Christian E. Stieger
@CEStieger
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Chemist with a passion for phosphorus and proteomics | Phd @LeibnizFMP with @PhosphorusFive | now Postdoc @UCBerkeley with @dannomura
Berlin, Germany
Joined September 2018
🚀 Excited to share our latest @biorxivpreprint by @CEStieger We unveil TRACERs - Transcriptional Regulation via Active Control of Epigenetic Reprogramming - a new small-molecule-based induced-proximity modality that silences transcription factors by recruiting endogenous
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Excited to showcase published version of our covalent destabilizing MYC degrader in @angew_chem that stereoselectively targets an IDR C203 in MYC! Congrats to Hannah Rosen and Kelvin Li & thanks to #TomMaimone, @NovartisScience & @TheMarkFdn!
onlinelibrary.wiley.com
This study reports stereoselective sulfinyl aziridine covalent ligands that directly degrade the oncogenic transcription factor MYC by engaging intrinsically disordered cysteine C203. Lead compound...
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🔥It's finally out in @NatureChemistry @NaturePortfolio! @PhosphorusFive @LeibnizFMP developed #DarTlabeling🎯, a #proximitylabeling method using a biocompatible, easily synthesized, and chemically benign deazaflavin #photocatalyst
https://t.co/Vw2t5Cl73U
@SN and #SNAuthor.
nature.com
Nature Chemistry - Current photoproximity labelling methods often require metal-based catalysts to map protein interactomes but, owing to their toxicity, they have limited intracellular...
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Congress specifically banned NIH from doing anything to change how indirect costs are determined. So the recent fiat is a hasty, illegal mistake. https://t.co/ZaV74auJhw
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During our investigation of protein pyrophosphorylation, we identified a novel post-translational modification (PTM), which we have termed 'Protein Oligophosphorylation'. https://t.co/dFOJilk9kh
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Ein wichtiger Schritt um die Ausbildung von Wissenschaftlichen Mitarbeitern zu würdigen!
Als Antwort auf die allgemeinen Kostensteigerungen valorisiert der @FWF_at jedes Jahr die Personalkostensätze, die für Forschende bei der Beantragung von Projekten maßgeblich sind. Die für 2024 gültigen #Personalkostensätze sind jetzt online abrufbar.⤵️ https://t.co/Y2btmHxccv
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Als Antwort auf die allgemeinen Kostensteigerungen valorisiert der @FWF_at jedes Jahr die Personalkostensätze, die für Forschende bei der Beantragung von Projekten maßgeblich sind. Die für 2024 gültigen #Personalkostensätze sind jetzt online abrufbar.⤵️ https://t.co/Y2btmHxccv
fwf.ac.at
Die für 2024 gültigen Personalkostensätze sind ab sofort online abrufbar.
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Tune in if you want to hear about the latest developments in P(V)-electrophile chemistry from @Tubulis_GmbH and the Hackenberger lab (@PhosphorusFive ). 👨🔬👩🔬🧪 I'm super excited to share my recent efforts to develop phospho-arginine phosphatase selective probes!
The 4th event of our Industrial P Chemistry Webinar will feature talks by Dr. C. Stieger (FMP-Berlin) and Dr. M.-A. Kasper (Tubulis, Planegg-Martinsried). This Thursday 1/11/24 at 5 pm (CET). Further information and registration at https://t.co/Ojhd329dBr. See you there!
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Dear international students and talents from around the world, note that German universities welcome foreign students, are tuition free and many subjects are taught in English. Germany has become an open and liberal society in contrast to what the UK government is implementing.
From today, the majority of foreign university students cannot bring family members to the UK. In 2024, we’re already delivering for the British people.
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Open access from this week's issue: "Cell-Surface-Retained Peptide Additives for the Cytosolic Delivery of Functional Proteins". Read the full article ➡️ https://t.co/mm10DuO4Gc
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#Hamas is in violation of all known Palestinian, Arab, and International (UN) laws. - In 2007, Hamas massacred 450 Fatah Palestinians, ejected Palestinian Authority (PA) and took over Gaza Strip in a coup. PA has boycotted Hamas since. - The Arab League endorsed in 1982, 2002,
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Personal Thoughts: (not for everyone, feel free to skip) For the longest time, I struggled with my identity. A Palestinian kid born inside Israel. Like…wtf. Many of my friends refuse to this day to say the word “Israel” and call themselves “Palestinian” only. But since I
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Well well well. "Nobel prize winner for mRNA vaccines discusses being demoted by UPenn"
thehill.com
Katalin Karikó, who is sharing the Nobel Prize in medicine for her work with mRNA vaccines, says she was previously demoted by the University of Pennsylvania for her research in that area. “I…
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Big congrats to our former member Dr. Caroline Knittel who was honored with the Max Bergmann Young Investigator Award for her dissertation! 🎉🥳 so happy to see your hard work being acknowledged!
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Great talk by Christian Stieger @CEStieger of the @PhosphorusFive lab at #ABPP2023. He talked about his work on phosphorous-based electrophiles for protein conjugation, cysteine profiling and proximity-induced labeling. https://t.co/EPSlMX4umP
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So thrilled to receive the Xiaoyu Hu Award of the Chinese Peptide Society. This medal traveled from 🇨🇳➡️ 🇺🇸 ➡️🇩🇪 right into the hands of those who deserve it the most: the hackenbee group! 🙏 to my 🇨🇳 peptide friends @LeibnizFMP @HumboldtChem and @David_Lab_MSK for delivery ❤️
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Friday was a great day to celebrate an Dr. Jacob's epic PhD defense! The best part, sitting on the Dr.Wagen pulled by @PhosphorusFive @LeibnizFMP @HumboldtUni
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Excited to share our recent work from the @clausen_lab published in @CellPressNews as part 2 of the BacPROTAC story. Here we use targeted protein degradation as an antibiotics strategy to induce self-elimination of essential mycobacterial Clp proteins. https://t.co/8AqzNw7tSY
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Super thrilled that BMS (@bmsnews) joined forces with @Tubulis_GmbH: they licensed our P5 labeling platform to develop ADCs for cancer treatment. So happy + thankful 🙏🎉 to all lab members past and present and the Tubulis team for making this possible.
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Resist the urge to print! We are excited to share that our lab is now certified by @My_Green_Lab as part of their #MyGreenLabCertification! Thank you for the tips and recommendations towards #LabSustainability and thanks to Sarah, our amazing green lab representative! @LeibnizFMP
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