Ana Vučković
@VuckoviccAna
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PhD Student at Hillen lab (International Max Planck Research School for Molecular Biology, University of Göttingen) Mitochondria is the 🔋🏡 of the 📱
Göttingen
Joined September 2021
MicroRNA genes have evolved and expanded within the genomes of multicellular organisms for over 500 million years. Today, we know that there are more than a thousand genes for different microRNAs in humans, and that gene regulation by microRNA – discovered by this year’s
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I am excited to join @CaltechCCE @Caltech as an Assistant Professor this November! The Fianu Lab will be a welcoming space for anyone interested in gene activity and genome stability. https://t.co/k8yDZZwsCT We are looking for team members at all levels—please reach out!
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Check out our latest pre-print with @hauke_hillen and @VuckoviccAna, where we show that FASTKD5 joins RNase P and RNase Z in processing mitochondrial RNA. FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites
biorxiv.org
The regulation of mammalian mitochondrial gene expression is largely post-transcriptional and the first step in translating the 13 polypeptides encoded in mtDNA is endonucleolytic cleavage of the...
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Five days of excellent lectures, poster sessions, scientific discussions, and networking opportunities took place at the #EMBO Workshop on Molecular Biology of Mitochondrial Gene Maintenance and Expression 👉 https://t.co/qTBwAA5nlI
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We are happy to announce that this year's Horizons in Molecular Biology will be held in Göttingen from September 9th to 12th. Register for Horizons 2024 now through: https://t.co/UkajWjVPAH.
#Horizons2024 #MolecularBiology #ScienceConference
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Happy to share a new preprint, in which we describe the mechanism of human tRNA 3' processing. We show why the RNase Z ELAC2 acts as a monomer in the nucleus, but forms a multi-subunit complex in mitochondria. Plase see 🧵 by @BhattaArjun2p for details! https://t.co/cY5Dj66wkw
biorxiv.org
Eukaryotic transfer RNA (tRNA) precursors undergo sequential processing steps to become mature tRNAs. In humans, ELAC2 carries out 3’-end processing of both nucleus-encoded (nu-tRNAs) and mitochond...
Very happy and proud to share our preprint on biorxiv where we describe two distinct mechanisms of nuclear and mitochondrial transfer RNA 3’ maturation. Thread below.
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Excited to share our work showing how the Integrator complex terminates RNA polymerase II (Pol II) transcription i.e. removal of Pol II from the DNA template Published in @Nature
https://t.co/CH3rsQJeK8 Many thanks to my mentor Patrick Cramer @mpgpresident for unwavering support
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Online Now: Structure of the multi-subunit chloroplast RNA polymerase https://t.co/PxfRA1Dntc
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Happy to share the results of a great collaboration with Thomas Pfannschmidt (LU Hannover), led by the amazing @paulafprado and Frederik Ahrens. Together, we determined the structure of the multi-subunit plastid-encoded RNA polymerase from chloroplasts! https://t.co/3sBbq6pevn 🧵
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I have the honor and pleasure of co-organizing the EMBO workshop on Molecular Biology of Mitochondrial Gene Maintenance & Expression, with an amazing lineup of speakers! Join us in Poland from May 19-23! Early-carreer researchers especially encouraged! https://t.co/xmH3m5QXGC
meetings.embo.org
The mitochondrial genome is essential for cellular energy transduction and cell viability. Mitochondrial DNA (mtDNA) is replicated autonomously, and transcription and translation of mtDNA-encoded pro…
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This one was special! Very proud of our work, despite the long journey and dealing with most hostile reviews ever received. Major credit to @MiChAeL_900922, @franziska_f1nke, @AhmadRezaMehdi1, and @HummerLab
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The wait is finally over! 20th Horizons in Molecular Biology will take place from the 11th to the 14th of September, 2023 in Göttingen, Germany! Visit https://t.co/jWIcNrgGZP to register NOW!🥳
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