Adam Institoris
@AdamInstitoris
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Post doc at the University of Calgary interested in neurovascular coupling. Musician. Family man.
Joined April 2020
Bravo Milène! Beautiful imaging and rock solid human and animal data.
Our work showing a new role for the Alzheimer’s risk factor CD2AP in endothelial cells is finally published !.
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RT @CraigEdBrown: Pleased to share our new paper implicating #interleukin 10 in perturbed #brain #microcirculation and #cognitiveimpairment….
nature.com
Nature Metabolism - Interleukin-10 promotes the formation of microcirculatory defects in the brain associated with cognitive impairment in a mouse model of type 1 diabetes.
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RT @MTournissac: 🚨 Our work on neurovascular coupling and CO2 is online in @NatureComms 🥳.
nature.com
Nature Communications - A remerging hypothesis suggests that CO2 generated by neuronal metabolism contributes to neurovascular coupling (NVC). Here, the authors show that NVC is unaffected by the...
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Great work from the @JillStobart lab! They discovered a novel function of astrocyte NMDA-receptors. Congrats!.
Big news!! Our paper about astrocyte NMDA receptors is out in Nature Communications! This team effort was spearheaded by @NoushinAhmadpo1 @MeherKantroo.Thanks to the Reviewers for suggesting "mechanism" experiments that took this story to the next level!.
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RT @Mishra_CBF_Lab: Curious about how astrocytes regulate cerenbral blood flow? And all the perplexing findings, unanswered questions, and….
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Such an important line of research!.
It's out! The 1st paper of the lab on gut barrier led by the talented @elldonee in @BiologicalPsyc1 GOS 🥳🥂. Sex-specific impact of stress on the gut tight junctions, microbiota and we identified LBP as a gut/🩸 biomarker of stress 🐭 and depression 🙋🏻♀️.
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RT @CommsBio: Pharmacology and imaging of pericytes expressing GCaMP6f uncovers the basis of Ca2+ signaling in mid-capillary brain pericyte….
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RT @CNS_PDS: Can’t wait to see you THIS THURSDAY 12PM PT/ 3PM ET for another great set of talks featuring @CDMorrone and @milene_vandal zo….
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RT @CNS_PDS: But wait! There's more! @milene_vandal of @UCalgary will be presenting her work. Don't miss out 🇨🇦http….
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RT @cksalmo: #Astrocytes are hard to image accurately using light microscopy due to their convoluted maze of fine branches. .
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Our paper was featured on the Editor's highlight page in Nature Communications. Check it out if you haven't already!.
nature.com
On this page, we highlight some of the most exciting neuroscience papers that advance our understanding of the brain, covering neurodegeneration, neurological ...
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RT @JillStobart: Did you know that astrocytes express NMDA receptors? In our latest work, we show how these receptors regulate astrocyte ca….
biorxiv.org
Cortical astrocytes encode sensory information through their calcium dynamics, but it remains unclear if modulation of astrocyte calcium transients can change somatosensory circuits and behaviour in...
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RT @AndyShih_Lab: We are hiring a postdoctoral fellow to study mechanisms of brain microvascular dysfunction in aging and Alzheimer’s disea….
theshihlab.com
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A great team effort by Grant Gordon's lab, including @milene_vandal, @peringod and collaborators: @xinzhu_yu, @baljit_khakh, @neurophy and others.
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Our paper is out! .With genetic Ca2+ clamping and chemogenetic activation of astrocytes, we show that astrocytes enhance neurovascular coupling when neuronal activation is sustained but not when activation is brief.
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Very exciting findings by @Ciaran_MR with @AdedipeIfe and @Holt_LewisRhys on how astrocytes mediate cognitive and behavioural defects in adolescence induced by early-life stress. The astrocyte GR-knockout experiments are awesome!.
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RT @AstrocyteCafe: Astrocyte Cafe is happy to announce that Chris Dulla @DullaChris and Christabel Tan @xbel_tan will be presenting on comi….
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RT @cathnaledi: Come to the Cajal course on Neurovascular Function next year! Great speakers e.g. @AndyShih_Lab @NelsonLab1 @MartinMlauritz….
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RT @nlweilinger: Check out our new paper in @CellReports where we image pathological chloride microdomains and swelling in dendrites using….
cell.com
Neuropathological dendritic swelling and blebbing are shown by Weilinger et al. to be triggered by pathological, non-uniform [Cl–]i accumulation driven by NMDAR overstimulation and Ca2+ entry that...
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