Appeal to the mass spec hive mind: has anyone successfully edited 96-well plate dimensions (specifically plate height/z-axis) for injection from the nanoElute?

Interesting paper by the group of @tatescience in @CellChemBiol. They predicted the accessibility of many cysteines in the human proteome based on AlphaFold2 structures and correlated this with their detection and ligandability inchemoproteomics.

Proteome-wide structural analysis identifies warhead- and coverage-specific biases in cysteine-focused chemoproteomics

Fast chromatographic gradients and glycoproteomics? In our latest study we show that the scanning dimension in scanning SWATH can be used to assign precursor masses to oxonium ions for glycopeptide quantification @whit3matt @RalserLab

I teach college music theory, but I'm also a new dad. I decided to combine my professional and personal identities and make a thread of music for babies where the adult musicians went way, way harder than they had to. (1/12)

In this incredibly project, the amazing @chr_messner measured quantitative proteome profiles of 5k yeast ko strains by microflow-SWATH, revealing new insights into system-level regulation of the proteome. https://t.co/22tzFO0mdd

We're looking for a Technical Specialist in Mass Spectrometry to join the Chemistry Department at Imperial's White City campus. Read about how the role can help us get the most of our state-of-the -art instruments

Proteome-wide structure-based accessibility analysis of ligandable and detectable cysteines in chemoproteomic datasets https://t.co/U05MMckYLt

🎉 New paper alert - work that started out as @whit3matt & @chr_messner 's CDC 2020 project is out now. The DC team developed a cool new pipeline to extract oxonium ion signals from scanningSWATH MS data to enable glycoprotein quantification. Congratulations team OxoScan-MS !🎉

A really fun project from my time in @RalserLab: we combined scanning SWATH with targeted oxonium ion extraction to generate glycopeptide maps of plasma/serum. Started from purified glycoproteins and made it all the way to a clinical cohort!

Excited to announce DIA-NN 1.8! A major update of our universal software suite for DIA proteomics. Library-free analysis that can outperform high quality DDA libraries, full support for PTMs. Cool papers on the new capabilities to follow!

As mass-spec proteomics is transcending limitations of throughput, the stage is open for bold experimentation! I highlight exciting advances from @RalserLab in the context of general trends and the new applications that they enable. https://t.co/FzhaDgEmBT

Ralserlab and @Sciex proudly present Scanning SWATH. Want to measure a precise human proteome in 30 seconds, and at lower cost than a complete blood count ? And you want thousands of them? Have a look. https://t.co/fY4XArejy5

Very excited to be leading a project in this year’s @TheCrick Data Challenge! Looking forward to the next two days of hacking 🥳

Markus Ralser @RalserLab: “It’s just brilliant […] Getting the EMBO Gold Medal means that people start to trust our findings, but at the beginning not everyone would say, ‘well done,’ and pat me on the back—no way.” https://t.co/WTihHUX1z2 @ChariteBerlin @TheCrick

https://t.co/c747ZPm5MH It took us one year from 1st preprint, to make it submission-ready: Proudly presenting Scanning SWATH a proteomic method that quantifies >1,400 protein groups w. 30 second gradients, and >4,500 prot grps in 5 mins. Proteomics has never been that fast.

"If we truly want science, not silence, we need to ask ourselves the hard question: why do we struggle to hear the voices of the...scientists who don't look...like Einstein?" Actually, the answer isn't hard at all. It's racism.

We have established our new proteomics platform developed @TheCrick, @ChariteBerlin for profiling #COVID19 patients. We found 27 biomarkers that distinguish mild from severe COVID19 according to @WHO criteria. Tremendous thanks to all who contributed!

Fantastic work by the @RalserLab using scanning #swath acquisition. Been with @SCIEXnews for 10 years now and the concept of entire quantitative proteomes in 5 minutes absolutely blows my mind! #proteomics

https://t.co/bNCzREjFtw With our Partner @SCIEXOmics , we have organized a wonderful one-day omics meeting @TheCrick . Participation is free, postdocs and students get flash talks, so spread the news!