Richard Phillips
@Dr_RPhillips
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Physician-Scientist at @UPenn. Brain Cancer Epigenetics. Tweets = mine.
Philadelphia, PA
Joined March 2019
Excited to share our new paper - We discovered the unexpected molecular target of MI-2, a promising glioma therapeutic. In glioma, MI-2 dramatically disrupts cholesterol metabolism by directly inhibiting lanosterol synthase!
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RT @PennNSG: New in @NatureMedicine, our researchers have found that a dual-target CAR T-cell therapy approach shows promise for slowing tu….
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New paper alert! In collaboration with the @adrianbracken and Brien labs in @MolecularCell we identify a specific PRC1 complex which is hijacked in #DMG to drive the malignant state. Lays the framework for a new therapeutic strategy! @PennNeurology @PennEpiInst @PennCancer.
Excited to share our new paper out today in @MolecularCell! We show that the H3K27M oncohistone rewires cPRC1, creating a unique dependency on CBX4/PCGF4-containing complexes, and also reveal a previously unknown function of CBX4. Highlights below (1/11).
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Amazing.
Just caught up with my PhD mentor, Susumu Tonegawa (1987 Nobel 🏅) in Janelia!. Fun fact: he was once an early investigator in Basel, Switzerland on a temporary contract. The contract ran out, his position was terminated, and . he just did not return the key 🗝️. He just went
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RT @LohiOlli: A new study in Nature challenges long-standing views on how Group 3/4 #medulloblastomas develop. Study group led by Prof. S.….
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Beautiful work, congrats @ophirshalem @GMBurslem.
Excited to to see our collaboration with @GMBurslem lab published today! This is part of our ongoing long term goal of achieving scalable non-disruptive and direct imaging and perturbation of the endogenous proteome.
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Congrats to newly minted Dr Dejauwne Young @EinsteinMed MD PhD candidate and future neurosurgeon scientist, on his thesis defence. Hugely impressed by your intellect and tenacity. Coming to a lucky neurosurgery residency soon, no doubt! @NdukaAmankulor @BrainRepairLab @bryandchoi
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RT @demishassabis: In the future soon, we will be able to communicate with many intelligent animal species - can't wait to better understan….
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Congrats @Dr_CJackson.
New for @ScienceMagazine, @Dr_CJackson led a study that elucidates specific myeloid-derived suppressor cells that may facilitate human glioblastoma progression and mediate tumor immunosuppression. ➡️
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RT @ItaiYanai: It seems easy to make fun of basic science – for example why would you want to study bacterial immune systems? But then you….
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Thrilled to be a named an @theNCI #CancerMoonshotScholar. All thanks to the team, mentors #FrancesJensen and our precious patients as we work toward better treatments for glioma @PennNeurology @PennCancer @PennEpiInst.
Today, the #BidenCancerMoonshot announced a new cohort of Cancer Moonshot Scholars and awarded $6 million to this next generation of innovators in cancer prevention, treatment, and diagnosis. Learn more about the Scholars:
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Truly visionary work. May end up being the most impactful technologies over the next few decades in biomedical science. Congrats to Dr Baker, @demishassabis and Dr Jumper!!!.
BREAKING NEWS.The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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RT @PennEpiInst: We are thrilled to announce the recipients of the 2025 Epigenetics Institute At-Large Pilot Grants! We look forward to see….
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RT @LilingWanLab: (1/n) excited to share that our study on how condensate-promoting ENL mutations drive tumorigenesis is out at @CD_AACR! h….
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RT @EricTopol: There's never been a disease-modifying drug for Parkinson's disease to slow its progression. Now there may be two emerging.….
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RT @sixers: 🩺@PennMedicine spotlight: . today we recognize Dr. Nduka Amankulor, a renowned brain surgeon and Director of the Penn Medicine….
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Congrats to team!.
Excited to share our early phase 1 results for bivalent #CARTcells in recurrent #glioblastoma. Now online @NatureMedicine. Awesome team effort! @PennMedicine @PennCancer @PennNSG @DrORourke2 .
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RT @francesarnold: We are thrilled to present a new #enzyme to the world, the first shown to break the man-made carbon-silicon bonds in #si….
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