Francesco Maura
@FrancescoMaura4
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Assistant Member, @MSKCancerCenter , @MSK_DeptOfMed, #NYC, myeloma, #mmsm, genomics, #WGS, #haematology
Manhattan, NY
Joined August 2019
RT @DrKTakahashi: 🚨 New paper in @NatureGenet !.How does cancer chemotherapy reshape the HSC landscape and drive the evolution of therapy-r….
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RT @CancerGrand: Important new research from one of our Cancer Grand Challenge’s teams could help to improve cancer treatment choices in th….
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RT @BloodPortfolio: Today, patients with multiple myeloma, and those with precursor conditions, are prognosticated by measuring tumor burde….
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The lab and the myeloma team at @MSKCancerCenter are very excited to welcome my friend and long term collaborator @BachisioZic and to host the rising star @hollyleeYJ for the rest of 2025 as visiting scientist @szusmani #mmsm
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It was fun to work with @RossFirestone in writing this editorial for @BloodPortfolio #Blood "More than myeloma: the trouble with “normal” plasma cells", on the recent article from @nickbolli @matteoclaudio84 @MSKCancerCenter @MSK_DeptOfMed #mmsm.
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RT @GreenLymphoLab: Lymphoma Microenvironment Archetype Profiles (LymphoMAPs). Just presented by @dgermain21 at #18icml @icmlugano, now ava….
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RT @TimourBaslan: 3 postdoctoral positions (1 comp, 2 experimental) available @ BaslanLab/Penn. We employ computation & functional biology….
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RT @oncodaily: Biallelic Antigen Escape is a Mechanism of Resistance to Anti-CD38 Antibodies in MM - @FrancescoMaura4 . @BloodPortfolio @Be….
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RT @BrunoPaiva_UNAV: #EHA2025 CTC session in myeloma and amyloidosis #mmsm .CTCs are fighting for a sit on the table of routine staging of….
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Our lab fantastic postdoc @juanjogrcs will present today our study on CTC in multiple myeloma @mmsm. Several relevant findings by linking WGS, RNAseq and CTC. Great collaboration with @TomasJelinekMD @BenDiamondMD @szusmani @MSKCancerCenter @OsuChsd @univmiami @theMMRF #mmsm.
Almost ready to present our work about #CTCs at #EHA2025, come to learn about how #liquidbiopsies can change the paradigm of #mmsm!
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RT @Myeloma_Doc: #Myeloma Paper of the Day: Biallelic antigen escape may be mechanism of resistance to anti-CD38 antibodies; L153H & C275Y….
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Huge thanks to our amazing collaborators @MayoMyeloma @Rfonsi1 @NBahlis @myelomaMD @RaabMarc #NielsWeinhold for supporting this study and enabling so many great and ongoing collaborations! #mmsm 🙏🙏🙏.
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This study was was led by my incredible collaborator and friend @BenDiamondMD who work very close with @lbaughn #AlexandraPoos #MansourPoorebrahim to characterize and functionally validated these events. Thanks also to @SanofiMyeloma for their help with CD38 3D protein modeling.
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here the X/Twittorial we released few months ago, summarizing in more details the key findings:
Just before the holidays, new preprint from the lab on @biorxivpreprint! Super talented @BenDiamondMD reports CD38 loss as mechanisms of resistance to anti-CD38 MoAb in myeloma #mmsm Great collaboration with @HDMyeloma @MayoClinic @univmiami @UCalgary @SanofiMyeloma 👇👇🧵 1/13
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Interestingly, these events are observed later in time, often after the second exposure to anti-CD38 monoclonal antibody.
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Key findings: CD38 loss after anti-CD38 monoclonal antibody occurs more often than expected (10–20%). We also found mutations that keep CD38 expression intact but block anti-CD38 binding. #msmm #Immunotherapy.
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Happy to share our new work out today on @BloodPortfolio #Blood where we report CD38 loss as recurrent mechanisms of resistance to anti-CD38 antibody in multiple myeloma. Great collaboration between @MSKCancerCenter @MSK_DeptOfMed @UCalgary @HDMyeloma @MayoClinic #mmsm #wgs.
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It was a great experience and honor to present during my 1st IMWG in my hometown Milan 🇮🇹 our new data on MGUS/SMM progression #mmsm #wgs.
We’re off to an amazing start with @FrancescoMaura4 walking us through the nuts and bolts of progression from MGUS to myeloma along with @VincentRK @mvmateos @IrenemGhobrial @thanosdimop. @IMFmyeloma #mmsm
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RT @VincentRK: Just out! New IMS/ IMWG Definition of High Risk Myeloma. @JCO_ASCO #ASCO25. @Myeloma_Society @IMFmyeloma @NikhilMunshiMD @m….
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