Daniel Burkhardt
@DBBurkhardt
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Digital Biology @ NVIDIA
Toronto
Joined January 2009
Ready, set, code! The Open Problems in Single-Cell Analysis competition at #NeurIPS2022 is open, featuring $25,000 in prizes & a new multimodal #singlecell timecourse deeply profiling hematopoiesis 🥳 🎉🧪🧫 Join us on Kaggle! https://t.co/XsiPyWrbrD To learn more, read on 🧵👇
kaggle.com
Predict how DNA, RNA & protein measurements co-vary in single cells
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🤯 Discover how you can scale transformer models to billions of parameters in PyTorch - without rewriting your pipeline. Dive into NVIDIA BioNeMo Recipes to see how FP8 acceleration, efficient sequence packing, and the Transformer Engine empower breakthrough R&D on NVIDIA GPUs.
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Today, we’re announcing Kosmos, our newest AI Scientist, available to use now. Users estimate Kosmos does 6 months of work in a single day. One run can read 1,500 papers and write 42,000 lines of code. At least 79% of its findings are reproducible. Kosmos has made 7 discoveries
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Edison Scientific is launching today, with our launch of Kosmos, the most powerful AI Scientist released yet. We are a spinout from FutureHouse, focused on building and commercializing AI agents for science. Try our newest agents, including Kosmos, on our platform today.
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What a PERFFect day to share our new preprint! With @tsion_abay #BobStickels @MerilTakizawa @ChaligneRonan and @Satpathology, we introduce PERFF-seq, a new experimental approach to studying rare cells with scRNA-seq via transcript-specific enrichment. https://t.co/woKvdEdOf0 1/n
biorxiv.org
Single-cell genomics technologies have accelerated our understanding of cell-state heterogeneity in diverse contexts. Although single-cell RNA sequencing (scRNA-seq) identifies many rare populations...
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Thrilled to announce the opening of the Srivatsan Lab ( https://t.co/mUPc2wHm0X) at the @fredhutch. The lab will be building new sequencing technologies to understand how our cells and bodies form over the course of development.
srivatsan-lab.com
Discovering, building, and communicating the wonders of biology to the world. We believe that our research can be a force for good in the world and that we have an obligation to conduct research...
The newest @FredHutch Basic Sciences lab opens its doors! The @SRsrivatsan Lab is developing new sequencing technologies to interrogate structure-function relationships during vertebrate development. The lab is growing and hiring at all levels:
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Thanks again @cellaritybio and @cziscience for making this possible! We’ve already got 100+ teams signed up. I can’t wait to see what the community comes up with 🤩
📣Competition Launch Alert! Open Problems – Single-Cell Perturbations, hosted by the non-profit collaboration - https://t.co/YZAI1yGosg 🎯 to predict how small molecules affect gene expression in various cell types. 💰 $100,000 Prize Pool ⏰ Entry Deadline: November 23, 2023
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📣Competition Launch Alert! Open Problems – Single-Cell Perturbations, hosted by the non-profit collaboration - https://t.co/YZAI1yGosg 🎯 to predict how small molecules affect gene expression in various cell types. 💰 $100,000 Prize Pool ⏰ Entry Deadline: November 23, 2023
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Thanks again to the incredible teams at @cellaritybio, @cziscience, and @kaggle for their support making this project a reality. Thanks also to the Core Team at https://t.co/upxA8GAS0r for their guidance and help planning!
openproblems.bio
Explore Open Problems in Single-Cell Analysis
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We're also thrilled to announce that we're splitting our prize pool 50/50 to include an all-new Judges Award 🧑⚖️ for best write-ups that help us advance our scientific understanding of the problem. You can find details on the Judges award here:
kaggle.com
Predict how small molecules change gene expression in different cell types
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For training, competitors have access to all perturbations in T cells and NK cells + 10% of the perturbations in B cells and myeloid cells. Competitors must then predict DE scores, -log(p-val), for the held out compounds in the held out cell types.
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For this year's competition, we are asking competitors to generalize experimental perturbations to unseen cell types. We test 144 compounds + controls (all from LINCS Connectivity Map) in PBMCs and measured scRNA at 24h. And we did this in 3 donors.
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I'm thrilled to share that our 2023 https://t.co/upxA8GAS0r competition is now live 🎉 More details in 🧵, and you can get started on @kaggle today to compete for $100k in prizes:
kaggle.com
Predict how small molecules change gene expression in different cell types
For our 3rd competition for #NeurIPS2023, we’re asking: can you predict a new algorithm for how cells respond to a drug treatment? Learning how #singlecells respond to perturbations will help support more efficient drug design. See more on Kaggle: https://t.co/8nttiznF6l
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I get DMs daily from people in tech who want to work on biology, so we built something: In August, we'll do a free, virtual course. Assumes no background in biotech, and you'll on-ramp into great projects, get intros to the best labs & companies, join an incredible network.
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We’re excited to launch #CZCellxGene Discover Census, a new capability that can cut parts of the #SingleCell analysis process from weeks to minutes. https://t.co/HJLtmvhryp
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Big News🚨: #CZCellxGene Discover Census launched today! https://t.co/GRjBDnKWS5 Built from >500 datasets, Census gives you efficient access to the largest aggregation of #SingleCell RNA data that’s immediately ready for analysis with harmonized labels for cell and gene metadata
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(1/n) Today I'm proud to present our work on learning dynamics in cancer using neural ODEs and optimal transport!
biorxiv.org
While single-cell technologies have allowed scientists to characterize cell states that emerge during cancer progression through temporal sampling, connecting these samples over time and inferring...
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Deep Science Ventures is launching a new PhD program, the Venture Science Doctorate, to put venture at the heart of research. It’s a 3-year, fully-funded PhD designed to provide solutions to key human and planetary challenges. Apply 👉
deepscienceventures.com
Reinventing the PhD, to put venture at the heart of research. Applications for the 2025 are now open!
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Which single-cell analysis tool is best? w quotes from @hoheyn @morris_lab @jzlevin @markrobinsonca @lucapinello @DBBurkhardt our @JulioSaezRod about LIANA https://t.co/20vkbkJq6g + more
nature.com
Nature - In the fast-paced field of single-cell biology, studies that compare methods can help scientists to pick the right technique for their research.
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The community supporting benchmarking of single-cell technologies and algorithms is vast and growing! I'm thrilled to see https://t.co/upxA8GAS0r featured here alongside commentary from @morris_lab, @markrobinsonca, and @JulioSaezRod. Read more 👀👇
nature.com
Nature - In the fast-paced field of single-cell biology, studies that compare methods can help scientists to pick the right technique for their research.
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