MRC MBU
@MRC_MBU
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Research at the MRC Mitochondrial Biology Unit is focussed on the involvement of mitochondria and their dysfunction in an ever-increasing range of human disease
Cambridge UK
Joined June 2014
Exciting study from @mkfrison92 in the Chinnery lab @MRC_MBU. Congratulations to all authors involved in the study! #mitochondria Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations | Science
science.org
Mitochondrial synthesis of adenosine triphosphate is essential for eukaryotic life but is dependent on the cooperation of two genomes: nuclear and mitochondrial DNA (mtDNA). mtDNA mutates ~15 times...
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Celebrating Postdoc Research โ National Postdoc Appreciation Week 2025! ๐ Sign up via the QR code to secure your place or visit https://t.co/wpF3Lk80mM
@Cambridge_Uni @MRC_MBU @TheCIMR #CambridgeUniversity #NationalPostdocAppreciationWeek #pintofscience #sciencecommunication
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Massive congratulations to @lucialugut on receiving the prestigious 2025 CSAR Award! ๐ Lucia's groundbreaking work in modeling and correcting mtDNA mutations paves the way for innovative future therapies for mitochondrial diseases. @MRC_MBU
https://t.co/De7DGu90Vj
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Congratulations to all Cambridge recipients of new @ERC_Research grants, including Corpus Fellow Dr Judy Hirst @MRC_MBU
Weโre thrilled to see six ERC Advanced Grants awarded to our talented researchers, supporting groundbreaking research in the biological sciences! Congratulations to all! Read more about the grants:
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Congratulations ๐
I'm honoured to be selected as one of the #Springboard25 grant recipients. Huge thanks to the Academy of Medical Sciences for their support!
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Huge congrats to @PavelNash29477 on publishing his PhD work! ๐ We showcase a safer mtDNA gene therapy using a novel mtZFN architecture compatible with a single AAV vector. Thanks to the entire team! @MRC_MBU @MBU_postdocs #MitochondrialDisease #mtDNA
https://t.co/go7NTMP9jx
link.springer.com
EMBO Molecular Medicine - Mutations in the mitochondrial genome (mtDNA) often lead to clinical pathologies. Mitochondrially-targeted zinc finger nucleases (mtZFNs) have been successful in reducing...
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Thrilled to share the last review of the lab led by @Tabara_LC and @MayukoSegawa on the mechanisms regulating mitochondrial morphology!!! @MRC_MBU Just out in @NatRevMCB. Thanks @lisa_heinke for the smooth editorial process!
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Call for abstracts ๐๐ทThe 18th UK Neuromuscular Translational Research Conference 2025 welcomes the submission of abstracts relating to neuromuscular diseases. Deadline 13th Jan 12 Noon Abstract submission instructions, event programme, and registration: https://t.co/DbwsKfmUST
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That was a great day! Thank you to our volunteers, our visitors and our hosts. ๐
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Beautiful #mitochondria art on display at #RAREfest today. Right beside our @MRC_MBU stand. @gavinmcstay2
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Big congratulations to @EloiseMLMrqs who won a poster prize at this year's @MRC_MBU annual symposium for her work in the lab over the last year ๐ฅณ @MBU_postdocs
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Great to catch up with Helena Cochemรฉ and Aleksandra Filipovska in Sitges #CSMito2024 ...both are doing great running their own labs - despite doing their PhDs in my lab...
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Dietary control of peripheral adipose storage capacity through membrane lipid remodelling
biorxiv.org
Complex genetic and dietary cues contribute to the development of obesity, but how these are integrated on a molecular level is incompletely understood. Here, we show that PPARฮณ supports hypertrophic...
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