Will Hooper Profile
Will Hooper

@willbfx

Followers
25
Following
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Statuses
20

bioinformatics scientist @nygenome — all opinions my own

NYC
Joined January 2021
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@nysfocus
New York Focus
3 months
NEW: Hotels and motels have quietly become New York’s most common solution for emergency shelter for homeless people outside NYC. Many stay in dilapidated rooms without the social services that shelters are required to provide. https://t.co/YdEHZn2157
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nysfocus.com
Statewide spending on hotels has more than tripled in recent years. The shift away from shelters has prevented families from accessing services like child…
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@FaltasLab
Dr. Bishoy M. Faltas
3 months
Grateful for the opportunity to present our CLONEVO investigator-initiated trial (IIT) in bladder cancer at @ASCO #ASCO2025. Here are some lessons I learned along the way: Investigator-initiated trials (IITs) are essential. IITs are clinical trials independently designed and led
@WCMGUcancer
WCM GU Cancer
4 months
Live at #ASCO25: Dr. Bishoy Faltas (@FaltasLab) presented results from the CLONEVO #ClinicalTrial for #BladderCancer that he led with other @WeillCornell #GU team members https://t.co/55Dk6gZWgc
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@landau_lab
Dan Landau
5 months
Excited to share our exploration @naturemethods into new horizons opening up in the era of low cost sequencing! 🔥 Deeper sequencing at WGS scale for PPM sensitivity of tumor informed MRD 🔥Duplex sequencing at WGS scale for plasma only exploration of ctDNA Check out thread 👇
@AlexandrePCheng
Alexandre Pellan Cheng
5 months
What happens when sequencing costs go ⏬ ? Imagination and new opportunities go ⏫ @landau_lab Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the @UltimaGenomics platform 🧵👇 Lets goooo!! https://t.co/ZMaJqUKNDK
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@FaltasLab
Dr. Bishoy M. Faltas
10 months
Good time to read our Tweetorial/ X-planation of our https://t.co/sU6uF9rfGa paper now featured on the cover of @Nature!
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@FaltasLab
Dr. Bishoy M. Faltas
11 months
🚀Big News! Excited to share our work “The Interplay of Mutagenesis and ecDNA Shapes Urothelial Cancer Evolution” published in @Nature! https://t.co/sU6uF9rNvI
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@FaltasLab
Dr. Bishoy M. Faltas
11 months
🚀Big News! Excited to share our work “The Interplay of Mutagenesis and ecDNA Shapes Urothelial Cancer Evolution” published in @Nature! https://t.co/sU6uF9rNvI
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@notSoJunkDNA
Nicolas Robine
11 months
Special nugget for my genomics friends in today's paper: Read everything but don't miss Extended Data Fig. 8, where @willbfx assembled a CCND1-ecDNA from @nanopore reads!
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@landau_lab
Dan Landau
1 year
"Did you know that you don't need targeted panels for ultra-sensitive MRD?" 🥳 Down right ebullient to share our latest 🥳@NatureMedicine ! MRD-EDGE leverages advanced #ML for #WGS #ctDNA detection across clinical context https://t.co/drJasWVwoE #DeepLearning 🪡
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nature.com
Nature Medicine - Detection of circulating tumor DNA using MRD-EDGE, a machine-learning-guided single-nucleotide variant and copy-number variant detection platform for signal enrichment, enables...
@allurequinn
pop culture gal
2 years
some #GoldenGlobes tea😭😭 “i asked for a picture with him and she (kylie jenner) said no” – selena gomez “with timothee?” *selena nods*
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@KentsisResearch
Kentsis Research Group
1 year
Human cancer is a disease of somatic mutations. As we age, tissues accumulate errors in DNA, but what causes mutations in young healthy cells? Read our new paper “Childhood cancer mutagenesis caused by transposase-derived PGBD5” https://t.co/B3RKAtYIWd 1/n
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science.org
