Anna Molofsky
@AnnaMolofskyLab
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brain immune communication throughout the lifespan and in neuropsychiatric diseases @annamolofskylab.bsky.social
San Francisco, CA
Joined July 2015
Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling
cell.com
In the postnatal mouse cortex, microglia use Wnts to direct astrocytes to reduce their contact with synapses prior to synapse engulfment by microglia. This mechanism allows microglia to instruct...
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amazing story from @Molofsky_lab on a cell type you've maybe never thought about but is critical to shape local immune responses after brain injury
Excited to share our research, spearheaded by MSTP trainee @nathanec1, with contributions from ~9 research labs, focused on the changing roles of brain fibroblasts (and immune cells) in brain injury. Thx in particular to @AnnaMolofskyLab, Tom Arnold lab. https://t.co/j2gWnMvmfX
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Our newest paper studying immunosuppressive astrocyte-GBM interactions using RABID-seq is out in @Nature today! Congrats to Brian Andersen and @CamiloFaustAkl! https://t.co/X9mq5dhw1v
nature.com
Nature - Using viral barcode tracing to detect interactions between glioblastoma cells and non-malignant astrocytes in patient samples, investigators discovered a pathway that reduces...
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Between alarms and sheltering, I learned last night that my postdoc mentor, Professor Atul Butte @atulbutte, has passed away, and he is only 55 years old. This is devastating news 💔. Atul was a giant in so many ways. He was a visionary leader in translational bioinformatics
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Among the shocking aspects of the @OfficialCCSF incident 1) leadership did not halt this antisemitic and personal attack. 2) an attendee is gleefully laughing throughout the entire tirade
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These things MUST happen: @OfficialCCSF must be held to account, and TERMINATE the employment of Maria Salazar-Colon. @SEIU221 must likewise terminate Colon’s employment. Colon should be fined and make RESTITUTION to the victim of her vile racism and antisemitism. Immediately.
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❤️👏🏻❤️👏🏻
This evening in Copenhagen, H.M. The King presented The Brain Prize to Professors Frank Winkler and @Michelle_Monje at the prestigious annual ceremony. Our heartfelt congratulations - an extraordinary recognition of pioneering contributions to #research into cancer neuroscience.
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The peer-reviewed version of expansion in situ genome sequencing is now out in Science! The news is bittersweet – when we first revealed this last September, I never guessed it would be my final paper in academia, but a lot has changed. A few parting thoughts:
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In a new Review, scientists discuss how interactions between the nervous and immune systems could impact neurological disorders and allergy-related behaviors like food avoidance. @nick_mroz @AnnaMolofskyLab @Molofsky_lab Learn more in Science #Immunology: https://t.co/ipRvbnbg3d
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A rare but honest statement from @alzassociation about the dangerous myths being perpetuated by @RFKJr_Official about Alzheimer’s disease and our incredible research and progress. https://t.co/hFELiubxYx
alz.org
The Alzheimer's Association calls on HHS Secretary Kennedy to stop dangerous fabrications about the state of Alzheimer’s and dementia research.
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There is a remarkable extent of bi-directional crosstalk between the nervous system and Type 2 immunity (vs infectious parasites, allergens, irritants, and toxins). A new and superb review @SciImmunology
https://t.co/HJBoWwujHp
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There are days in life that shake you. I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at @Columbia & academic career... 1/🧵
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If the US claims to be punishing Columbia for allowing what it describes as “illegal protests” and failing to protect students from “anti-Semitic harassment on campus”, why is the gov mainly terminating medical, public & environmental health funding that keeps us safe? 6/
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Terrorists must go!
This is for Kfir and Ariel. Share this 🟧 in support of the Bibas family. May their memory be a blessing.
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Type 1 lymphocytes and interferon-γ accumulate in the thalamus and restrict seizure susceptibility after traumatic brain injury https://t.co/xYwpb0Hvnt
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Thrilled to share our latest work on how #SHIP1, a gene linked to #neurodegeneration, affects #microglia in early #brain development. Congrats to @Ales_matera, @AnneCompagnion and the many #collaborators @ImmunityCP @FBM_UNIL
https://t.co/xu8GgsBszu
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Big thank you to my personal hero for nominating me:)
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