Brain-Immune Communication Lab
@AleksDeLab
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Deczkowska (@ADeczk) Lab for Brain-Immune Communication at Institut Pasteur. Untangling how body instructs the brain (choroid plexus FTW).
Joined May 2020
And it's out! The BIC lab presents our new perspective article on "Immune Control of Brain Physiology" - fresh off the press at @NatRevImmunol
https://t.co/WgTcbrUsOF wonderful synergy @_marikovacs @Ali_MoussaSamir and twitterless Amaia Dominguez-Belloso.
nature.com
Nature Reviews Immunology - The peripheral immune system communicates with the brain through diverse anatomical routes to shape brain physiology. Here we discuss why such diversity is needed and...
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Very happy to share this recent @AleksDeLab production!
Excited to share our new preprint: “Local B cell maturation and mast cell regulation of choroid plexus function in early life” https://t.co/qauBcU7715 initiated in the lab by @LaetitiaTravier and led by the one and only @Ali_MoussaSamir
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A massive global review just confirmed it. Clinical trials + real-world data from 132 million people across the globe. The HPV vaccine doesn’t just reduce cervical cancer. It almost eliminates it. Yes, you read that right. Girls vaccinated before 16 have an 80% lower risk of
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Australia just recorded zero cervical cancer cases in women under 25 - for the first time since records began in 1982. This is what happens when a country commits to HPV vaccination and screening. We protect our girls and save lives.
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Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity: @CellCellPress
https://t.co/k81zxKDAxv
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Granzyme K+ CD8 T cells slow tauopathy progression by targeting microglia https://t.co/EpA81oOkSj
nature.com
Nature Immunology - McGavern and colleagues identified a CD8+ T cell population that expresses GZMK in ʽtau-richʼ brains, where it may play a protective role against neurodegeneration.
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It’s no secret that we do our best work when it's less like work and more like a joy. That’s what we have in mind for Woodstock Night Science. The idea is to have the most fun conference possible so that good ideas flow and we all get inspired. That's needed now more than ever!
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Pyrolysis gas chromatography-mass spectrometry reveals the presence of micro- and nanoplastics in human kidney, liver, and brain tissue samples from 2016 and 2024, with higher proportions found in the brain https://t.co/Ur308ddWnN
nature.com
Nature Medicine - Pyrolysis gas chromatography–mass spectrometry reveals the presence of microplastics and nanoplastics in human kidney, liver and brain tissue samples from 2016 and 2024,...
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#WeekendRead! #LipidPower! Hugues &co show @NatureComms that lymphatic endothelial cells modify cholesterol into oxysterols, blocking PPARg in intratumor macrophages & monocytes, making them more inflammatory thus potentiating anti-tumor T cell responses!!
nature.com
Nature Communications - VEGF-C induced lymphangiogenesis combined with immunotherapy approaches can promote anti-tumor immune responses. Here the authors report that lymphaticderived oxysterols...
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And discuss how these routes are used for development and maintenance but become hijacked or modified in aging and pathology. Hope You enjoy it!
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Specifically we describe the routes that peripheral immune cells and signals use to shape the brain directly or indirectly.
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In this text we discuss how peripheral immune involvement in brain development, function and (anti-aging) maintenance is a feature, not a bug.
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📽️🇫🇷✅Please vote for 'Forgotten'✅🇫🇷 📽️ We are pleased to have supported this short powerful film by @AssoCLEnfants, directed by Alexandre Lenis for the @festivalnikon
https://t.co/PsNdIFl3Af
#CovidLongPediatrique #LongCovidKids #LongCovid
festivalnikon.fr
Bienvenue sur le site de la 16ème édition du Nikon Film Festival #nikonfilmfestival
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Our latest paper on neuronal resilience. The apoptotic pathway is activated as a transient pulse in neurons even with continuous apoptotic stimulus. Neurons prepare for survival even when they activate apoptotic signaling. Congrats Keeley and others!! https://t.co/wWw29m6rrU
nature.com
Cell Death & Differentiation - Apoptosis signaling is activated as a transient pulse in neurons
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❇️ Ce 22 octobre, l’Institut illumine ses bâtiments en vert pour soutenir le syndrome Phelan-McDermid (PMS), un trouble génétique associé à un retard du développement et à l’autisme. Les recherches sur SHANK3 ouvrent la voie à des essais cliniques prometteurs. 💚 #ShineGreen
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Corning now offers sterile tips that come in a paper container, thus generating less plastic waste!
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Neuropeptide signalling orchestrates T cell differentiation @Nature
https://t.co/pxXvYAJhiF
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These findings are from a study in @NatureNeuro which identified common genetic variants that affect rates of brain growth or atrophy in the first genome-wide association meta-analysis of changes in brain morphology across the lifespan. https://t.co/L0e03bYjqp 2/9
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An important study by F. Eun-Hyung Lee's team shows that long lived plasma cells (the source of long-term circulating antibodies) fail to establish after mRNA vaccination (even combined with SARS-CoV-2 infection). 🧵 (1/) https://t.co/Z15xiyxCLS
nature.com
Nature Medicine - The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in...
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