🔮In vivo CAR-T has captivated big pharma. Here are 4 predictions on where this goes. 1️⃣Trials shift to kinetics + geography Not “B cells dropped,” but where, how deep, how long, what returns. 2️⃣Platforms > one-offs Proof = controllable delivery + re-dosing in 2 indications,

Tenured academia is really not "just a job." - can't be fired. - get a 5-month summer break. - complete flexibility on schedule/wfh - study what interests you -get paid more than enough to live comfortably. It's completely rational to work insanely hard to get this!

There's a new kind of biotech company in silicon valley, the 'human enhancement company'. I believe this is the next new category of technology company to yield not only a >$100B household name, but to truly uplevel human health and wellbeing. These companies are

Can AI cure disease & make science faster? @pdhsu @JorgeCondeBio and @eriktorenberg discuss (00:45) The Moonshot: Virtual Cells and Human Biology (02:58) Interdisciplinary Collaboration at Arc Institute (05:11) The Role of AI in Biology (10:18) Understanding Virtual Cells

What if we could manipulate biology as quickly and easily as we do software? That is the bet @pdhsu and @arcinstitute are making. Science is slow because biology is the most complex system we study and because we do not natively speak its language (DNA). Those constraints are

Delighted to share our Cancer Cell paper published today, co-authored by Dr. Alexander Biederstädt @ABiederstadt_MD and Dr. Rafet Basar @rftbsr9 reporting the first genome-wide CRISPR screen in primary cord blood NK and CAR NK cells. We identify key genetic checkpoints including

It's never meant to be personal so sorry to Vinay if it sounds this way, but this is beyond the best case scenario for biotech. Conservatives' clear message to FDA: be generous in allowing patient and family choice.

Hind, many congratulations on this important work & sincere thanks to the brilliant co-authors who made it possible. I’m so proud of all you’ve achieved and wish you every success as you begin your independent career. Excited to see what comes next!

RFK isn’t where he is right now because he’s right on every issue - it’s because he’s on the right side of the public’s anger towards the status quo. Now that he’s in, protesting change is going to get people and our industry nowhere. Better to be a part of the solution.

My take on RFK Jr is that while a disagree with many of his ideas and I think he has a questionable temperament, I do think he should be confirmed because in his case he was essentially part of the ticket and many Americans in part voted for him and for change in healthcare.

#Glioblastoma (GBM) is a devastating disease. But hope may be on the horizon. #CARTcelltherapy trailblazer @carlhjune shares how the revolutionary therapy has showed promise in recent trials involving #GBM patients.

Big news! 🥳🥂 In July 2025, I will be joining the faculty of University of Pennsylvania, @Penn_CBIO. The Goodman Lab for Synthetic Immunology will combine synthetic biology, genome engineering, and ML-driven functional genomics to study and manipulate primary immune cells. 🧵1/3

#Glioblastoma (GBM) is one of the most difficult cancers to treat, in part due to its immunosuppressive tumor microenvironment in which TGF-β protects the tumor. Research in @OUPAcademic’s Neuro-Oncology journal unveils a strategy to overcome this: https://t.co/RgnvGh5soN (1/3)

@CNS_Update #2024cns Understanding and Improving Quality in Neurosurgery symposium. Representing @PennNSG along with Dr. Zarina Ali. She’s a leader in #eras and #peripheralnerve surgery.

Biggest medical discoveries of the week (🧵) 1. The inflammation that can happen in severe COVID-19 can be prevented (in mice!) with an anti-fibrin antibody - named '5B8' ( https://t.co/sD3lsXdxs4)

Anthropic CEO Dario Amodei says AI could increase the rate of discovery in biology by 100x, compressing the total amount of progress that occurred in the 20th and 21st centuries to just a few years