Induction of somatic oncogenic mutations by the domesticated transposase-derived gene PGBD5 promotes medulloblastoma development.
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@notSoJunkDNA
Nicolas Robine
2 years
We (@nygenome cancer compbio group) are very fortunate to work closely with @WCMEnglanderIPM and have several papers in preparation. Here is one focused on brain metastases in prostate cancer with @FKhaniPath @willbfx @mishabeltran https://t.co/v7rT6XQV3v
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@DrChoueiri
Toni Choueiri, MD
2 years
I like very much this work from @FaltasLab in bladder cancer. It is innovative and an example of tumor evolution. It builds on what we know from #TracerX with @CharlesSwanton’ group. Bravo Bishoy! @OncoAlert @Cornell @DanaFarber_GU @OncoBellmunt @CharleneMantia @bergsa83
@FaltasLab
Dr. Bishoy M. Faltas
2 years
Pre-print alert 🚨Excited to share our new preprint “The interplay between mutagenesis and extrachromosomal DNA shapes urothelial cancer evolution” 🧬🔬#bladdercancer https://t.co/lDZf36CpB9 @OncoAlert
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@FaltasLab
Dr. Bishoy M. Faltas
2 years
Pre-print alert 🚨Excited to share our new preprint “The interplay between mutagenesis and extrachromosomal DNA shapes urothelial cancer evolution” 🧬🔬#bladdercancer https://t.co/lDZf36CpB9 @OncoAlert
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@notSoJunkDNA
Nicolas Robine
2 years
[job] Join my group! Bioinformatics Analyst, Computational Biology @nygenome.
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jobs.silkroad.com
Find a career with New York Genome Center
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@GenomeWeb
GenomeWeb
3 years
NY Genome Center Team Harnesses Ultima Genomics Platform for High-Sensitivity ctDNA Sequencing. Taking advantage of the new platform’s low sequencing cost, the researchers sequenced cell-free circulating DNA (ccfDNA) in plasma at high depth for...
genomeweb.com
Taking advantage of the new platform's low sequencing cost, the researchers sequenced cell-free circulating DNA (ccfDNA) in plasma at high depth for sensitive cancer monitoring.
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@landau_lab
Dan Landau
3 years
🔥Extra-hot pre-print before this hellsite goes up in smoke 🔥 New horizons open up when sequencing costs go ↘️ @UltimaGenomics Interested in deep cfDNA WGS for ultra-sensitive cancer detection? Duplex sequencing at genome scale? https://t.co/DJeCo86ok8 Check out 🪡👇
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biorxiv.org
Circulating cell-free DNA (ccfDNA) sequencing for low-burden cancer monitoring is limited by sparsity of circulating tumor DNA (ctDNA), the abundance of genomic material within a plasma sample, and...
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@KentsisResearch
Kentsis Research Group
3 years
Read our latest on the causes of oncogenic DNA rearrangements in medulloblastomas, a common childhood brain tumor: Childhood cancer mutagenesis caused by a domesticated DNA transposase
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biorxiv.org
Genomic rearrangements are a hallmark of most solid tumors, including medulloblastoma, one of the most common brain tumors in children. Childhood cancers involve dysregulated cell development, but...
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@JMDiagn
The Journal of Molecular Diagnostics
4 years
"Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence", new #OpenAccess article from at @WUSTLmed, @EmmesCRO, and @SylvesterCancer (@univmiami). Full FREE article:
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jmdjournal.org
The U2AF1 gene is a core part of mRNA splicing machinery and frequently contains somatic mutations that contribute to oncogenesis in myelodysplastic syndrome, acute myeloid leukemia, and other...
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@landau_lab
Dan Landau
4 years
🎶It's raining pre-prints, hallelujah! 🎶 Delighted to share our next generation of ctDNA detection through whole genome mutational aggregation 👉MRD-EDGE 👈 With advanced machine learning signal enrichment we went further and deeper than ever before! https://t.co/0TZFDia4Zc
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