Interested in tumour immunity, dendritic cells and immunotherapy? Excited to share our study on CCR7+ dendritic cells (DCs) in cancer out today, a joint effort between @LabWithers and @ClatworthyLab. (🧵 1/8).

If interested, do also check out our previous related work using the Kaede model to study the temporal dynamics of *DCs* (, *NK cells* ( and *T cells* (; review article (.

Join millions who have switched to Grok.

We identify spatially, temporally and functionally distinct tumour-associated macrophage (TAM) populations that undergo rapid changes following tumour infiltration. Immune checkpoint therapy promotes pro-inflammatory IFNγ-driven responses in newly-entered monocyte-derived TAMs.

Our latest study using the photo-convertible Kaede model to track tumour-infiltrating leukocytes and their changes over time is now out in @CIR_AACR! @ClatworthyLab @LabWithers.

RT @KelvinTuong: We have a PhD position opening for Australian domestic students interested to work at the intersection of immunology, data….

RT @cathrine_sant: CHOIR is now online @NatureGenet! CHOIR is a new clustering method for single-cell data that evaluates whether clusters….

RT @MasudHusain: Thank goodness people are waking up to the fact that there is a crisis for clinical research in the UK @FT .High on the l….

RT @LabWaggoner: Review @jacionline @ClatworthyLab @ColinYCLee .Profiling immune cell tissue niches in the spatial -omics era. https://t.co/….

RT @kosa12matyas: Most rigorous ML paper

Check out our discussion (@ClatworthyLab) on the use of Spatial Transcriptomics for investigating immune niches in this month's issue of @jacionline.

RT @jacionline: Recent developments in high-throughput spatial -omics technologies have facilitated a more comprehensive understanding of t….

Huge! 🎉🎉.

RT @KelvinTuong: Veryy happy to share that I got lucky this round and was successful in my #NHMRC Investigator Grant! Thanks to my past and….

RT @MLynall: Fancy a 4-year post-doc in Cambridge, working in both the biggest biomedical centre in Europe @psychiatry_ucam @CambridgeBRC a….

RT @itchdoctor: Cancer neuroimmunology is real. Nociceptive neurons promote gastric tumour progression via a CGRP–RAMP1 axis | Nature https….

RT @Nature: A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the….

RT @tangming2005: The Hardest Part of Bioinformatics? Naming Files.1/ What’s the most challenging thing in bioinformatics? It’s not coding.….

RT @jitcancer: New #JITC article: Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer t….

RT @BrainTumourOrg: We have awarded £150,000 as part of our Expanding Theories grant to Dr @elizabeth_lee22 and her team at the @CRUK_CI. T….

RT @KelvinTuong:

RT @m_rashidian1: 1. Excited to share our paper published in @Nature today, introducing CD45-PET as a robust approach for noninvasively im….