Jacob Bergstedt
@jacob_bergstedt
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Molecular epidemiology and causal inference. Psychiatric genomics. Postdoc at the Unit of Integrative Epidemiology, Karolinska Institutet, Stockholm.
Stockholm
Joined March 2018
Our @CoMorMent study identifying genetic, immunometabolic, lifestyle, and psychosocial factors underlying the link between depression and cardiovascular disease in @NatureCVR, with @JoellePasman @oleaandreassen @UnnurAValdimars @mcintosh2001 @cathrynlewis
https://t.co/iljTQfN2xP
nature.com
Nature Cardiovascular Research - Bergstedt et al. show that the effects of genetic liability to major depressive disorder can cause an increase in cardiovascular risk and that metabolic,...
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I am happy to announce that our paper “Quantifying the relative importance of genetics and environment on the comorbidity between mental and cardiometabolic disorders using 17 million Scandinavians” is out in @NatureComms! https://t.co/x0quxRc0yq 1/13
nature.com
Nature Communications - Mental disorders are often linked with cardiometabolic disorders, but the mechanism remains unclear. Here, the authors use comprehensive health data from Denmark and to shed...
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New pre-print from the @PGCgenetics #Depression Group: Multi-ancestry GWAS of depression with 685,000 cases identifies 697 independent associations, implicating known & novel drug targets. 🔗 https://t.co/eAh41d9XfA 1/n
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A study of 25,252 Swedish twins indicates that adverse childhood experiences associated with elevated risk of adult psychiatric disorders notwithstanding considerable familial (genetic & early environmental) confounding revealed through MZ/DZ comparisons.
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Amazing lead author Hilda Daníelsdóttir’s work assessing the link between adverse childhood experiences and risk of mental disorder diagnosis in adulthood using co-twin control analysis of 25 252 Swedish twins, just out in @JAMAPsych @UnnurAValdimars
jamanetwork.com
This cohort study investigates the association of adverse childhood experiences with adult psychiatric disorders after adjusting for familial confounding.
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(1/8) Our cohort profile of the Mental Health online Survey in more than 86,000 Estonian Biobank participants is now out in @IntJEpidemiol! 🎉🧬🧠 We are truly grateful to all participants and the EstBB team for making this study happen 🙏💙 Link: https://t.co/ksFMVg1tTl A thread
academic.oup.com
The Estonian Biobank is a data-rich national biobank that joins genomic, biomarker, electronic health records (EHRs), and questionnaire data to significant
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We are very honoured to see our study highlighted on the cover of @Nature ! Thanks to @darragh_duffy and our co-autors @BrunoCharbit @vrouilly @AnthonBertrand @MonsieurRoti @jacob_bergstedt
@Etienne_Patin @QuintanaMurci @LabExMI @institutpasteur for this great work !
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Our study on how smoking changes adaptive immunity with persistent effects is out in @Nature ! https://t.co/a4xIpfwcFZ Thanks to @darragh_duffy and our co-authors @BrunoCharbit @vrouilly @AnthonBertrand @MonsieurRoti @jacob_bergstedt @Etienne_Patin @QuintanaMurci @LabExMI !!!
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More interesting #humanImmunology work from @LabExMI cohort showing epigenetic dispersion and immune variation with age @jacob_bergstedt @darragh_duffy @QuintanaMurci et al @NatureComms
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Our #epigenetics study of how cell composition affects EWAS and how it, aging, CMV, and other factors shape blood DNA methylation signatures in the adult population, in @NatureComms. It’s been quite a journey, @Etienne_patin, @QuintanaMurci and @LabExMI.
nature.com
Nature Communications - Many studies assess epigenetic marks in white blood cells, but it is unclear how much immune factors affect the epigenome. Here, the authors show that fine-scale blood cell...
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Happy to share our latest study on the factors (intrinsic, genetic & environmental) driving DNA methylation variation in human blood. A great study led by @Etienne_Patin, @jacob_bergstedt and many others of the @LabExMI consortium.
nature.com
Nature Communications - Many studies assess epigenetic marks in white blood cells, but it is unclear how much immune factors affect the epigenome. Here, the authors show that fine-scale blood cell...
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@jacob_bergstedt presenting data from the @CoMorMent consortium on the relationship between cardiovascular disease & #depression
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Please RT. Post-doctoral position in single-cell genomics @institutpasteur (Paris) in the @QuintanaMurci lab, to work on the the genetic, epigenetic and evolutionary determinants of immunity-related traits. See:
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Elon Musk should buy 23andMe and release all GWAS summary statistics
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Our study with @g_hellenthal on detecting adaptive signals before and after European contact in #admixed Latin Americans is finally out in @MolBioEvol
https://t.co/MaMBgZutOa
academic.oup.com
Abstract. Throughout human evolutionary history, large-scale migrations have led to intermixing (i.e., admixture) between previously separated human groups
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Congratulations to Dr Cuadros Espinoza @5ebra2850 for the excellent PhD viva on adaptive admixture in humans (supervised by @Etienne_Patin). Thanks to the great jury @ras_nielsen @cschlebu @nbierne @G__Fischer & Cecile Berthouly!
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Please RT: Symposium "Genetic admixture: inference and evolutionary consequences" at the Collège de France @cdf1530, 30-31 May, Paris. Outstanding line up of speakers. IMPORTANT: attendance is free, and no registration needed. Will be in presence. See you in the sunny Paris!
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