Sepsis subtypes & response to IV vitamin C.🧫3 sepsis subtypes based on inflammatory response profile among critically ill adults.🍋NO subtype benefitted from vit C; heterogeneity of effect in magnitude of harm.🍊similar cytokine network in all subtypes.🔓

LV diastolic dysfunction in septic shock.🖥️ LVDD highly prevalent.🪦 not associated with mortality or 💦 initial fluid balance but with 🫁 significantly lower P/F ratio.🫀LVDD improved in survivors, suggesting #sepsis induced impairment of LV relaxation.🔓

CMV in #ICU: be aware! .🩺 pathophysiology.🧫 infection & disease definitions.🔥 reactivation in non-immunocompromised pts .🕯️ CMV in immunocompromised critically ill.⚠️ incidence & risk factors.🔬 presentations & diagnosis.🩺 treatment & prevention .🔓

Life-supporting interventions in older ICU patients.🔎 > 230K pts in 🇯🇵 .🛟 many life-supporting interventions, ⬇️ with age.🏥 ½ of pts in 80s & 60% >90y did not return home.🔓 With editorial: how to provide better-tailored care? .🔓

GCS: evolution & future celebrating 🎂 50 anniversary.🗺️ since introduction, GCS has been rapidly adopted into clinical practice due to its simplicity.🧠 bedrock of assessment of acute #TBI, its use expanded to any pts at risk of impaired consciousness .🔓

RT @FOAMecmo: 🖥️ Difficult weaning can result from several causes, including impaired function of lung, heart, respiratory pump. #POCUS val….

#POCUS to facilitate weaning from MV .🖥️ ABCDE to assess readiness for weaning & diagnose/monitor failure.🖥️ aeration score/pleural effusion.🖥️ below diaphragm.🖥️ cardiac function.🖥️ diaphragm.🖥️ extra‑diaphragmatic muscles.🖥️ future. #echofirst #FOAMus.🔗

Enhancing procedural competency through #simulation.🔎50 #ICU interns/residents, no prior experience.🎓training on essential procedures + gamified skill-specific competency labels to create motivating environment.⬆️ competency/efficiency & ⬇️ errors .🔗

Using routinely collected #ICU data?.#AI models may assist in diagnosis, treatment & complex care, but before using for #datascience several challenges: quality, lacking long term outcomes, inherent bias, need for temporal updates, should be considered. 🔗

RT @YoheiM_MD: UKにおけるICU心エコー実施体制の調査. 96%のICUに心エコー認定医はいるが，1日通して1時間以内に緊急心エコー実施可能な体制が整っている施設はわずか15%. 本邦でもNPやレジデントのFOCUSスキル獲得はICU内外での心エコーへのアクセス….

🎉 Best wishes for a happy (& full of published papers) 2025 to the Intensive Care Medicine #ICM community! .📫 Do not forget to submit manuscripts at 🖋️ Instructions for authors/Submission guidelines

Can we use #AI to better treat acute kidney injury?.🤖 role of #ArtificialIntelligence.🔮 prediction & prevention of #AKI.🔍 AKI sub-phenotyping.🩺 (cross-specialty) AKI management.🚧 limitations.🔍 future research.#FOAMcc on @icmjournal.bsky.social.🔓

RT @LukeFlower1: 📣 Thank you @yourICM for sharing our findings with the ICM community. 🫀NEAT-ECHO demonstrated a need to improve UK echo p….

🧵2/2.🖥️ 89% had approved trainer, teaching provided in 55% .🖥️ 62% had an echo lead, only 44% of them had dedicated time for role. 🖥️ only 15% units reported all-hours access to emergency #echo, 42% unreliable/no access .🖥️ regional echocardiographer-to-bed ratio: 0.48 to 0.14.

Echocardiography in ICU.🔍survey by @TRICNetwork @ICS_updates @FICMNews & @BSEcho, 178 🇬🇧 critical care units .🖥️significant heterogeneity in provision.🖥️96% had accredited clinician.🖥️16% of medical staff accredited in FOCUS & 4% in advanced #echo.🔓🧵1/2

@AsianSepsis @TripathySwagata @sebastianttl @ganbold12 @mlevymd @PRICE_critcare @NaomiHammond @azevedo_lcp @esicmmassimo @LingLing7 @arthurkwizera @CLThwaites.

Managing adults with #sepsis in resource-limited settings.🔍 international Delphi consensus .🩺 statements complement existing guidelines where evidence is lacking + add relevant aspects of management of critically ill, providing additional guidance.🔓

⚖️ Recognizing unique ethical challenges in #ICU-based research (pts at high risk for adverse events, often unable to consent, relying on surrogates) essential to enhance transparency/understanding among researchers, research ethics committees, public.🔓

🎄 Happy Holidays from Intensive Care Medicine @yourICM to everyone celebrating this month! Thanks to our readers, #SoMe followers, authors, editors & reviewers for your support, and for your bedside work in the #ICU!

RT @zaidheartsci: Absolutely! AI in ICU hemodynamic management is revolutionizing patient care. Enhancing monitoring, predicting deteriorat….