Aleksandra Filipovska
@FilipovskaLab
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RT @HAntonicka: Our story about FASTKD5 is now published at @NAR_Open. It was an amazing collaboration with @hauke_hillen and @Antonio4194….
academic.oup.com
Abstract. The first post-transcriptional step in mammalian mitochondrial gene expression, required for the synthesis of the 13 polypeptides encoded in mito
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RT @LabScorrano: This poster is a must have for labs working on #MCS! A guide through the work of so many outstanding labs (apologies if we….
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RT @cell_club: Dysfunctional mitochondria trap proteins in the intermembrane space | The EMBO Journal
www.embopress.org
imageimagePoorly energized mitochondria trap a subpopulation of mitochondrial precursor proteins in the intermembrane space. This article introduces ‘mitochondrial triage of precursor proteins’...
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It takes two to TANGO2!. TANGO2 binds the heat shock protein crystallin alpha B to prevent aggregation of the intermediate filament desmin and its loss models TANGO2-deficiency disorder. Many thanks to our team, collaborators and reviewers. #metabolism
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RT @RehlingLab: Silencing mitochondrial gene expression in living cells | Science Wonderful that our paper is out….
www.science.org
Mitochondria fulfill central functions in metabolism and energy supply. They express their own genome, which encodes key subunits of the oxidative phosphorylation system. However, central mechanisms...
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RT @TheRackhamLab: Ready to make breakthroughs in gene editing and mitochondrial biology in sunny Western Australia?.Join our vibrant team….
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RT @hauke_hillen: The peer-reviewed version of our paper on human tRNA 3' processing is now published in @NatureSMB. Many thanks to the rev….
www.embopress.org
imageimageThe human mitochondrial RNase Z complex is essential for the production of mitochondrial tRNAs. This study reveals its complete structural framework, detailing its role in tRNA maturation...
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New structural and functional analyses show that FASTKD4 supports non-canonical RNA processing and MT-ND3 mRNA stability. Thanks to all authors for their contributions and the reviewers for their kind advice!. #RNA.#mitochondria.#mtDNA
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RT @LazarouLab: Update! We outline AIVE, an AI method for volume EM data. We show the benefits of AIVE for reconstructing your FIB-SEM data….
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RT @CochemeLab: Mini reunion of team 'Mito Dysfunction' at @CellSymposia #CSMito2024! Wonderful to catch up with Aleks @FilipovskaLab from….
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RT @ANZSCDB: 📢Registrations are now open for the ANZSCDB NSW Meeting!. Scan the QR code to secure your ticket 🎟️👇
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RT @TheRackhamLab: Better CRISPR base editors!.More efficient nicking of the unedited DNA strand improves the ability to edit hard to reach….
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RT @LazarouLab: Our latest preprint! Some beautiful cell biology in this one. "Presynapses are mitophagy pit stops that prevent axon degen….
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RT @ZurynLab: Out today! We find that an epigenetic modification (6mA) to the mitochondrial genome (mtDNA) influences lifespan and the heri….
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RT @ANZSCDB: We are excited to announce the 12th ANZSCDB South Australia meeting taking place on October 16, 2024! Join us for insightful t….
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RT @mitopinionated: New paper from us on the in vivo role of the LRPPRC/SLIRP protein complex and its crucial role in mammalian mtDNA gene….
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RT @langer_lab: 🥳🚨Paper Alert🚨🥳.Excited to present our latest work on #Opa1 in this newly published paper @ScienceAdvances by @sahola6 and….
www.science.org
Inhibition of Opa1 processing in mice allows normal development but exacerbates mitochondrial cardiomyopathy.
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RT @HAntonicka: Check out our latest pre-print with @hauke_hillen and @VuckoviccAna, where we show that FASTKD5 joins RNase P and RNase Z i….
www.biorxiv.org
The regulation of mammalian mitochondrial gene expression is largely post-transcriptional and the first step in translating the 13 polypeptides encoded in mtDNA is endonucleolytic cleavage of the...
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RT @Trends_Endo_Met: You can read this article by @FilipovskaLab for free for the next 50 days at the following link: .
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