Understanding Mixed Effects Models: A Simple Example Imagine researchers are testing a new drug to lower blood pressure. They give the drug to patients in 10 different hospitals and measure how much each patient’s blood pressure drops after taking the drug. Now, two things can

Scihub stopped uploading new articles. SciDB is a continuing effort which has the entire scihub collection AND new papers. https://t.co/7149JIdzKU

🔍 New research finds a high incidence of falls in adult ICU survivors. There may be a critical window for intervention of 3 months after discharge. Read the complete clinical investigation in Critical Care Medicine: https://t.co/aDXWAFq1zV #OpenAccess #SCCM #CritCareMed @SCCM

@ross_prager @ThinkingCC @khaycock2 @IM_Crit_ @EMNerd_ @emcrit @nickmmark @First10EM @katiewiskar 🙌

Original Article: A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline https://t.co/3Fv4wlNESh #CCR25 | @CritCareReviews

Presented at #CCR25: In the PROMIZING trial, proportional-assist ventilation with load-adjustable gain factors did not differ significantly from pressure-support ventilation with respect to the time to liberation from mechanical ventilation. Full trial results:

Presented at #CCR25: In a cluster-randomized, crossover trial, hospital-wide use of lactated Ringer’s solution as compared with normal saline did not alter the incidence of death or hospital readmission within 90 days. Full trial results: https://t.co/3Fv4wlNESh

Conservative oxygen therapy with a target SpO2 of 90% did not reduce 90-day all-cause mortality compared to usual oxygen therapy in mechanically ventilated adult patients. #CCR25 @CritCareReviews https://t.co/jANQEufF3f

🚨 In the results of a phase 3 trial released today, Dr. @ecgoligher @TGHRI_UHN and team show how stimulating the diaphragm may help patients on ventilators wean off faster & increase breathing muscle strength. 🔗 Read more:

#TARGETproteintrial has been published open access in @JAMA_current Download and read! Many thank @JAMA_current https://t.co/7U5FlVUg6P

🧠 Bayesian analysis in #clinicaltrials: how does it differ from the traditional approach? Bayesian analysis is being used w/ increasing frequency in #ICU research & brings advantages/disadvantages compared to traditional Frequentist techniques #Review https://t.co/fLJBLjaOqo

BRICnet: shaping landscape of #ICU research in 🇧🇷 & beyond 🔹Founded in 2007, has become a leading clin research network in ICU; ➡️ 71 publications ➡️ 15 RCTs & 14 obs.studies ➡️ Strategic partnerships w/ international networks like ANZICS, CCCTG, ESICM https://t.co/mEJz93aILB

Ever heard of BRICNET? It’s the 🇧🇷 Network for Critical Care Research—born in 2007 from a driven group of colleagues. Since then, it’s grown into a global force in critical care science. Proud to be part of this journey! @bricnetbr @critcarescience https://t.co/SrElCNIm8a

🆕💫 Narrative review @yourICM How to approach a patient hospitalized for pneumonia who is not responding to treatment? #idxposts https://t.co/4Mv79ZxMCA

Quem poderia imaginar…

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

🔥 ¿QUÉ MODELO DE REGRESIÓN DEBERÍAS ELEGIR? (UNA GUÍA SENCILLA) 🔥 ¿Te suena a conjuro estadístico esto de LM, GLM, GAMM, GLMM...? 🧙‍♂️ Tranquilidad. Vamos paso a paso. Te prometo solo necesitas realizar unos simples pasos para elegir el modelo más adecuado para tu problema:👇🧵

Someone made a helpful guide to accessing scientific papers:

The main results of the Brazilian Reproducibility Initiative (the project that started this account) are out in preprint form at @bioRxivpreprint: https://t.co/tOy6BKV8JL! Here is what we found: (🧵)

Using the Supraclavicular Approach to Ultrasound-Guided Subclavian Vein Cannulation. #POCUS #FOAMed #FOAMcc What’s your preferred approach for subclavian cannulation? 🔗 https://t.co/TYfiQXyXeJ