Caroline Dean
@CarolineDeanLab
Followers
3K
Following
94
Media
20
Statuses
109
Professor Dame Caroline Dean's lab @JohnInnesCentre
Norwich, England
Joined June 2012
RT @Miguel_Montez_: We are happy to share our work on local #nucleosome dynamics integrating #temperature inputs into an #epigenetic switch….
0
21
0
RT @YiliangDing: In our new review paper, @ywan_wan and I focused on the functional importance of RNA structure in gene regulation. Many th….
0
77
0
RT @rcollepardo: We are hiring postdocs at @Cambridge_Uni. Join our diverse and inclusive team and help us understand chromatin phase trans….
0
94
0
RT @JohnInnesCentre: NEWS - How transcription delivers epigenetic silencing. Two new studies reveal core principles of how chromatin and tr….
0
15
0
RT @emateobonmati: And as back-to-back with this other modelling paper with my dear friend Govind Menon! From Martin Howard group AND @ReeS….
0
7
0
RT @emateobonmati: I am thrilled beyond words to share with you all that our work, previously posted as @biorxivpreprint, is now out in @Mo….
0
32
0
RT @geng_jen: I'm glad to share that one of my projects in @CarolineDeanLab is now published on bioRxiv. Thanks to all authors! We have use….
0
22
0
RT @emateobonmati: Today we started a very special meeting at @JohnInnesCentre. The first reunion of all Dean alumni. First time I saw live….
0
4
0
RT @PlantPhys: TOPICAL REVIEW: Flowering time: from physiology, through genetics to mechanism (Robert Maple, Pan Zhu, Jo Hepworth, Jia-Wei….
0
16
0
COOLAIR and PRC2 function in parallel to silence FLC during vernalization - out now! 🌱❄️Great effort by all the authors (on twt @_MathiasLN @emateobonmati @wolffsworld @shaolyyy).
Our paper is officially out @PNASnews . We aimed to better understand the role of lncRNA and Polycomb during FLC silencing. Elucidating their interplay required a combination of genetics, molecular biology, and, importantly, computational modelling. 👇.
1
23
71
After 4 years in the lab @ReeSvenja successfully defended her PhD on the spatio-temporal regulation of FLC last Friday! Pictured here with supervisor Martin Howard and @ReaLAntKour. Congratulations Dr. Svenja Reeck!!
7
10
96
Massive effort by all the authors and collaborators.@ReaLAntKour @meschichi @ReeSvenja @scottbscience Govind Menon @zhao_yusheng @JohnFoz Terri Holmes Lihua Zhao Huamei Wang Matthew Hartley Stefanie Rosa and Martin Howard.
1
0
8
Here is a cheat sheet for everyone who is not as familiar with the terms of digital and analog gene regulation as we are after over 10 year of joined group meetings with the Howard group 🧬💻🌱😀 @JohnInnesCentre
1
15
39
Excited to share with you our recent work on how different gene expression modes are integrated at FLC.
1
20
54
Another step closer to understanding the complexity of FLC regulation by showing that antisense transcription and PRC2 repression function in parallel during vernalization ❄️. Happy to share our recent work led by @_MathiasLN 🧬🌱and Govind Menon 💻.
0
16
64
All of this would not have been possible without the endless efforts of all the authors @emateobonmati Govind Menon @XiaofengFang1 @Bobby_Mapes Marc Fiedler @lapassmore @ReeSvenja Zhe Wu and Robert Ietswaart in this fruitful collaboration with the Howard group @JohnInnesCentre.
0
4
18
In the second paper led by Govind Menon, we developed a mathematical model to capture the different feedback mechanisms between co-transcriptional 3′ processing and chromatin modifications determining the rate at which Polycomb repression is established.
1
13
36
Today we submitted two exciting stories to bioRxiv: . Driven by @emateobonmati we show that "The CPSF phosphatase module links transcription termination to chromatin silencing"
1
20
56
This work was led by Elsa Franco-Echevarria in collaboration with the Mariann Bienz lab at @MRC_LMB.
0
0
3