Cecilia Domínguez Conde
@CDominguezConde
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Human immunology & genetics at high-throughput | Group Leader @humantechnopole
Milan
Joined August 2013
📢📢 Happy to share this first piece from my lab where we reflect on the opportunities and tradeoffs posed by technological advancements in single-cell transcriptomics ✨✨ Kudos to Matilde Conte @Mattty5_ and Azahara Fuentes @azahara_fuentes !! ➡️
Opportunities and tradeoffs in single-cell transcriptomic technologies
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Nature research paper: Monoallelic expression can govern penetrance of inborn errors of immunity
nature.com
Nature - Somatically determined preferential allelic expression of select genes that when mutated cause inborn errors of immunity corresponds with disease phenotypes, suggesting that the penetrance...
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Es #22qAwarenessDay en #22qawarenessmonth Conoces el #Sindrome22q11? 1/2000-4000 bebés nacen con Síndrome #22q11 Dar a conocerlo cosa de todos‼️ #HazVisible22q
#yoconozcoel22q Info @22q_es👇 https://t.co/AKOUtWoLD3 Gr. @22qAndalucia @MedServiceCare👇🏻 https://t.co/w3gm6OsSBz
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FcγRIII+ CD8+ T cells elicited in utero by HCMV infection can execute Fc-mediated effector functions bridging cellular and humoral immunity, a promising target for Ab-based therapeutics in early life @jclinicalinvest @eleanor_semmes @SalliePermar
https://t.co/uvNZORMHfY
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In absolutely perfect timing for #ASHG24 I am so pleased to announce the labs second manuscript that was entirely conducted @humantechnopole. Here we showcase the power of diffusion autoencoders for phenotyping time resolved cardiac MRIs in 70k subjects. https://t.co/ep4J6CkNkq
medrxiv.org
Biobank-scale imaging provides a unique opportunity to characterise structural and functional cardiac phenotypes and how they relate to disease outcomes. However, deriving specific phenotypes from...
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🐣 So happy! With @francesconica13 and many others we’ve put together a network of >20 labs in Milan working on various flavors of RNA biology. Looking forward to a year of stellar talks by students and postdocs, new ideas, collaborations and much more @RNASociety @lexogen
🚀The Milan #RNASalon is on! 21 labs working on RNA biology from 10 institutions in Milan meeting monthly for scientific talks, new collaborations, networking and much more. Kick-off 29 Nov at HT. Many thanks to @RNASociety and @lexogen for their support! https://t.co/mDv401F5iV
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Postdoc position in my group closing in 6 days. Please apply! If you want to apply your ML/computer vision/computational skills to impactful biological/medical problems, helping us understand a range of diseases, please join us @humantechnopole
https://t.co/lGlIY3qDff
nature.com
APPLICATION CLOSING DATE: October 15th, 2024 Human Technopole (HT) is an interdisciplinary life science research institute, created and supported b...
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👉 Out now @NatureRevGenet: we CAN and we SHOULD do more to enable #genomic data sharing! 🧬🌏 👉Best practice examples and 12 actions we can all take together 👉 https://t.co/u81JZhxvfX
@GA4GH @AusGenomics @GenomicsEngland @NHSgms @AllofUsResearch @uk_biobank @ukfuturehealth
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7 years ago, I met a junior fellow named @JD_Buenrostro who blew me away with a vision of futuristic genomic technologies Today, we (@ajaylabade31, @carolinecomenho) are excited to share our first steps into that future: Expansion in situ genome sequencing 1/
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Hey #teamtomo!Our 1st❄️🔬work @humantechnopole is finally out!🥳 https://t.co/Q75zt93UV4 Serialized On-grid Lift-In Sectioning for Tomography(SOLIST) enables a biopsy at the nanoscale and high-res❄️STA from🧍♀️organoids and🐭liver, brain and heart tissue!Thread by @PeroneGaia below!
nature.com
Nature Methods - Serialized on-grid lift-in sectioning for tomography (SOLIST) improves the throughput of the serial lift-out technique for creating lamellas, addressing a major bottleneck in the...
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Our paper on the amylase locus is out in Nature ( https://t.co/oN247AmOKO)! Working with this team was incredibly fun! We developed a computational framework (cosigt) to infer the haplotype composition of short read samples leveraging the pangenome graph. 1/n
nature.com
Nature - The impact of structural variation on the evolution of the amylase genes is explored using human pangenome resources and ancient DNA data.
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We are hiring! Computational biologists interested in a postdoc in gene regulation join us @mele_lab! Check out our website https://t.co/x3ucohWhxX & e-mail me with a CV and a motivation letter before September 30th !
bsc.es
Transcriptomics and Functional Genomics Lab (TFGL)
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Take your career to the next level: #FacultyCall @ISTAustria is open! We're seeking exceptional group leaders in #chemistry, #ComputerScience, #DataScience, #EarthScience, #LifeSciences, #mathematics, and #SoftMatterPhysics to join our institute. Apply 🔗 https://t.co/6HZ4KAtAkN
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🌟Excited to be at #ECI2024 with my team & @BlagojeSoskic's lab! Do not miss tmr posters from my lab on neonatal immunity by @AlteaGjurgjaj and on long-read transcriptomics by @azahara_fuentes as well as talks from Soskic team on B cell genomics by @PietroDemela & PMarchesan!
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Check it out our latest review in @EurJImmunol on Guillain–Barré syndrome #GBS, exploring recent advances in its #immunopathology and novel clinical implications, building on our recent discovery of #Tcell immunity involvement.
onlinelibrary.wiley.com
Guillain–Barré syndrome (GBS) is a rare and heterogeneous disorder of the peripheral nervous system. Traditionally considered antibody-mediated, recent research highlights the involvement of autore...
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📢Still some time to register to BrainOmics 2.0! Theoretical+hands-on course for #singlecell #spatialomics in brain research @humantechnopole Incredible line up of speakers/instructors such as @N_Rajewsky @slinnarsson @GenesOfEve @MalyValerie @ahmedElkoussy and many more 👇
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Following the #HCA2024GM, we are delighted to announce two additional special sessions immediately following the 2024 HCA General Meeting. A Human Cell Atlas ‘Cells in Context’ Symposium & HCA Middle East Meeting will take place on 1 October at @humantechnopole @OrganoidAtlas
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We’re delighted to have Nicole Soranzo @nicolesoranzo & Yasmine Belkaid @BelkaidLab as our keynote speakers for the HCA General Meeting. You can see the full agenda at https://t.co/J96CTNejsH
#HCA2024GM
events.humancellatlas.org
The 2025 HCA General Meeting will convene our community to share updates on assembling HCA Atlases of specific tissues, and to plan for the release of the first draft Human Cell Atlas. We will...
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Variant-to-function dissection of rare non-coding GWAS loci with high impact on blood traits https://t.co/cFjVlFX9TX
#biorxiv_genetic
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🚨𝐇𝐞 𝐋𝐚𝐛 job opportunity @UCSF 🚨: I'm hiring TWO postdocs - an experimentalist and a computational biologist. Join us to use cutting-edge single-cell and spatial technologies to unravel the mysteries of human tissues. https://t.co/QJqxMmrxGi
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