Asif Ali
@Asifcellbio
Followers
124
Following
118
Media
2
Statuses
106
Postdoctoral Fellow, Biochemist, Molecular Biologist.
USA
Joined October 2018
RT @Eric_Betzig: MOSAIC lattice light sheet xy projection over 2+ hrs in human retinal pigment epithelial cells of endoplasmic reticulum re….
0
68
0
Hey #condensate enthusiasts, We just wrote a perspective piece describing biomolecular condensation as a preservation mechanism for orphan proteins during environmental changes. Preserve or destroy: Orphan protein proteostasis and the heat shock response
1
2
6
Generate videos in just a few seconds. Try Grok Imagine, free for a limited time.
396
661
3K
RT @NatureCellBio: ☕️In this issue: A Comment on #VolumeElectronMicroscopy, standards in sample preparation and image acquisition for enhan….
0
4
0
RT @ShorterLab: Design principles to tailor Hsp104 therapeutics
biorxiv.org
The hexameric AAA+ disaggregase, Hsp104, collaborates with Hsp70 and Hsp40 via its autoregulatory middle domain (MD) to solubilize aggregated protein conformers. However, how ATP- or ADP-specific MD...
0
7
0
RT @dallandrummond: Our recent work (led by @sammykeyport) on evolution of biomolecular condensation is now highlighted as a featured artic….
nature.com
Nature Communications - Cells must respond to environmental changes. In three fungal species adapted to different temperatures, cellular responses are conserved yet tuned to each organism’s...
0
15
0
RT @MolecularCell: Online Now: Nucleolar stress caused by arginine-rich peptides triggers a ribosomopathy and accelerates aging in mice htt….
0
65
0
RT @ShorterLab: Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient: Cell
cell.com
Proteins containing blocks of charged amino acids in intrinsically disordered regions contribute to the layered organization of nucleoli and establish distinct pH environments in nuclear condensates.
0
31
0
RT @mitchguttman: PRC2 is reported to bind RNA. Yet, genetic experiments have raised serious questions about their functional relevance. Ou….
0
111
0
RT @UChicago: Need a quiet space to read, relax or work? Visit the Arley D. Cathey Learning Center in this "study with me" style video. Hig….
0
3
0
RT @gpintilie: amazing integrative study of coronavirus NL63, with cryoET, sub-tomogram classification and averaging (@chiulab, @SLAClab),….
0
29
0
We are on Cover, #Chaperone #Condensates. Framing Heat Shock response as Condensostasis rather than Proteotoxic.
👋Our November issue's live! .Cover: #chaperone #condensates . 👉🏿Read: #MitochondrialMetabolism #neuron #mechanotransduction #PhaseSeparation #lipidhomeostasis #ribotoxic stress #genomestability #senescence #MitochondriaTransfer #DEI. & more!.
3
10
60
RT @NatureCellBio: 👋Our November issue's live! .Cover: #chaperone #condensates . 👉🏿Read: #MitochondrialMetabolism #neuron #mechano….
0
19
0
RT @DrJoshBlack: Check out the latest pre-print from the @GreenLabJHMI and @jingdongcheng labs! Here, my colleagues propose that LARP1 bind….
0
4
0
RT @NatureCellBio: ☕️NEW: @Mukherjee_Lab, Walter & co show that the secreted #Legionella protein SidI is a #tRNA mimic and #glycosyltransfe….
0
10
0
RT @DvdGently: Our structures of the #cardiac #sarcomere are now published in @Nature! With #teamtomo at @intein lab, we've used #CryoET to….
0
96
0
RT @NatureCellBio: ☕️NEW: Ali et al. show that, during #heatshock, aggregation-prone orphan #RibosomalProteins form #nucleolar-associated #….
nature.com
Nature Cell Biology - Ali et al. show that, during heat shock, aggregation-prone orphan ribosomal proteins form nucleolar-associated condensates that are kept in a liquid-like and reusable state...
0
11
0
Our @NatureCellBio story is picked up by UChicago News! .Taking look at inner working of cells to see how they respond to heat stress | University of Chicago News
news.uchicago.edu
State-of-the-art imaging techniques offer window into how cells conserve energy
0
3
21
RT @DrJoshBlack: I’m excited to share our News & Views article that @GreenLabJHMI and I wrote for @NatureCellBio on an exciting study from….
0
25
0
Our article is now live at Nature Cell Biology! representing a fantastic collaboration with @dallandrummond and squire lab. We demonstrated reversible storage of stress-induced orphan ribosomal proteins within chaperone-stirred liquid condensates. Dive in
8
27
111
RT @jomaa_lab: Want to know what happens when mitochondria get stressed? Check our latest pre-print with @SimoneMattei19 lab on how mitocho….
0
144
0