner
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Exciting news! Our article on abdominal drains in emergency colorectal surgery received enough views to be a Top Viewed Article. Read it here https://t.co/hPaTTmGWN1
#TopViewedArticle @wileyinresearch @ColorectalDis @YouESCP @escp
onlinelibrary.wiley.com
Aim Intraperitoneal drains are often placed during emergency colorectal surgery. However, there is a lack of evidence supporting their use. This study aimed to describe the efficacy and safety of...
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Do you agree or not? @ASCRS_1 @ACPGBI @SAGES_Updates LASER Focus on Long-Term Outcomes for Diverticular Disease
jamanetwork.com
Surgical management of diverticular disease is individualized and rooted in shared decision-making between patients and surgeons.1 High-level data from clinical trials are critical to enable data-d...
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Here we go again!? #diverticulitis #rct Sigmoid Resection vs Conservative Treatment After Diverticulitis
jamanetwork.com
This prespecified 4-year analysis of the LASER randomized clinical trial compares quality-of-life, complication, and recurrence outcomes of surgery vs conservative treatment in patients with recurr...
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Interesting new Finnish RCT in @JAMASurgery evaluating ICG's impact on anastomotic leak in colon surgery. The results won't make you switch camps, regardless of which one you're in, but they're important: -No difference in AL rates, reoperations, or overall complications between
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Congrats to @JyiChengNg (a rising resident in GS at Hopkins!) for helping to define a significant improvement to prognostics in #Rectal #Cancer. https://t.co/GNvaJUvBN2
@MayoClinic @MayoCancerCare
academic.oup.com
In rectal cancer management, clinical staging (cTNM) has historically been used to predict prognosis. However, recent evidence suggests that pathological s
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Just out https://t.co/TTXTNZ6VCi Endoscopic Recurrence Reduced after Extended Mesenteric Resection Multicentre, Randomised Control Trial (6, 12 and 18 months post true Extended Mesenteric Resection) @AGA_Gastro @NatRevGastroHep @NEJM @NatureMedicine @LancetGastroHep
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