Dennis van der Meer
@DvdM33r
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Postdoctoral research fellow @SFFNORMENT, applying imaging genetics techniques to big data to better understand brain development
Maastricht, Nederland
Joined October 2018
Thanks to an amazing set of co-authors, including @stinson_SE, @jarekrokicki, @jacob_bergstedt, @ISoenderby, @dsquintana, @SFFNORMENT, @ESTbiobank, @lehto_kelli, @MilaniLili, @oleaandreassen.
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New preprint! Strong genetic overlap between severe mental disorders and blood metabolic markers. Fascinating patterns: opposite effect directions of the markers on major depression versus bipolar disorder and schizophrenia. https://t.co/H0kCsWi0Wy.
#metabolicpsychiatry
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Understanding the Relationship Between Psychosis and Cardiometabolic Diseases - Postdoctoral researcher Dennis van der Meer and his colleagues are awarded 8 million NOK from the Research Council of Norway's FRIPRO program ... -
med.uio.no
Postdoctoral researcher Dennis van der Meer and his colleagues are awarded 8 million NOK from the Research Council of Norway’s FRIPRO program Research Project for Young Talents.
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Excited to share our new preprint. We reveal widespread genetic overlap across neurological and psychiatric disorders and a convergence of brain-related biological associations, contrasting their clinical distinction. https://t.co/9EMLW1FsUd
medrxiv.org
Neurological and psychiatric disorders are considered to reflect distinct underlying pathogenic entities. However, the extent to which they share genetic influences remains unclear. Here, we perfor...
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Excited (and relieved) to finally publish the preprint of a project we've been working on for a few years now: "The genetic architecture of human cerebellar morphology supports a key role for the cerebellum in recent human evolution and psychopathology". https://t.co/oWtDVR0LyH
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I am hiring! Come work with us in Oslo, Norway 🇳🇴, at @SFFNORMENT and Diakonhjemmet Hospital! We have a fully funded 3-year PhD position in #Neuroendocrinology focusing on the 🧠and #WomensHealth. Deadline March 1st. Please RT! https://t.co/3I7lmkNxWE
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Two open postdoc positions in our group! Interested in mental health in youth, risk/protective factors, and brain imaging? Attractive Norwegian benefits and work conditions, strong international network and interdisciplinary environment. @SFFNORMENT @Psykologiskinst 👇
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2) 3-4 yr postdoc linked to EU-funded @HEenvironMENTAL , large international network, big data, cutting-edge methods, work with @helga_ask @DvdM33r @oleaandreassen
https://t.co/XZOeGJaHwd
@EU_Commission
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New preprint🥳 An evolutionary timeline of the oxytocin signaling pathway https://t.co/HIGbiFff8k We show that ancient oxytocin pathway genes support cellular processes in humans. More recent genes sustain adaptive functions, bone preservation & are upregulated in the brain. 🧵⬇️
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Wrote a (I hope easily digestible) review paper on imaging genetics. Now online OA #TranslationalPsychiatry. Hope its of use! https://t.co/RypscIBBpS
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Happy to share our new paper in @molpsychiatry🥳! We found: 1) subcortical volumes share substantial SNPs with schizophrenia, 2) shared genes are enriched in neurodevelopmental processes, and 3) two genes are associated with thalamic volume in childhood. https://t.co/C8WLBgtg5h
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New preprint!! We found: 1) two schizophrenia gene sets with pre- versus postnatal cortical expression, 2) these sets associate with distinct neurodevelopmental processes, and 3) set-specific polygenic scores interact to predict diagnosis. Read more: https://t.co/vI5FM2drSV
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Insightful and well-written commentary @MeikeHettwer et al., and thanks for the kind words @sofievalk! Follow-up work underway... Always happy to discuss further, and see you at WCPG in September!
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Excited to share a new @biorxivpreprint comparing the genetic architecture🧬of the cortex🧠 with and without adjustment for global measures🌐(total surface area, mean thickness), extending some the work we did in our recent @ScienceMagazine paper https://t.co/2PJ0ni9LB5 1/n
Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness https://t.co/KMudxpTltK
#biorxiv_neursci
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ENIGMA's first in-person meeting in 3 years!! - ha, well it almost went to plan when we showed up with 47 people! Thank you Sophia Thomopoulos for organizing our first non-ZOOM @enigmabrains meeting in years @ #SOBP2022 !! + thanks to the restaurant(s!) for putting up with us
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Our latest multivariate GWAS now on BioRxiv! We studied 14 MRI-derived regional measures of adipose and muscle tissue from 39k individuals, finding large genetic overlap with cardiometabolic diseases, particularly for liver fat. https://t.co/OSJ3X7NEJG
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Now we are past the initial excitement, let's take a deeper look into this GIANT paper. A thread. https://t.co/X86v4zATbM
A remarkable moment in the history of GWAS! "... using GWAS data from 5.4 million individuals of diverse ancestries, that 12,111 independent SNPs that are significantly associated with height account for nearly all of the common SNP-based heritability." https://t.co/ps9eICDxEm
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Diphtheria And Tetanus Vaccination History Is Associated With Lower Odds of COVID-19 Hospitalization https://t.co/upfSab2Zyh now in @FrontImmunol 🦠 #COVID19 @uk_biobank
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Lots of laughs and insight gained by working on this review of neuroimaging studies of CNVs with an excellent team. Great, comprehensive figures!
A comprehensive review of neuroimaging studies of CNVs led by Claudia, @Sandra_98 @ClaraMoreau9 Borja @BogdanDraganski @ISoenderby and @JacquemontSeb
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