This is a neat idea for many organ-on-chip platforms 👍

Narayanan, V., Schappell, L. E., Mayer, ..., Gleghorn, J. P., & Conway, D. E. (2020). Osmotic Gradients in Epithelial Acini Increase Mechanical Tension across E-cadherin, Drive Morphogenesis, and Maintain Homeostasis. Current Biology, #EpithelialMechanics https://t.co/rP5y4Mugj3

ICYMI: I have always been bothered by the fact that the vast majority of patients diagnosed with #PancreaticCancer have no single attributable risk factor. How can we identify more of such at-risk individuals BEFORE they get diagnosed, often with advanced stage disease? Grateful

Online @Cancer_Cell The crosstalk between macrophages and cancer cells potentiates #PancreaticCancer cachexia By Min Li & colleagues @StephensonCC https://t.co/dyuY8WQNrg

#PancreaticCancer-associated fibroblasts modulate macrophage differentiation via sialic acid-Siglec interactions https://t.co/Glw6R58PKc

Inflammation is a common feature of many human diseases. A special issue of Science highlights recent advances in our understanding of #inflammation, especially its role in homeostasis, cell death, viral infection, and more. Read more on #WorldHealthDay: https://t.co/mDpG4M5Cxw

In the latest issue! Cancer biomarkers: Emerging trends and clinical implications for personalized treatment

The first clinical trial using a mRNA-nanoparticle to deliver a protein replacement, which gets into liver cells and restores mitochondrial function. For a life-threatening, ultra-rare disease that has no treatment. New @Nature, with results in 16 patients https://t.co/K49K9wfOcK

New experiments uncover how cancer-associated fibroblasts shape the #tumor microenvironment by “donating” packages of proteins to surrounding cells—hinting that disrupting these communication lines might yield therapeutic benefits. @SciSignal https://t.co/dJMwJdhvuj

I love this illustration so much. 🤩 It’s a veritable roadmap for program setting in cancer research. Outstanding job by the all 🌟 crew of authors. https://t.co/1NCVMEVdcl

New preprint from @LoweLabMSKCC showing how the interplay between canonical genomic alterations like SMAD4 loss & tissue resident epigenomic drivers (KLF4, RUNX1) impacts tissue specific metastatic behavior (liver versus lung). https://t.co/QA4whkFmiD @dana_peer @ciacobu

From animal testing to in vitro systems: advancing standardization in #MPS Led by Darwin Reyes @NIST & Nureddin Ashammakhi @MSUMD, featuring multidisciplinary leaders from @US_FDA/@EUCouncil/academia/industry https://t.co/ZETLIt9HQI 📚 Reviews issue -

You need to be no expert to see the difference between the images below. Normal vs. angry microglia (🟣Iba1 marker) and how they interact with neurons (🟢Neun marker) when something wrong happens. This is one of the sides of neuroinflammation. #Alzheimer

Neurons (🟠) and microglia (🔵), brain's immune cells! Check the number of microglia available for each neuron. That's because this photo was taken in the cerebral cortex 🧠🔬. In humans, the glia-to-neuron ratio in the cerebral cortex is 3.72 (72% glia), while that in the

Nature research paper: Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance

New Research: Peritumoral brain zone in glioblastoma: biological, clinical and mechanical features: Glioblastoma is a highly aggressive and invasive tumor that affects the central nervous system (CNS). With a five-year survival rate of only… https://t.co/tMVWxFHpyp #immunology

Online Now: Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients https://t.co/RPy2cPfZZr

The OrganiX microfluidic system to recreate the complex tumour microenvironment https://t.co/8Ywb3PMiuz

📈 Trending Article in PNAS One of the most-viewed PNAS articles in the last week is “Bodily maps of emotions.” Explore the findings here: https://t.co/kdkKTprF1o For more trending articles, visit the PNAS homepage at https://t.co/V1ftRzw6u9.

Therapeutic potential of RNA-enriched Extracellular Vesicles 1: The next generation in RNA delivery via biogenic nanoparticles https://t.co/K4NsxPDPlj #genetherapy #celltherapy