Baayla DC Boon
@BaaylaB
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MD, PhD @MayoClinic |Neuropathology | Alzheimer's Disease | π©πΌββοΈπ©πΌβπ¬π©πΌβππ©πΌβπ«β₯οΈπ¬π₯π§ β₯οΈππΌββοΈππ§πΌββοΈππ»ββοΈππΌββοΈππΌ
Atlantic Beach, FL
Joined October 2019
π¨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimerβs shows superficial cortical AΞ² cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @DrNeuroChic
https://t.co/gAStfXlsTX...
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Agreed! What a great session, thanks to the great speakers and an interactive Q&A π
Honored to share a panel with this great line-up of speakers in such an insightful session discussing the underpinnings of clinical heterogeneity in AD #AAIC25 @AtypicalPIA @NSS_PIA @grinberg_t @KeirYong @BaaylaB @Rosaleena_M @hospitalclinic Thanks to the organizers! @ISTAART
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Interested to see how advanced microscopy holds the power to transform our understanding of therapeuticsπ¬π§ β¦come see our latest work. #AAIC25 Hall G session 2-3.30 pm integrative neuropathology in ADRD at 2.20 pm sharp @DrNeuroChic
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Tangle tau folks, check out this pre-print!!
Pre-print alert on #tangle maturity in #Alzheimers β
15 #tau antibodies β
human #hippocampus β
manual tangle maturity scale β
#pathomics approach to automate β
neuritic and tangle-bearing tau https://t.co/ml1cu3QzZt If you have not checked out @Google's @NotebookLM ,
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π’Call for collaboration! We're announcing a Clinically-Focused Work Group aiming to improve diagnosis & treatment strategies in #atypicalAD. Chaired by Drs. @DrVSPelak & Deepti Putcha! πJoin our kick off meeting on May 22, 10:05 AM CT:
alz.surveymonkey.com
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Beautiful neuropath work assessing regional distribution of AD pathology and neuroinflammation in PCA! Love the fine details on CAA and microglia circularity, fascinating findings on the parietal cortex - congrats Zeinab, Keir and team!
Pathology of posterior cortical atrophy vs amnestic AD- featuring detailed characterisation of regional amyloid, tau and neuroinflammatory response https://t.co/zQQQFaNArE Led by @Zedzeinab @UCLIoN, supported by @AlzSocResearch @BrainAppeal - some key findings:
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At #ADPD2025?? Go check today&tomorrow Sarah Basile at poster 174 on #amyloid-beta nitration and its role in fibrillation and #neuroinflammation in #Alzheimer. We would LOVE to hear your thoughts!
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[1/x] The journey to preventing brain diseases is long... filled with internal battles, road bumps, and uphill climbs (both waysπ). As I begin the daily check on our @NIHAging R01 grant status, I find that apparently brick walls are also now a part of the journey.
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Yaaaay! Today I got my first non-Dutch grant awarded by the Mayo Clinic ADRC for a two year project on β¦ π₯ amyloid plaquesπ₯³!
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Wooo, what a Monday. Just enough time to swing by the lab for a photoshoot before racing off to the airport. I try to take every chance I get to share how beautiful the brain is and how fun science isπ€©π¬π§
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Prepping for a school outreach event and reflecting on how awesome it is to have the opportunity to showcase some of your science heroes (and heroes who double as friends) in your Black History Month deck of influential scientists.
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Hasta luego @PuertoRicoPUR π΅π· I loved meeting your people and grateful to so many who shared their families' stories of loved ones lost to #AlzheimersDisease. ΒΏNecesitas ayuda? https://t.co/6IsP3e24gb
@sanbenito
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Neuropathology rocks!! Great keynote by @grinberg_t !
Big honor to give a keynote talk at the @HAIconference on ways neuropathology drives biomarker development in #Alzheimer. Grateful for the opportunity and the invitation! Looking forward to connecting with colleagues and the incredible discussions. @UCSFmac @alzassociation
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Day 1 of @HAIconference (HAI) is off to a moving start. With our experimental year outside of Miami, @DrMariaALZ leads us with a message of hope. As HAI is a #biomarker and #neuropathology community of hope translating into clinical application π
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So glad I finally made it to @HAIconference ! It was amazing to show our data, which would not be possible without the amazing collaborative infrastructure of the Mayo Clinic ADRC @NIHAging
Fantastic debut of @BaaylaB deep neuropathologic investigation of anti-amyloid treated brains. Masterful presentation and panel discussion π Great job co-chairing @relajoie π€ @HAIconference
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The only appropriate role of a health insurance corp is to pay bills, not to manage care. The only appropriate role of an employrer is to pay employees and taxes, not to manage care. The only appropriate decision-makers in health care are patients and their own doctors.
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π’ Please join @JeffAndTheBrain on January 30 for a Year in Review of the research in the field of #AtypicalAD! π Link to registration: https://t.co/vDnreDp7Ca
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π’ Dear @AtypicalPIA members, which publications of 2024 have been the most impactful in #AtypicalAD? Excited to announce that @JeffAndTheBrain will lead the @AtypicalPIA Year in Review on Jan 30! Save the date and share your opinion for the webinar here:
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Beautiful work by Liu et al. highlighting the importance of heterogeneity in amyloid-beta pathology, especially in the era of amyloid targeting therapies. I remember seeing this work at ADPD and am excited to see it published! @ElzHead @M_B_Miller
https://t.co/8qBvb4ZuMr
jamanetwork.com
This study investigates the binding properties of lecanemab in the brains of people with Down syndrome, in anticipation of their inclusion in clinical trials or access to antiamyloid immunotherapies.
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What a happy way to celebrate a Friday, @dennis_w_d and I welcomed the @GrinbergLabUCSF to Mayo for @CityofJax visit. Feels like a dream come true after such a long lasting friendship and collaborative history with @grinberg_t
@gowoon_son @flpsw @LiaraR_
@AbhijitSatpati
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