umesh chopra
@umeshchopra17
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PhD Microbiology and Cell Biology Scientist in making 🧫🔬Interested in studying Host Pathogen interaction 🧬🦠 @IIScbangalore
Bangalore
Joined March 2022
The endoplasmic reticulum (ER) of the host cell may play a role in helping Salmonella bacteria escape detection, IISc study shows. Read more: https://t.co/Taytu1gP9L
#IIScresearch
@DipaLab_IISc
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Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling non‑invasive in‑vivo imaging from molecules to organisms, is out. https://t.co/B2GHHP5b0K
@Eric_Betzig @legant_lab
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“Thrilled to see the image I captured making it to the cover of mBio (ASM)! Grateful to Prof. @DipaLab_IISc and everyone who has been part of this incredible journey of understanding Salmonella vacuolar dynamics. 🔬✨”
2009: Eswarappa et. al established the single bacterium in a vacuole concept. On cover art- Infection and Immunity(ASM). 2025: Chopra https://t.co/AJuUXYyDVT delineated the mechanism. On cover art mBio(ASM). Salmonella is never homeless as the home gets divided with Salmonella
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Researching at a remote place is thrilling. Happy to share our recent article on how bacteria brings together the finer soil particles and prevent leaching loss of nutrients. #SoilHealth #microbes4climate #agriculture Enjoy reading https://t.co/bIzJFz0v84
link.springer.com
Current Microbiology - Leaching loss of nutrients from the agricultural field is a major concern in areas receiving excessive rainfall. The water-soluble nutrients are therefore lost due to...
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Endoplasmic reticulum facilitates the coordinated division of #Salmonella-containing vacuoles. New #mBio study by @umeshchopra17 @DipaLab_IISc. https://t.co/L6cQZHbHdU
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Excited to share another story from my PhD work, now out in @mbiojournal ! 🎉 We finally show how the Salmonella-containing vacuole (SCV) divides inside host cells, with the endoplasmic reticulum marking the division site. Interesting cell biology of Salmonella infection
#NewPaper🎉🎉 We show how Endoplasmic Reticulum participates in the coordinated division of Salmonella Containing Vacuole. Previously our group enlightened the concept of "One bacteria per vacuole" ( https://t.co/6KnLIxuVmO…) Check out our latest story https://t.co/DVvVqroR9d
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Salmonella effector SseL induces PD-L1 up-regulation and T cell inactivation via ß-catenin signalling axis ✅ Just Accepted 🔗 https://t.co/d0nwkeXd8o
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"Ever wondered how Salmonella manipulates the immune system to establish infection? 🦠 Check out our latest paper on immune modulation strategy of PD-L1 upregulation and T cell suppression during Salmonella infection! 🚀🔬 Happy to share my first first-author publication! 🎉
"When Umesh unravelled Salmonella's Secret to Immune Suppression" Read the story about Salmonella's immune escape in our latest finding published today in the prestigious Journal of Infectious Disease. Congratulations @umeshchopra17🎉💐 https://t.co/5WpaatSKyy
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Elated to congratulate Dr. @umeshchopra17 from my group for successfully defending his Ph.D Thesis on 2nd January 2025 with outstanding work in the field of deciphering the SCV division mechanism and the immuno-modulatory strategy employed by Salmonella Typhimurium. #IISc
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Sooo fascinating
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Thank you @embl @EMBO for providing the wonderful opportunity to present my PhD work during # innate immunity in host pathogen interaction conference #EESImmunity #heidelberg Had a great time with wonderful discussions and talks #Salmonella_containing_vacuole
@DipaLab_IISc
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The @WHO 2024 Bacterial Priority Pathogens List of public health importance. #AMR #tuberculosis rifampicin resistant now included https://t.co/obVxucRY6r…
https://t.co/wHB8iNV3OK
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Happy to share a part of research work from my PhD thesis. Big thanks @DipaLab_IISc for constant support and guidance Our recent preprint on Endoplasmic Reticulum contact sites facilitate the coordinated division of Salmonella containing vacuole (SCV)
Endoplasmic Reticulum contact sites facilitate the coordinated division of Salmonella-containing vacuole (SCV) https://t.co/UAEaE7PAgK
#bioRxiv
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Thanks to all the co authors @umeshchopra17 , @sebastian Raja, @kdeydas , @LICB_SMS @DipaLab_IISc @mahalingam lab
Proud moment for @anushreebh289|@tvmiiser @LICB_SMS Congratulations team!! Molecular Biology of the Cell
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Lynn Zechiedrick @LynnZechiedrich from @Baylor shared her work on secondary code of DNA supercoiling at #BTMO2023 held at @iiscbangalore Really cool work showing that negative supercoiling opens up DNA and flips bases out in a sequence specific manner.
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Join us at #BTMO2023 Looking forward to sharing our insights into two collaborative works. Come, visit us at poster no 115 and 116. @RydhamGoyal @anushreebh289 @DipaLab_IISc
#communication_in_science
#collaboration_in_science
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Come and have a look at the intriguing work taking place in our lab. At Biological Transactions: from Molecules to Organisms (BTMO-2023). Poster#115
#BTMO2023 @iiscbangalore
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Farewell treat to lab 🤩🎊🎉
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