Excited to share our latest paper! At @InstitutoCajal under @JLTrejo2 supervision, in collaboration with @isen_gard & @jfcryan. Moderate exercise boosts memory & neurogenesis in mice via gut microbiome 🏃‍♀️🧠🦠 Only moderate microbiota transfers benefits. https://t.co/OpPeY5VC77

❝ Conditions such as gut-related stress, pain and anxiety showed up more frequently in women, and I began to wonder if it was differences in the microbiome driving this.❞ APC's Prof @somahony1 (@FemmeBiome & @ucc) is interviewed in @IrishTimes 📰 https://t.co/7hIBjHOfbf

Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly | Cell Death & Differentiation

Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology

¡Enhorabuena a Marta Montero Atalaya por su Tesis Doctoral defendida en el CIAL! 👏 🧠 Tesis clave: Dieta, microbiota y patología Tau en Alzheimer en fase leve. Su estudio con polifenoles abre camino a la prevención vía nutricional. #Tesis #Alzheimer #Microbiota #Investigación

Gut brain communication. A review of the distinct spinal and vagal afferent types alongside viscerofugal pathways revealed by advances in neurogenetic techniques and high-resolution anterograde tracing

Exercise and the blood–brain barrier: Mechanistic insights and therapeutic implications https://t.co/oZmfNYTd8L

Metabolism is an energetic circuitry that transcends cellular and organellar boundaries https://t.co/2pbzQ0glbO

Our gut microbiome may offer clues for appetite regulation @Cristinacuestam, @harschellekens, @jfcryan & colleagues explore the neuroactive potential of specific bacterial metabolites, based on in vitro supernatants: https://t.co/53FKv38Bzz

Un nuevo estudio del @CSIC @InstitutoCajal coordinado por José Luis Trejo @JLTrejo2 y Elisa Cintado @CintadoElisa, demostró que ejercitarse a ritmo medio aumenta la diversidad bacteriana intestinal, un indicador de salud. Vía @mundodeportivo

New! Online now: Paternal exercise confers endurance capacity to offspring through sperm microRNAs https://t.co/qD1eentGzQ

📰 "Revelan el papel de la microbiota intestinal en la plasticidad cerebral al regular los efectos cognitivos del ejercicio físico, como la mejora de la memoria y la generación de nuevas neuronas". 🔬 @JLTrejo2 @CintadoElisa 🏛️ @InstitutoCajal @CSIC https://t.co/KcTz0unVro

A recent eBioMedicine (@TheLancet) study suggests excessive exercise can cancel the memory & hippocampal benefits of moderate activity. 🧠 Gut #microbiota plays a key role in mediating these effects and promoting better cognitive performance. 👇 https://t.co/fQFwBDZyG4

Ageing is associated with cognitive decline & an increased risk of neurodegenerative diseases. A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing:

The gut-brain axis is a bidirectional communication network between the gastrointestinal tract and the central nervous system. This dynamic system integrates neural, endocrine, immune, and metabolic signals, many of which are modulated by the gut microbiota. 🧠 1. Neural Pathway

The microbiota modulates the positive impact of moderate physical exercise on memory. @CintadoElisa @JLTrejo2 @CSICdivulga @InstitutoCajal @SENC_ @isen_gard @jfcryan @Pharmabiotic https://t.co/id6Tb5Elg1

🏃#Salud | El CNC-@CSIC demuestra que el ejercicio moderado mejora memoria y neurogénesis gracias a cambios en la microbiota intestinal. Una intensidad excesiva reduce estos beneficios, según eBioMedicine @TheLancet @CintadoElisa  https://t.co/fs3wLlnz7G

La microbiota modula el impacto positivo del ejercicio físico moderado sobre la memoria por @CintadoElisa @JLTrejo2 @InstitutoCajal @CSICdivulga

El ejercicio necesario para mejorar la memoria y la microbiota: "Más no siempre es mejor" de @CintadoElisa y @JLTrejo2 @InstitutoCajal @CSICdivulga https://t.co/G3dQhRaRvK

🏊‍♂️🚴⛳️🏸 Great new APC paper on moderate #exercise boosting memory & neurogenesis in mice via gut #microbiome from @jfcryan, @isen_gard, Klara Vlckovab & @bpvalderrama @ucc in collaboration with @InstitutoCajal / @JLTrejo2 📕 https://t.co/WuqX9F8Dis 📰 https://t.co/M8O5skQbC4

In mice, maternal antibodies ingested in breast milk in the first week after birth help to regulate immune responses in the newborn gut, according to a new study in Science. This process builds the important partnership between the microbiome and host at an early stage, paving