Christina Demetriadou
@ChristiDemet
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Postdoc at @WellenLab & @mzspectrum • PhD @KirmizisLab • alum @UCYOfficial & @UniofNottingham • #epigenetics and #metabolism enthusiast 🧬🔬
Philadelphia
Joined April 2021
Thrilled to see this paper out!! Huge congrats to the brilliant @ArielKlavaris 🎉so proud of you and all your hard work❤️ #NAA40.
📢 Our new paper is out! @KirmizisLab .H2A.X is N-terminally acetylated by NAA40–a novel histone mod responsive to UV irradiation. Thanks to all authors @BonaldiTiziana @CosKouf @ChristiDemet @N_Dietis anonymous reviewers & @EpigenChromatin Editorial team.
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Thank you so much @Aiims1742 for the amazing discussion and feedback!!!.
This preprint was my favorite scholar in training award poster at #AACR25. Brilliant work by @ChristiDemet from Kate Wellen lab @PennCancer .A nuclear branched-chain amino acid catabolism pathway controls histone propionylation in #PancreaticCancer .
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RT @MSciacovelliLab: Very cool work about the role of the branched-chain amino acids in regulating transcription in pancreatic cancer via h….
biorxiv.org
Branched-chain amino acid (BCAA) catabolism contributes prominently to the TCA cycle in the healthy pancreas but is suppressed in pancreatic ductal adenocarcinoma (PDA). The impact of this metabolic...
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RT @biorxiv_cancer: A nuclear branched-chain amino acid catabolism pathway controls histone propionylation in pancreatic cancer https://t.c….
biorxiv.org
Branched-chain amino acid (BCAA) catabolism contributes prominently to the TCA cycle in the healthy pancreas but is suppressed in pancreatic ductal adenocarcinoma (PDA). The impact of this metabolic...
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I had the BEST time presenting my work at #AACR25 this week! Incredibly thankful to the organizers @Cosimo_Commisso @BoyiGan @mvh_lab for giving me this amazing opportunity!
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📢Nuclear metabolism alert 🎉Thrilled to share our new preprint from the Wellen lab and @mzspectrum lab. We discovered a nuclear BCAA catabolic pathway that regulates histone propionylation! So grateful to all our amazing collaborators!.
biorxiv.org
Branched-chain amino acid (BCAA) catabolism contributes prominently to the TCA cycle in the healthy pancreas but is suppressed in pancreatic ductal adenocarcinoma (PDA). The impact of this metabolic...
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RT @PennMedCSO: New research out in @CD_AACR finds that immunotherapy may boost KRAS-targeted therapy in pancreatic cancer ft. Ben Stanger….
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RT @KirmizisLab: ****Available PhD position in our group****.Offering one of the below funded positions with start in September 2025. More….
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RT @KirmizisLab: Very insightful review from @NAT_machinery on protein N-terminal acetylation biology and its impact on physiology. https….
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RT @trefely: We have an exciting postdoc opportunity at the interface of metabolism and epigenetics! 🔥🧬. The project will investigate novel….
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RT @PennMedCSO: ft. Joyce Liu, @laura_vpinheiro, @PhuongTTNguyen1, Jack Drummond, @nivmurali, @PrateekVSharma, @JuliannaSupplee, Mia Shiue,….
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RT @PennMedCSO: NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis ft. Brijesh Verma, Shweta….
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RT @PennMedCSO: Congratulations to @ChristiDemet (@WellenLab), recipient of the 2024 @AACR Anna D. Barker Basic Cancer Research Fellowship!….
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Soooo excited and honored to receive the @AACR - Anna D. Barker fellowship that will support my research on uncovering a new link between #metabolism and #epigenetics in #PDAC. Many thanks to my amazing mentors @WellenLab @mzspectrum for making this possible. Stay tuned!!!.
We congratulate Christina Demetriadou, PhD, recipient of the 2024 AACR Anna D. Barker Basic Cancer Research Fellowship. We look forward to her findings on the nuclear role of branched chain amino acid catabolism in pancreatic cancer growth and treatment resistance. @ChristiDemet
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RT @PennCancer: "Good Day Philadelphia" anchor Mike Jerrick (@MikeFOX29), pictured with co-host @AlexHolleyFOX29, shared his #ProstateCance….
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RT @PaulTitchenell: Great week in MA @FASEBorg #MMCSRC. Terrific lineup of speakers and exciting posters showcasing the most recent #metabo….
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RT @acarrer: Check out our newest review: Diet predisposes to pancreatic cancer through cellular nutrient sensing pathways - Noè - FEBS Let….
febs.onlinelibrary.wiley.com
Components abundant in western diets (including poly-unsaturated fatty acids, cholesterol, and fructose) can predispose to pancreatic cancer because they trigger the activation of specific nutrient...
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