Yue Wan
@ywan_wan
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RNA biology, structure, genomics
Singapore
Joined May 2017
Happy to share that we identified a conserved 17kb long-range RNA-RNA interaction in SARS-CoV-2 that impacts virus fitness. Congratulations to all the authors! https://t.co/j4GBE6OU3W
nature.com
Nature Communications - Yang et al. apply high-throughput structure probing approaches to characterize the secondary structure throughout the SARS-CoV-2 WT and VOC genomes, uncovering an...
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In GIS, we aim to use the power of genomics to make the world a better place. We are happy to be able to celebrate 25 years years of excellence with outstanding scientists in Singapore and across the world.
🎉 Celebrating 25 Years of Genomic Discovery & Innovation! 🎉 Last Friday, we marked a major milestone at the #GIS25 Genome Innovation & Precision Medicine Conference, bringing together an outstanding lineup of international and local experts. From RNA/DNA technologies to
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🎉 Celebrating 25 Years of Genomic Discovery & Innovation! 🎉 Last Friday, we marked a major milestone at the #GIS25 Genome Innovation & Precision Medicine Conference, bringing together an outstanding lineup of international and local experts. From RNA/DNA technologies to
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GENOME: THE GIS SPEAKER SERIES🧬 Join us at our next seminar by Dr. Rena Ren, Helen Hay Whitney Postdoctoral Fellow from Harvard Medical School/Broad Institute, hosted by Dr @ywan_wan Date: Mon 22 Sep 2025 Time: 10AM (SGT, GMT +8) Venue: Online via Zoom Link:
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Singapore RNA Seminar Series 🧬 Join us at our next seminar by Dr. Yoosik Kim, Associate Professor at Korea Advanced Institute of Science and Technology (KAIST) on "Exploiting the immunoregulatory potential of double-stranded RNAs" on 9 Sep 2025, 10:00AM (SGT, GMT+8). Host:
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Our RiNALMo RNA language model has been published in Nat Comm https://t.co/2EXzExKdzK Great work by @RJPenic and @TinVlasic, with support and patience in teaching us RNA biology from Roland G Huber and @ywan_wan RiNALMo is already an SOTA as a benchmark for RNA LLMs.
nature.com
Nature Communications - RiNALMo, a large-scale RNA language model trained on non-coding RNA sequences, captures structural information and achieves state-of-the-art performance on multiple tasks,...
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I am grateful to have been able to build my career at the Genome Institute of Singapore, A*STAR, where I have found mentors, collaborators, and lab members who inspire me every day. I look forward to continuing our studies on how RNAs can fold in health and disease.
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Singapore RNA Seminar Series 🧬 Join us at our next seminar by Dr. @EricMiska on 7 July 2025, 2:00PM (SGT, GMT+8). Host: Dr Wan Yue @ywan_wan Link: https://t.co/Nsmlq7uL7Q Webinar ID: 984 0996 0781 Passcode: 277278 Subscribe to our future RNA events: https://t.co/5oaxp205Ap
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As a genomics person, I couldn't think of a better place in Asia to work than the Genome Institute of Singapore. We are recruiting for RNA, AI and Precision health. If interested Principal Investigator, GIS job with Agency for Science, Technology and Research (A*STAR) | 673811
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Instead of pairing more, we observed that RNAs are more single-stranded in stress granules to enable recovery. RNA Structure Directs RNA Partitioning and is Actively Disrupted inside Stress Granules to Enable Cellular Recovery | bioRxiv
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Singapore RNA Seminar Series 🧬 Join us at our next seminar by Dr. @Sergiu_P_Pasca on 10 June 2025, 2:00PM (SGT, GMT+8). Host: Dr @ywan_wan Link: https://t.co/Eyk6xaoyc8 Webinar ID: 969 8098 1762 Passcode: 643820 Subscribe to our future RNA events: https://t.co/5oaxp20DpX
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Singapore RNA Seminar Series Join us at our next seminar by Dr. Shuo Han on Thursday 24 April 2025, 9.30am (SGT, GMT+8) Link: https://t.co/MVMe4yUrvz Webinar ID: 956 0990 0647 Passcode: 365938 Subscribe to our future RNA events: https://t.co/5oaxp20DpX
#RNA #Genomics
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🎉 Exciting News! 🎉 We are thrilled to announce that Dr. Suphavilai Chayaporn has been awarded the GIS Innovation Fellow FY24! 🏆 Dr. Suphavilai is spearheading an innovative project at GIS, aiming to develop clinical-grade metagenomic diagnostic systems for effective
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GENOME: THE GIS SPEAKER SERIES Join us at our next GIS Speaker Series seminar by Dr. Heng Li, Harvard Medical School & Dana-Farber Cancer Institute on Wednesday 12 March, 9.30am (SGT, GMT +8). Host: @msikic Webinar ID 985 9424 0029 Participant ID 371683 Passcode
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Singapore RNA Seminar Series Join us at our next seminar by Dr. Huipeng Jiao from Life Sciences Institute, Zhejiang University, on Tuesday 4 March at 11am (SGT). Webinar details: Webinar ID: 929 5538 3269 Passcode: 408776 Subscribe to our future RNA events at
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Happy to share that our characterisation of group I introns as circular RNAs is finally out! Congratulations to KC and all the coauthors.
academic.oup.com
Abstract. Circular RNAs are an increasingly important class of RNA molecules that can be engineered as RNA vaccines and therapeutics. Here, we screened eig
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Impacting the world through genomics is our dream. Excited that GIS’ spin-off Nalagenetics can make a difference to leprosy patients in Indonesia.
@nalagenetics, a spin-off from A*STAR Genome Institute of Singapore (A*STAR GIS), is set to revolutionize leprosy treatment in Indonesia with a nationwide genetic screening program starting in Q4 2025. This follows a successful five-year pilot with their PGx1301 diagnostic kit in
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