Khyati Dalal
@08Kats05
Followers
90
Following
288
Media
3
Statuses
165
# Doctoral researcher @ Stowers Institute @KUMed @Zeitlinger lab #genomics #enhancer regulation #signalling factors #sequence rules
United States
Joined March 2011
Exciting news! Our work on Hippo pathway TF cis-regulation is now published in Cell Genomics!. Check it out here: Grateful to all co-authors who made this possible! @ZeitlingerLab .#HippoPathway #cisregulation #TFcooperativity #Deeplearning.
cell.com
Dalal et al. show how AI can be used to systematically uncover the sequence rules that guide how signaling pathways interact with DNA inside cells. This work provides a new lens for discovering the...
2
7
20
RT @NovakovskyG: Excited to share my first contribution here at Illumina! We developed PromoterAI, a deep neural network that accurately id….
0
33
0
RT @sandynandagopal: How does one (signaling) arm know what the other is doing in the cell? Through a network of bHLH transcription factors….
cell.com
Nandagopal et al. show how a network of bHLH transcription factors helps neural stem cells integrate BMP and LIF signaling to synergistically induce the astrocyte gene GFAP while suppressing factors...
0
14
0
RT @ScienceStowers: New #research from the @ZeitlingerLab uses #AI to decipher how cells respond to developmental cues, potentially paving….
0
3
0
RT @ewanbirney: So @JeremyFarrar asked for an "explainer thread" on Noble Prizes in Chemistry around AlphaFold and Protein design, so here….
0
147
0
RT @anshulkundaje: Check out @vr_scientist talk today at @cshlmeetings #BoG24 in the afternoon session on "Deciphering the cis-regulatory c….
0
16
0
RT @VirajDoddihal: I am thrilled to present the published version of my graduate work. We followed a bunch of crazy looking animals and the….
pnas.org
Successful regeneration of missing tissues requires seamless integration of positional information along the body axes. Planarians, which regenerat...
0
16
0
I'm very excited to share our recent work titled:"Interpretable deep learning reveals the sequence rules of Hippo signaling" is now on bioRxiv!.
In our latest work spearheaded by Khyati Dalal @08Kats05 , we use interpretable deep learning of genomic sequence information to tackle a long-standing question: How do signaling pathways regulate transcription in a cell-type-specific fashion? ( (1/8)
1
3
26
RT @FukayaLab: Delighted to share new review paper published in @TrendsCellBio ! We discuss emerging new models of enhancer functions, incl….
0
63
0
RT @naturemethods: It's that time of year!! 🎉We are so excited to announce our 2023 pick for Nature Methods' Method of the Year: methods fo….
0
223
0
RT @ZeitlingerLab: Are promoters just landing pads for the transcriptional machinery? No! They can be key regulatory centers during develop….
0
27
0
RT @aussiebiologist: We farewelled stellar post-doc @S0maDash to start her own lab in Biological Sciences @SUNY, @ualbany. Congratulations….
0
9
0
RT @xainabafzal: Many many congratses Dr Khyati Dalal!!! U did it 🙌🙌🙌 🎓🎓🎓🎉🎉🎉 happy fa all u have achieved by learning and applying new tech….
0
2
0
RT @anshulkundaje: This is by far the most convincing regulatory DNA synthetic design paper to date. Congrats to the authors 1/.
0
16
0
RT @ZeitlingerLab: Do only pioneer TFs open chromatin? No!. Does motif affinity affect how well pioneering TFs work? Yes!. Learn more by ch….
0
60
0
RT @Vijaygenome: Happy to share that our manuscript about role of Myc in placental development and ploidy regulation is published now. Than….
journals.biologists.com
Highlighted Article: Polyploidy is widespread in murine placental cell types. The transcription factor MYC supports polyploidy and prevents premature senescence in trophoblast giant cells.
0
10
0
RT @xainabafzal: Beautiful comparison by @RachelScanza of nascent transcripts in my paper to star and galaxy formation 🥰 🥰.Thank you thank….
0
3
0